Natural selection of mitochondria during somatic lifetime promotes healthy aging (original) (raw)

The paper discusses how mitochondrial biogenesis and variability drive adaptive selection of beneficial phenotypes, challenging the notion that mitochondrial gene variability is solely detrimental. It proposes that intermittent stressors followed by recovery can enhance mitochondrial health, emphasizing the role of fission and fusion mechanisms in this process. The conclusions suggest that adaptive stress responses may promote healthy aging and longevity through selective pressures on mitochondrial function.