p53 and IGFBP-3: Apoptosis and Cancer Protection (original) (raw)

p53-Dependent and p53-Independent Induction of Insulin-Like Growth Factor Binding Protein-3 by Deoxyribonucleic Acid Damage and Hypoxia

Cameron Koch

The Journal of Clinical Endocrinology & Metabolism, 2005

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Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling

Jesper Worm

Cancer Biology & Therapy, 2006

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IGFBP-3 mediates p53-induced apoptosis during serum starvation

Adda Grimberg

International Journal of Oncology, 2002

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Insulin-Like Growth Factor Factor Binding Protein-2 is a Novel Mediator of p53 Inhibition of Insulin-Like Growth Factor Signaling

Adda Grimberg

2015

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Increased p53-dependent apoptosis by the insulin-like growth factor binding protein IGFBP-3 in human colonic adenoma-derived cells

Tracey Collard

Cancer research, 2000

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IGFBp-3 prolongs the p53 response and enhances apoptosis following UV irradiation

Jeff Holly

International Journal of Cancer, 2000

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The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal

alex hongo

Molecular and cellular …, 1997

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The p53/IGF-1 receptor axis in the regulation of programmed cell death

M. Neuberg

1997

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Increased p53-dependent Apoptosis by the Insulin-like Growth Factor Binding Protein IGFBP-3 in Human Colonic Adenoma-derived Cells1

Tracey Collard

2000

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IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer

Youngman Oh

Cells, 2020

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IGF2: The Achilles' heel of p53-deficiency?

Frederic Clermont

EMBO Molecular Medicine, 2012

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Evidence implicating a mid-region sequence of IGFBP-3 in its specific IGF-independent actions

Jeff Holly

Journal of Cellular Biochemistry, 2002

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Regulation of insulin-like growth factor II P3 promoter by p53: a potential mechanism for tumorigenesis

John Brady

Cancer research, 1996

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Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: functional impact

A. Bartolazzi

Cancer Research, 2000

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The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

Kurt Engeland

Growth Hormone & IGF Research, 2005

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Unraveling Insulin-Like Growth Factor Binding Protein3 Actions in Human Disease

David Feldman

Endocrine Reviews, 2009

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The expression and function of IGFBP-3 in normal and malignant breast tissue

WILLIAM Ogunkolade

Anticancer research, 2009

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p53 Regulates insulin-like growth factor-I receptor gene expression in uterine serous carcinoma and predicts responsiveness to an insulin-like growth factor-I receptor-directed targeted therapy

Rive Sarfstein

European Journal of Cancer, 2012

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Insulin-Like Growth Factor (IGF) Binding Protein3 Attenuates Prostate Tumor Growth by IGF-Dependent and IGF-Independent Mechanisms

Suresh Mishra

Endocrinology, 2006

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Insulin-like Growth Factor Binding Protein-3 Induces Apoptosis in MCF7 Breast-Cancer Cells

omar ali

Biochemical and Biophysical Research Communications, 1997

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Faculty of 1000 evaluation for Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria

Steven Rosenzweig

F1000 - Post-publication peer review of the biomedical literature, 2007

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A non-IGF binding mutant of IGFBP-3 modulates cell function in breast epithelial cells

Colin McCaig

Biochemical and biophysical research communications, 2002

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Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

Christopher Fox Graham

Embo Molecular Medicine, 2012

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Oncogenes and Tumor Suppressors IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling

Bo Lu

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The effects of insulin-like growth factor binding protein-3 (IGFBP-3) on T47D breast cancer cells enriched for IGFBP-3 binding sites

Suresh Mishra

Molecular and Cellular Biochemistry, 2004

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Overexpression of P53 protein and local hGH, IGF-I, IGFBP-3, IGFBP-2 and PRL secretion by human breast cancer explants

Tomasz Milewicz, Ewa Gregoraszczuk

Neuro endocrinology letters, 2011

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Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer

Youngman Oh

Journal of Biological Chemistry, 2010

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Rapid Apoptosis Induction by IGFBP-3 Involves an Insulin-like Growth Factor-independent Nucleomitochondrial Translocation of RXRα/Nur77

liqun Ma

Journal of Biological Chemistry, 2005

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Insulin-like growth factor I, IGF binding protein 3, and IGFBP protease activity: relation to anthropometric indices in solid tumours or leukaemia

M Pollak

Archives of Disease in Childhood, 1999

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Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

M. Constancia

EMBO Molecular Medicine, 2012

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Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer

Demetri Spyropoulos

European Journal of Cancer, 2005

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Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis

Adda Grimberg

Journal of Cellular Physiology, 2000

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