Comparison of arterial and venous pH, bicarbonate, PCO2 and PO2 in initial … (original) (raw)
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Eurasian Journal of Emergency Medicine, 2021
Aim: This study aimed to determine the agreement between arterial blood gas (ABG) and venous blood gas (VBG) analyses in a pathologically diverse patient population who presented to the emergency department. Materials and Methods: This cross-sectional study was conducted in the emergency department of a tertiary care hospital during the period from February 2019 to June 2020. A total of 113 patients presenting with various medical conditions confirmed on ABG by a physician were recruited. Both arterial and venous blood samples were collected for blood gas analysis. Using a Bland-Altman plot, data obtained were analyzed for agreement. IBM SPSS version 22 was used for the data analysis. Results: Among the 113 study participants, the arterial and venous pH values, base excess, and bicarbonate level show acceptably narrow 95% limits of agreement in the Bland-Altman plot (−0.06 to 0.08, −4.08 to 2.30, and −2.59 to 0.89, respectively). Agreement in partial pressure of oxygen and oxygen saturation measurements was poor (95% limits of agreement, −8.38 to 101.06 and 0.35 to 0.58, respectively). Agreement of partial pressure of carbon dioxide shows an acceptably narrow agreement (95% limits of agreement, −10.61 to −2.18). Conclusion: VBG analysis for pH, bicarbonate, and base excess may be a reliable substitute for ABG analysis in the initial evaluation of adult patients presenting to the emergency department.
Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate
Emergency Medicine Journal, 2006
Objective: This study aimed to determine the extent of agreement between central venous and arterial values for pH, bicarbonate, base excess, and lactate in a group of intensive care unit (ICU) patients. Methods: A prospective study of a convenience sample of patients deemed by their treating doctor to require blood gas analysis as part of their clinical care in ICU. It compared pH, bicarbonate, base excess and lactate on arterial and central venous samples taken within five minutes of each other. Data were analysed using bias (Bland-Altman) methods. Results: A total of 168 matched sample pairs from 110 patients were entered into the study. All variables showed close agreement. The mean difference between arterial and venous values of pH was 0.03 pH units, for bicarbonate 0.52 mmol/l, for lactate 0.08 mmol/l, and for base excess 0.19 mmol/l. All showed acceptably narrow 95% limits of agreement. Conclusion: Central venous pH, bicarbonate, base excess, and lactate values showed a high level of agreement with the respective arterial values, with narrow 95% limits of agreement. These results suggest that venous values may be an acceptable substitute for arterial measurement in this clinical setting.
Cureus, 2023
Arterial blood gases (ABGs) are routinely done in critical clinical settings to ascertain acid-base status. Due to difficulties and the potential side effects following arterial blood sampling, much research has been done to find the possibility of using venous samples as an alternative. However, this comparison needs to be evaluated in various contexts. Hence, this systematic review aims to explore the differences, appropriateness, and alternatives of arterial versus venous blood gas (VBG) analysis in different acid-base states. A comprehensive literature search was conducted through electronic databases using the terms "ABG," "VBG," "Arterial Blood Gas," "Venous Blood Gas," and "Gas analysis." Studies' qualities were assessed by using Newcastle-Ottawa Quality Assessment Scale. Of 531 articles, 22 were included in the study after title, abstract, and full-text screening. Based on the Newcastle-Ottawa Quality Assessment Scale, 23% of the studies had good quality (score ≥ 7), 77% fair quality (score 2-6), and none of the studies had poor quality (score ≤ 1). Moreover, 22.5% of the included articles found a strong correlation between ABG and VBG. 73% compared arterial and VBG parameters among patients with any clinical contexts, 22.5% in respiratory diseases, and 4.5% in metabolic conditions, and their results had a significant disparity. There was a considerable discrepancy among authors about the appropriateness and utilization of VBG as an alternative to ABG. Our findings suggest that those studies did not consider physiological differences between venous and arterial blood values and obviated the significance of sampling procedures.
Bicarbonate (HCO3-) measurement in serum or plasma from a sample of venous blood is routinely practiced in hospital patient management. HCO3status can also be assumed from Blood gas analysis requiring arterial blood as sample which is cumbersome for both patients and doctors. This study was undertaken to evaluate the extent of agreement among biocarbonate values obtained during venous, arterial blood gas analysis and conventionally measured serum bicarbonate levels in a group of intensive care unit (ICU) patients to determine whether conventionally measured serum HCO3-(from peripheral venous blood) and calculated HCO3values (from arterial blood gas [ABG] analyzers) can be used interchangeably. A total of 51 adult patients with diverse medical conditions, presenting at a tertiary health centre ICU were enrolled in this study when deemed by the treating physician to have an ABG analysis. Arterial and venous samples were taken as close in time as possible for blood gas analysis and routine blood tests. Bland-Altman analyses were used to compare the three methods. The HCO3levels from ABG, Venous Blood gas (VBG) and tconventionally measured serum HCO3showed acceptably narrow 95% limits of agreement using the Bland-Altman method. VBG reveals higher level of agreement with the ABG bicarbonate values compared to measured serum HCO3-. Thus, venous blood can be an alternate for arterial blood where ABG analyzer is available. conventionaly serum HCO3measurements can also be useful and used as substitute for an expensive ABG analyzer in resource constrained health care sectors when required.
Calculated arterial blood gas values from a venous sample and pulse oximetry: Clinical validation
PLOS ONE
Background Arterial blood gases (ABG) are essential for assessment of patients with severe illness, but sampling is difficult in some settings and more painful than for peripheral venous blood gas (VBG). Venous to Arterial Conversion (v-TAC; OBIMedical ApS, Denmark) is a method to calculate ABG values from a VBG and pulse oximetry (SpO 2). The aim was to validate v-TAC against ABG for measuring pH, carbon dioxide (pCO 2) and oxygenation (pO 2). Methods Of 103 sample sets, 87 paired ABGs and VBGs with SpO 2 from 46 inpatients eligible for ABG met strict sampling criteria. Agreement was evaluated using mean difference with 95% limits of agreement (LoA) and Bland-Altman plots. Results v-TAC had very high agreement with ABG for pH (mean diff (ABG-v-TAC)-0.001; 95% LoA-0.017 to 0.016), pCO 2 (-0.14 kPa; 95% LoA-0.46 to 0.19) and moderate to high for pO 2 (-0.28 kPa; 95% LoA-1.31 to 0.76). For detecting hypercapnia (PaCO 2 >6.0 kPa), v-TAC had sensitivity 100%, specificity 93.8% and accuracy 97%. The accuracy of v-TAC for detecting hypoxemia (PaO 2 <8.0 kPa) was comparable to that of pulse oximetry. Agreement with ABG was higher for v-TAC than for VBG for all analyses. Conclusion Calculated arterial blood gases (v-TAC) from a venous sample and pulse oximetry were comparable to ABG values and may be useful for evaluation of blood gases in clinical settings. This could reduce the logistic burden of arterial sampling, facilitate improved screening and follow-up and reduce patient pain.
Prospective study to determine possible correlation between arterial and venous blood gas values
Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2010
Arterial blood gas analysis is an iatric component factor in the clinical evaluation of patients, but arterial puncture has many complications. Our study aimed to determine a correlation between arterial and venous blood gas values. A prospective comparison of 200 samples from 100 patients undergoing lumbar disc surgery was conducted. Arterial and venous samples were obtained simultaneously from each patient. The samples were analyzed and compared using SPSS version 16 software, with Pearson's correlation and 95% confidence intervals (CIs) of the difference. Arterial and venous values for pH, bicarbonate (HCO(3)), base excess (BE), buffer base (BB) and partial pressure of carbon dioxide (PCO(2)) showed close and direct correlation. The comparison showed the following: pH, r = 0.938, p <0.001 (95% CI, 0.019 to 0.032); HCO(3), r = 0.884, p <0.001 (95% CI, -2.65 to -1.99); BE, r = 0.861, p <0.001 (95% CI, -1.89 to -1.17); BB, r = 0.849, p < 0.001 (95% CI, -2.35 to -1.60...
Simple Algorithm of Arterial Blood Gas Analysis to Ensure Consistent, Correct and Quick Responses!
Arterial blood gas (ABG) analysis is an essential part of diagnosing and managing a patient's oxygenation, ventilation status as well as acid-base balance. The usefulness of this diagnostic tool is dependent on being able to correctly interpret the results. The body operates efficiently within a fairly narrow range of blood pH (acid-base balance). Even relatively small changes can be detrimental to cellular function. Disorders of acid-base balance can create complications in many disease states, and occasionally the abnormality may be so severe so as to become a life-threatening risk factor. A thorough understanding of acid-base balance is mandatory for physicians, intensivists, and anesthesiologists are not exception! We must always interpret them in light of the patient’s history, clinical presentation and laboratory information’s.
Indian Journal of Medical Biochemistry/Indian journal of medical biochemistry, 2024
Introduction: Evaluation of acid-base status is crucial in critical care settings, with bicarbonate serving as a key indicator of electrolyte distribution and anion deficit. This study explored the challenges and uncertainties surrounding the quantification and stability of bicarbonate levels, crucial for accurate clinical assessments. Methods: The study conducted in the clinical biochemistry laboratory of a tertiary care hospital involves a comparative analysis between serum and arterial bicarbonate levels. We examined serum bicarbonate in 31 patient samples, with concurrently calculated arterial values obtained from blood gas analysis reports of the same patients. Additionally, the stability of serum bicarbonate was assessed at different time intervals. Results: A significant correlation was observed between serum and arterial bicarbonate (r = 0.91), which was reinforced by Bland-Altman analysis. However, the stability assessment revealed a decrease in serum bicarbonate levels at 2 and 4 hours. Conclusion: This study contributes to the exploration of simplified methods for assessing acid-base status, particularly valuable in less-equipped conditions. The findings underscore the necessity for awareness among healthcare professionals regarding the impact of preanalytical variables, particularly uncapped tube storage, on serum bicarbonate levels.