Nicotinic acetylcholine receptors in the nervous system: Structure, distribution and modification in brain pathology (original) (raw)

1989, Neurobiology of Aging

AI-generated Abstract

The paper summarizes the findings from a NATO-sponsored workshop on nicotinic acetylcholine receptors held in 1988, emphasizing their structure, distribution, and roles in brain pathology. It highlights the complexity and diversity of neuronal nicotinic receptors compared to muscular ones, discussing their pharmacological properties and involvement in essential functions such as memory and motor control. The conclusions underline the potential for developing new therapies targeting these receptors for addressing CNS degenerative diseases.

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