Both Triggering and Amplifying Pathways Contribute to Fuel-induced Insulin Secretion in the Absence of Sulfonylurea Receptor-1 in Pancreatic -Cells (original ) (raw )Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y
keith lindley
Diabetes, 2000
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Cooperation between cAMP signalling and sulfonylurea in insulin secretion
Tadao Shibasaki
Diabetes, obesity & metabolism, 2014
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The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells
Heidy Antomarchi
Journal of Biological …, 1987
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ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone
Heidy Antomarchi
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Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels
Peter Drain
AJP: Endocrinology and Metabolism, 2007
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Glucose both inhibits and stimulates insulin secretion from isolated pancreatic islets exposed to maximally effective concentrations of sulfonylureas
S. Lenzen
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C16:0 Sulfatide Inhibits Insulin Secretion in Rat β-Cells by Reducing the Sensitivity of KATP Channels to ATP Inhibition
Maria Blomqvist
Diabetes, 2006
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Sulfonylureas Correct Trafficking Defects of ATP-sensitive Potassium Channels Caused by Mutations in the Sulfonylurea Receptor
Show-ling Shyng
Journal of Biological Chemistry, 2004
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An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action
Diethart Schmid
Cellular and Molecular Life Sciences, 2012
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Overnight Culture Unmasks Glucose-induced Insulin Secretion in Mouse Islets Lacking ATP-sensitive K+ Channels by Improving the Triggering Ca2+ Signal
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ATP-Sensitive K+ Channel-Dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-Type and SUR1-/- Mouse -Cells
Krister Bokvist
Diabetes, 2004
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The antidiabetic sulfonylurea glibenclamide is a potent blocker of the ATP-modulated K+ channel in insulin secreting cells
Heidy Antomarchi
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ATP and Sulfonylurea Linkage in the KATP Channel Solves a Diabetes Puzzler
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Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C
ya tian
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Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice
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Mette Jensen
American Journal of …, 2008
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Khalid Hussain
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A new experimental model of ATP-sensitive K+ channel-independent insulinotropic action of glucose: a permissive role of cAMP for triggering of insulin release from rat pancreatic β-cells
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Characterization of the rat mesangial cell type 2 sulfonylurea receptor
Balàzs Szamosfalvi , Jerry Yee
Kidney International, 1999
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Glucose Stimulates Ca2+ Influx and Insulin Secretion in 2-Week-old beta-Cells Lacking ATP-sensitive K+ Channels
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Metabolic Control in Type 2 Diabetes Is Associated with Sulfonylurea Receptor-1 (SUR-1) but Not with KCNJ11 Polymorphisms
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Role of aryl hydrocarbon receptor nuclear translocator in KATP channel-mediated insulin secretion in INS-1 insulinoma cells
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ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release
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Characterization of the Mouse Sulfonylurea Receptor 1 Promoter and Its Regulation
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ATP-binding without hydrolysis switches sulfonylurea receptor 1 (SUR1) to outward-facing conformations that activate KATP channels
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GLUT2 and glucokinase expression is coordinately regulated by sulfonylurea
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Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene
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Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective
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