Conformationally restricted cationic polyamide analogs of nucleic acids: Design, synthesis, and DNA/RNA binding studies (original) (raw)

α-PNA: A Novel Peptide Nucleic Acid Analogue of DNA

Laurence Wakelin

The Journal of Organic Chemistry, 1997

View PDFchevron_right

Per gamon Peptide Nucleic Acids (PNA): Synthesis, Properties and Potential Applications3 NMR studies of PNA-DNA and PNA-RNA hybrids4 Interactions of DNA binding ligands with PNA-DNA complexes

Digvijay Gahtory

View PDFchevron_right

Hydrophilic and Cell-Penetrable Pyrrolidinyl Peptide Nucleic Acid via Post-synthetic Modification with Hydrophilic Side Chains

Chaturong Suparpprom

Bioconjugate Chemistry, 2017

View PDFchevron_right

Pyrrolidinyl peptide nucleic acid with α/β-peptide backbone: A conformationally constrained PNA with unusual hybridization properties

Tirayut Vilaivan

Http Dx Doi Org 10 4161 Adna 2 2 16340, 2011

View PDFchevron_right

¿Design and Synthesis of Modified Peptide Nucleic Acid (Pnas) with Improved Physico-Chemical Properties for Dna, Rna and Micro Rna Targeting¿

Pramod Thakare

2017

View PDFchevron_right

Synthesis of new building blocks: Towards the analogs of peptide nucleic acids (PNAs)

Prabhat Arya

Tetrahedron Letters, 1998

View PDFchevron_right

Chimeric peptide nucleic acids incorporating (2 S,5 R)-aminoethyl pipecolyl units: synthesis and DNA binding studies

Vaijayanti Kumar

Tetrahedron Letters, 2004

View PDFchevron_right

Peptide Nucleic Acids (PNAs)

Catalina Achim

Wiley Encyclopedia of Chemical Biology, 2007

View PDFchevron_right

Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding

Anna Varizhuk

PloS one, 2015

View PDFchevron_right

Synthesis and nucleic acid binding studies of novel pyrrolidinyl PNA carrying an N-amino-N-methylglycine spacer

Tirayut Vilaivan

Tetrahedron Letters, 2003

View PDFchevron_right

Fmoc/Acyl protecting groups in the synthesis of polyamide (peptide) nucleic acid monomers

Zoltán Timár

Journal of the Chemical Society, Perkin Transactions 1, 2000

View PDFchevron_right

Synthesis and biophysical studies of nucleic acid-binding oligomers

Riyadh Nahi

2016

View PDFchevron_right

Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity

Mauro Adamo

Artificial DNA: PNA & XNA, 2014

View PDFchevron_right

Affinity and kinetic modulation of polyamide-DNA interactions by N -modification of the heterocycles

balaji babu

Biopolymers, 2013

View PDFchevron_right

(α,α-dimethyl)glycyl (dmg) PNAs: achiral PNA analogs that form stronger hybrids with cDNA relative to isosequential RNA

Krishna Ganesh

Artificial DNA, PNA & XNA

View PDFchevron_right

Synthesis and oligodeoxynucleotide binding properties of pyrrolidinyl peptide nucleic acids bearing prolyl-2-aminocyclopentanecarboxylic acid (ACPC) backbones

Polkit Sangvanich

Tetrahedron Letters, 2005

View PDFchevron_right

Peptide Nucleic Acids with a Conformationally Constrained Chiral Cyclohexyl-Derived Backbone

Bengt Nordén

Chemistry - A European Journal, 1997

View PDFchevron_right

(1S,2R/1R,2S)-cis-Cyclopentyl PNAs (cpPNAs) as Constrained PNA Analogues: Synthesis and Evaluation of aeg-cpPNA Chimera and Stereopreferences in Hybridization with DNA/RNA

Krishna Ganesh

The Journal of Organic Chemistry

View PDFchevron_right

Synthesis and DNA/RNA binding properties of conformationally constrained pyrrolidinyl PNA with a tetrahydrofuran backbone deriving from deoxyribose

Tirayut Vilaivan

The Journal of Organic Chemistry, 2015

View PDFchevron_right

Remarkable enhancement of binding affinity of Heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N2-imidazolylpropylguanine and N2-imidazolylpropyl-2-aminoadenine modified oligonucleotides

Dan Cook

Tetrahedron Letters, 1994

View PDFchevron_right

Liquid-phase synthesis of polyamide nucleic acids (PNA)

Christophe Di Giorgio, Nadia Patino

Tetrahedron, 1999

View PDFchevron_right

The synthesis of polyamide nucleic acids using a novel monomethoxytrityl protecting-group strategy

Jochen Knolle

Tetrahedron, 1995

View PDFchevron_right

SYNTHESIS OF DIFFERENT TYPES OF PNAS, CONTAINING CHIRAL PSEUDOPEPTIDE BACKBONE

Tatyana Dzimbova

Trakia Journal of Sciences, 2010

View PDFchevron_right

Novel nucleic acid analogs with a chimeric phosphinate/phosphate backbone; synthesis and biophysical properties

Magda Janicka

Arkivoc, 2004

View PDFchevron_right

Insight into why pyrrolidinyl peptide nucleic acid binding to DNA is more stable than the DNA·DNA duplex

Tirayut Vilaivan, Khatcharin Siriwong

Biochemical and Biophysical Research Communications, 2008

View PDFchevron_right

Synthesis of 2‘-Amino-LNA: A Novel Conformationally Restricted High-Affinity Oligonucleotide Analogue with a Handle

Ravindra Kumar

Journal of Organic Chemistry, 1998

View PDFchevron_right

Synthesis of Novel DNA binding Polyamides to Prevent Cancer relat

Huy Q Nguyen

Huy Nguyen, 2024

View PDFchevron_right

Synthesis and Properties of Aminopropyl Nucleic Acids

Roger Busson, Arthur Van Aerschot

ChemBioChem, 2005

View PDFchevron_right

Synthesis and Application of Functional Nucleic Acids

Daisuke Miyoshi

Journal of Nucleic Acids, 2011

View PDFchevron_right

Peptide Nucleic Acids (PNAs), A Chemical Overview

Andrea Porcheddu

Current Medicinal Chemistry, 2005

View PDFchevron_right

Highly Efficient Synthesis of DNA-Binding Polyamides Using a Convergent Fragment-Based Approach

Paul Cullis

Organic Letters, 2014

View PDFchevron_right