Stimulation of bile output by gastrointestinal hormones following portoenterostomy for biliary atresia (original) (raw)

The study investigates the effects of gastrointestinal hormones secretin and glucagon on bile flow output in pediatric patients who have undergone portoenterostomy for biliary atresia. Data from five patients were collected over various time periods post-surgery, revealing significant increases in bile volume and bicarbonate concentration following secretin infusion in patients with bile flow. The study aims to differentiate functional from structural obstruction in bile flow and assess the impact of these hormones on hepatic excretory function.