original ) (raw )Covalent Linkage Mediates Communication between ACP and TE Domains in Modular Polyketide Synthases
Peter Leadlay
ChemBioChem, 2008
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Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold
Luisa Moretto
Scientific Reports
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Evidence for a Protein-Protein Interaction Motif on an Acyl Carrier Protein Domain from a Modular Polyketide Synthase
Filip Meersman
Chemistry & Biology, 2006
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An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein
Matthew Crump
Chembiochem, 2008
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Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain
Gaurav Shakya
Angewandte Chemie International Edition, 2016
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A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate
Brian Kevany , Katrina Forest
PloS one, 2014
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A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis
Thomas Simpson
Nature Chemical Biology, 2013
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Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase
Kyle Bingham
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Identification and Analysis of the Acyl Carrier Protein (ACP) Docking Site on β-Ketoacyl-ACP Synthase III
Richard Heath
Journal of Biological Chemistry, 2000
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Sulfonyl 3-Alkynyl Pantetheinamides as Mechanism-Based Cross-Linkers of Acyl Carrier Protein Dehydratase
Kara Finzel
Journal of the American Chemical Society, 2013
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Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis
Frank Schulz
Chemistry & Biology, 2015
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X-Ray Crystallographic Studies on Butyryl-ACP Reveal Flexibility of the Structure around a Putative Acyl Chain Binding Site
Anna Roujeinikova , Antoni Slabas
Structure, 2002
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Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria
Ludmilla Morozova-roche
Acta Crystallographica Section D Biological Crystallography, 2012
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The Structure of Docking Domains in Modular Polyketide Synthases
Peter Leadlay
Chemistry & Biology, 2003
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Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase
Andrew Worthington
Bioorganic & Medicinal Chemistry Letters, 2008
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Reprogramming Acyl Carrier Protein Interactions of an Acyl-CoA Promiscuous trans-Acyltransferase
Gavin P Williams
Chemistry & Biology, 2014
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Catalytic self-acylation of type II polyketide synthase acyl carrier proteins
Tom Simpson
Chemistry & Biology, 1998
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Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production
Edward Baidoo
ACS synthetic biology, 2016
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A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation
Ravi pal
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2018
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Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates
Luisa Moretto
Chemical communications (Cambridge, England), 2017
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Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites
Jasbir Seehra
Structure, 2000
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Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2)
Christopher Williams , Russell Cox
Journal of Molecular Biology, 2009
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Crystal Structure of an Acyl-ACP Dehydrogenase from the FK520 Polyketide Biosynthetic Pathway: Insights into Extender Unit Biosynthesis
Robert Stroud
Journal of Molecular Biology, 2003
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Structure mediation in substrate binding and post-translational processing of penicillin acylases: Information from mutant structures of K luyvera citrophila penicillin G acylase
Nishant Kumar Varshney
Protein Science, 2015
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Effect of Acylation on the Structure of the Acyl Carrier Protein P
Sung Jean Park
Journal of the Korean Magnetic Resonance Society, 2015
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Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein
Tom Simpson
Chem. Sci., 2016
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Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne Biosynthesis
J. Lescar
Journal of Biological Chemistry, 2012
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