Dynamic Tuning of T Cell Reactivity by Self-Peptide-Major Histocompatibility Complex Ligands
Philip Wong
Journal of Experimental Medicine, 2001
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T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions
Pierre Rizkallah
Journal of Biological Chemistry, 2014
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Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
stephanie gras
Proceedings of The National Academy of Sciences, 2010
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Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset Commitment
Jia-huai Wang
Frontiers in immunology, 2013
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Structure of an Autoimmune T Cell Receptor Complexed with Class II Peptide-MHCInsights into MHC Bias and Antigen Specificity
Erin Adams
Immunity, 2005
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MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition
Sandra Reichstetter
1999
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αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities
Changwan Hong
Immunity, 2012
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MOLECULAR INTERACTIONS MEDIATING T CELL ANTIGEN RECOGNITION
Anton Merwe
Annual Review of Immunology, 2003
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The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
Anthony Purcell
Nature Immunology, 2005
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T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation
Balbino Alarcón
PLoS ONE, 2008
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Divergent Changes in the Sensitivity of Maturing T Cells to Structurally Related Ligands Underlies Formation of a Useful T Cell Repertoire
Bruno Lucas
Immunity, 1999
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How the T Cell Receptor Sees Antigen—A Structural View
Erin Adams
Cell, 2005
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A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection
Balbino Alarcón
Proceedings of the National Academy of Sciences of the United States of America, 2006
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The same self-peptide selects conventional and regulatory CD4+ T cells with identical antigen receptors
Michal Seweryn
Nature Communications, 2014
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Role of Self-Major Histocompatibility Complex/Peptide Ligands in Selection and Maintenance of a Diverse T Cell Repertoire
DONG-SUP LEE
Immunologic Research, 2000
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Point mutations in the β chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I\peptide complex over a broad interface area
Sebastian Joyce
Molecular Immunology, 1998
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Structural Basis of Plasticity In T Cell Receptor Recognition of a Self Peptide-MHC Antigen
Mingdong Huang
Science, 1998
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Stage-dependent reactivity of thymocytes to self-peptide–MHC complexes
Jianzhu Chen
Proceedings of the National Academy of Sciences, 2007
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Specificity to a T Cell Receptor with the Same Similarities with an Antigenic Peptide: Complexed d MHC-I Molecule H-2D Antibodies Directed Against the
Jay Berzofsky
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Analysis of the Expression of Peptide-Major Histocompatibility Complexes Using High Affinity Soluble Divalent T Cell Receptors
Ursula Utz
Journal of Experimental Medicine, 1997
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Conserved T-cell receptor class II major histocompatibility complex contact detected in a T-lymphocyte population
Ming-Zong Lai
Immunology, 1998
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Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling
Luigi Racioppi
Journal of Experimental Medicine, 1993
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The T-cell receptor is not hardwired to engage MHC ligands
Stephen Holland
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Predicting interactions between T cell receptors and MHC-peptide complexes
Kirsten Roomp
Molecular Immunology, 2011
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Quantitative Analysis of the T Cell Repertoire Selected by a Single Peptide-Major Histocompatibility Complex
E. Beaudoing
Journal of Experimental Medicine, 1998
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Flexibility in T-cell receptor ligand repertoires depends on MHC and T-cell receptor clonotype
Krista van Meijgaarden
Immunology, 1997
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Immunology: How Do T Cells Recognize Antigen?
Anton Merwe
Current Biology, 2005
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T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen
Edwin Stevex
Journal of Experimental Medicine, 1993
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Antibodies Directed Against the MHC-I Molecule H-2Dd Complexed with an Antigenic Peptide: Similarities to a T Cell Receptor with the Same Specificity
David Margulies
The Journal of Immunology, 2000
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