Enzymes and metabolites of cysteine metabolism in nonhepatic tissues of rats show little response to changes in dietary protein or sulfur amino acid levels (original) (raw)

Mechanisms involved in the regulation of key enzymes of cysteine metabolism in rat liver in vivo

Martha Stipanuk

The American journal of physiology, 1999

View PDFchevron_right

Cysteine is the metabolic signal responsible for dietary regulation of hepatic cysteine dioxygenase and glutamate cysteine ligase in intact rats

Martha Stipanuk

The Journal of nutrition, 2003

View PDFchevron_right

Rats fed a low protein diet supplemented with sulfur amino acids have increased cysteine dioxygenase activity and increased taurine production in hepatocytes

Martha Stipanuk

The Journal of nutrition, 1995

View PDFchevron_right

5th Amino Acid Assessment Workshop Mammalian Cysteine Metabolism: New Insights into Regulation of Cysteine Metabolism 1,2

Huynh Nguyen Truc Phuong

View PDFchevron_right

Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism

Martha Stipanuk

The Journal of nutrition, 2006

View PDFchevron_right

Effects of nonsulfur and sulfur amino acids on the regulation of hepatic enzymes of cysteine metabolism

Martha Stipanuk

American Journal of Physiology-Endocrinology and Metabolism, 1999

View PDFchevron_right

Role of the Liver in Regulation of Body Cysteine and Taurine Levels: A Brief Review

Martha Stipanuk

Neurochemical Research, 2004

View PDFchevron_right

Cysteine Is the Metabolic Signal Responsible for Dietary Regulation of Hepatic Cysteine Dioxygenase and Glutamate Cysteine Ligase in Intact Rats1

Martha Stipanuk

2000

View PDFchevron_right

Cysteine regulates expression of cysteine dioxygenase and γ-glutamylcysteine synthetase in cultured rat hepatocytes

Martha Stipanuk

American Journal of Physiology-Endocrinology and Metabolism, 2001

View PDFchevron_right

Effect of excess dietary methionine on the catabolism of cysteine in rats

Martha Stipanuk

The Journal of nutrition, 1979

View PDFchevron_right

The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H2S/HS−Production and Evidence of Pancreatic and Lung Toxicity

Martha Stipanuk

Antioxidants & Redox Signaling, 2013

View PDFchevron_right

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

Martha Stipanuk

American Journal of Physiology-Endocrinology and Metabolism, 2011

View PDFchevron_right

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels

Martha Stipanuk

Amino Acids, 2009

View PDFchevron_right

Methionine and Cysteine Affect Glutathione Level, Glutathione-Related Enzyme Activities and the Expression of Glutathione S-Transferase Isozymes in Rat Hepatocytes

Chong-kuei Lii

The Journal of Nutrition, 1997

View PDFchevron_right

Liver intracellular L-cysteine concentration is maintained after inhibition of the trans-sulfuration pathway by propargylglycine in rats

Juan Sastre

British Journal of Nutrition, 1997

View PDFchevron_right

Oxidative stress induces a reversible flux of cysteine from tissues to blood in vivo in the rat

Daniela Giustarini

FEBS Journal, 2009

View PDFchevron_right

In vivo studies of cysteine metabolism. Use of D-cysteinesulfinate, a novel cysteinesulfinate decarboxylase inhibitor, to probe taurine and pyruvate synthesis

Owen Griffith

Journal of Biological Chemistry, 1988

View PDFchevron_right

Dietary supplementation with cysteine prodrugs selectively restores tissue glutathione levels and redox status in protein-malnourished mice1 1Supported in part by the OARDC Hatch Fund to T.M.B., National Institutes of Health Grant NS38315 to T.M.B

Gary Stoner

The Journal of Nutritional Biochemistry, 2002

View PDFchevron_right

Methionine-Adequate Cysteine-Free Diet Does Not Limit Erythrocyte Glutathione Synthesis in Young Healthy Adult Men

Paul Pencharz

Journal of Nutrition, 2008

View PDFchevron_right

Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans

Youngja Park

Nutrition, 2011

View PDFchevron_right

Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells

Martha Stipanuk

AJP: Endocrinology and Metabolism, 2007

View PDFchevron_right

First-pass splanchnic metabolism of dietary cysteine in weanling pigs

Jeremy Cottrell

Journal of Animal Science, 2011

View PDFchevron_right

Excretion of cysteine and gamma-glutamylcysteine moieties in human and experimental animal gamma-glutamyl transpeptidase deficiency

Owen Griffith

Proceedings of the National Academy of Sciences, 1980

View PDFchevron_right

Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin–26 S proteasome system in the living rat

Martha Stipanuk

Biochemical Journal, 2006

View PDFchevron_right

Effects of a Low-Protein Diet on Plasma Amino Acid and Homocysteine Levels and Oxidative Status in Rats

Guilherme V Portari

Annals of Nutrition and Metabolism, 2009

View PDFchevron_right

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

Martha Stipanuk

Journal of Inherited Metabolic Disease, 2010

View PDFchevron_right

The In Vivo Sparing of Methionine by Cysteine in Sulfur Amino Acid Requirements in Animal Models and Adult Humans

Paul Pencharz

The Journal of Nutrition, 2006

View PDFchevron_right

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

Martha Stipanuk

Amino Acids, 2014

View PDFchevron_right

Cysteine and Glutathione Levels in Developing Rat Kidney and Liver

John Foreman

Pediatric Research, 1987

View PDFchevron_right

Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice

Martha Stipanuk

Annals of the New York Academy of Sciences, 2016

View PDFchevron_right

The effect of cysteine on the altered expression of class α and μ glutathione S-transferase genes in the rat liver during protein–calorie malnutrition

Yoon Gyoon Kim

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2000

View PDFchevron_right

Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase

Martha Stipanuk

AJP: Endocrinology and Metabolism, 2012

View PDFchevron_right

Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate–cysteine ligase subunits

Martha Stipanuk

Amino Acids, 2014

View PDFchevron_right

Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase

Helga Refsum

The Journal of Lipid Research, 2011

View PDFchevron_right

The ubiquitin-proteasome system is responsible for cysteine-responsive regulation of cysteine dioxygenase concentration in liver

Martha Stipanuk

AJP: Endocrinology and Metabolism, 2003

View PDFchevron_right