Comparing the Effect of Facial Compression Bandage to That of Systemic Dexamethasone on Postsurgical Sequels after Extraction of Impacted Mandibular Third Molars: A Split-mouth Randomized Clinical Trial (original) (raw)
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Journal of Dental and Craniofacial Research
Objective of this study was aimed to compare the therapeutic effects of 8 mg dexamethasone intramuscular administered pre-operatively vs post-operatively after the surgical extraction of impacted mandibular third molars, in Al-Qurayyat, Saudi Arabia, population. One hundred and fifty patients who visited the Department of Oral and Maxillofacial Surgery of Gurayat specialized dental center, Al-Qurayyat, Saudi Arabia, were included in the study. The study was conducted from February 2018 to August 2018. 150 patients constituted the study and were randomly divided into two groups. Group A received 8 mg dexamethasone (intramuscular) 1hr pre-operatively. Group B received 8 mg dexamethasone (intramuscular) immediately after the surgery. According to the gender there were 81(54%) males and 69 (46%) females, in both the groups combined. Males to females' ratio was 1.17: 1 in this study. Post-operative 1 st and 3 rd day follow-up showed that there was a significant difference between the two groups in terms of swelling and mouth opening (P=0.000). Overall, Group A showed much better results as far as the post-operative swelling and mouth opening was concerned. There was no statistical difference in the scores when the post-operative pain was evaluated on 1 st , 3 rd and 7 th day (P=0.679, P=0.755, P=0.202). The depth, angulation and the position of the tooth did not affect the study in terms of significance (P=0.626, P=0.874, P=1.000). It was concluded that preoperative administration of single dose of dexamethasone intramuscularly was more effective than the postoperative period, in reducing the swelling and trismus.
2016
OBJECTIVE To evaluate the efficacy of immediate intramasseteric injection of dexamethasone on postoperative oedema. METHODS The prospective study was conducted at the Department of Oral and Maxillofacial Surgery, Ankara University, Ankara, Turkey, in July 2012, and comprised patients aged 15-32 years who presented for the removal of bilateral vertical impacted mandibular third molar teeth.The right and left impacted third molars of each patient were randomly allocated into study and control groups. The impacted teeth in the study group were extracted with surgical bone removal, and 2ml of 8mg/2ml dexamethasone was injected into the ipsilateral masseter muscle immediately after suturing.In the control group, dexamethasone was replaced with 2ml of sterile saline solution. Postoperative facial oedema was measured with a tape scale by calculating the distance between several facial landmarks on postoperative day 2. SPSS 15 was used for data analysis. RESULTS The mean age of 20 patients ...
Journal of Health Sciences & Research
Aims and objectives: To understand the benefits of dexamethasone and compare the effects of submucosal vs intramuscular (IM) administration of dexamethasone in reducing postoperative sequelae following impacted mandibular third molar surgery. Materials and methods: The study was conducted on 90 patients, who were divided into three groups of 30 each. The two experimental groups were given dexamethasone 4 mg submucosally or intramuscularly (preoperatively), and the control group did not receive any form of corticosteroid. Measurements of facial swelling and maximal interincisal distance were made preoperatively and on the 1st, 3rd, and 7th postoperative days. Pain was evaluated from patients' response to visual analog scale and recording the number of rescue analgesic tablets taken at the end of the 7th postoperative day. Results: Both dexamethasone groups showed a significant reduction in pain, swelling, and trismus as compared with the control group at all intervals. There was a statistically significant reduction in magnitude of swelling in the submucosal dexamethasone group as compared with the IM dexamethasone group on the 1st postoperative day, but there was no significant difference among two experimental groups at other times and their effects were comparable for all variables. Conclusion: Dexamethasone 4 mg is an effective therapeutic strategy for reducing postoperative sequelae following surgical removal of impacted third molars and submucosal dexamethasone is an effective alternative to dexamethasone given systemically.
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
Introduction: The surgical removal of impacted mandibular third molars is an invasive procedure that involves extensive tissue trauma and a considerable postoperative inflammatory response. Although the inflammatory process is necessary for healing when exacerbated it may cause pain, swelling and limited mouth opening. Corticosteroids are among the most widely employed pre-operative medication administered for the control of such complications. Objective: To compare the effects of single dose of pre-operative Injection Dexamethasone versus Injection Methylprednisolone via Intramuscular or Submucosal route for controlling the post-operative pain, swelling and limited mouth opening in the removal of impacted mandibular third molars. Material and Method:. The present study was conducted on 40 healthy adult patients with bilaterally symmetrical impacted mandibular third molar, reporting to the Department of oral and Maxillofacial Surgery of Guru Nanak Dev Dental College and Research Ins...
Impacted Mandibular Third Molar Surgery
The Professional Medical Journal, 2014
Objective: The objective of this study was to evaluate the therapeutic effect of dexamethasone in post-operative edema and trismus after impacted third molar surgery. Materials & Methods: It was a prospective randomized control study carried in Department of Oral & Maxillofacial surgery, BADC, Larkana from March 2012 to Feb 2013. Patients age between 20-45 years of either gender; unilateral mandibular impacted third molars (right or left) were included. Patients divided in two groups by using random allocation number. Patients in Group-A were given intramuscular 8 mg dexamethasone 1 hour before surgery and four tablets (2mg) dexamethasone orally immediate postoperatively and 24 hours after surgery. The facial swelling was checked before surgery, after 24 hours (1st day), after 48 hours (2nd day), after 72 hours (3rd day) and on 7th postoperative day Inter-incisor distance was checked on every follow up. Data was analyzed by SPSS version 17. Mean and standard deviation was calculated...
Nepal Journal of Health Sciences
Introduction: Third molar surgery is one of the most common procedures performed by dental surgeons in clinical practice, where postoperative sequelae like pain, trismus, and swelling are often encountered. Thus, in this study, we compared medications employed to reduce such complications. Objective: To compare the effect of two different doses (4 and 8 mg) of dexamethasone in the control of swelling and trismus after the surgical extraction of mandibular impacted third molars. Methods: An experimental study consisted of twenty-seven (27) healthy adult patients of both genders with bilateral impacted lower third molars, where surgical extraction was indicated, 4 mg and 8 mg of dexamethasone were given orally to the patients 1 hour before the surgical procedure at both the surgeries. The swelling was recorded by measuring the length of 3 facial planes using a measuring tape. Trismus was evaluated by measuring the maximum interincisal distance. Recording of facial swelling and maximum...
National Journal of Maxillofacial Surgery, 2020
Objectives: A randomized prospective double-blind study was conducted to determine the efficacy of sub-mucosal local infiltration vs. intravenous dexamethasone in reducing postoperative pain, swelling and trismus after surgical removal of impacted mandibular third molars. Materials and Methods: Forty five patients were included in the study and were randomly divided into three groups. Each group consisted of 15 patients for which the first and second groups were given 8 mg of dexamethasone intrlesionally & intravenously respectively, at 30 minutes prior to surgery; the third group served as control. Duration of facial swelling was evaluated subjectively by the patients themselves. Severity of postoperative pain was quantified by counting the number of analgesics taken by the patients during and after surgery (six subsequent days). Postoperative trismus was determined by measuring the maximum incisal opening before surgery and on the seventh day. Results: Results showed that duration of postoperative edema was almost the same in the three test groups. During surgery, the intravenous dexamethasone group showed a significantly lesser pain than the other two groups; the intralesional dexamethasone group showed less marked pain than the control group. Additionally, patients who had taken steroids had a marked increase in the incisal opening postoperatively over the control group. Trismus was significantly reduced in the methylprednisolone group as compared to the dexamethasone group. Conclusion: It is concluded that both preoperative local infiltration and intravenous administration of dexamethasone significantly reduced postoperative pain and trismus after surgical removal of mandibular third molars. An intravenous dexamethasone is more effective in reducing postoperative inflammatory sequelae than its intralesional route.
Effect of Dexamathasone in Surgical Extraction of Mandibular Impacted Third Molar
Journal of Pharmaceutical Research International, 2021
Objective: The objective of this study was to determine the role of dexamethasone in mandibular third molar surgical extraction. Methodology: This cross sectional study was conducted in Oral & Maxillofacial surgery department, Liaquat University of Medical & Health sciences Hyderabad / Jamshoro. 50 cases were included in this study by using simple random sampling technique. All patients were divided into two groups. Patients in Group-A were given dexamethasone (DM)8 mg intramuscularly (IM) before surgery and 4 mg 24 hours after surgery and Augmentin tablet 625mg Q12 hrs. and Brufen 400 mg Q8 hrs. and patients in group-B were given Augmentin 625 mg BD and Brufen 400 mg TDS post operatively only. The facial swelling was checked before and after surgery.All information was collected and entered in a proforma. Results: The study sample was consisted of 62% men and 38% women. Mean age was 26.9±6.64.The mean preoperative swelling was 109.20 ± 1.190 mm in control group and 109.44 ± 1.083 ...
Egyptian dental journal, 2019
Purpose: The aim of the current study was to compare the efficacy of dexamethasone injection submucosally, intra-masseteric and intramuscular in surgical removal of mandibular third molars on post-operative swelling, mouth opening and pain. Patients and Methods: forty five patients with impacted mandibular third molars were selected to undergo surgical removal of mandibular third molars. Patients were randomly divided into three groups of fifteen each. Group I, taking sub-mucosal dexamethasone injection, Group II, taking Intra-masseteric dexamethasone injection and Group III, taking intramuscular dexamethasone injection, all patients were injected pre-operatively Assessment of swelling, mouth opening, and pain was done at intervals of 1st, 3rd, and 7th post-operative days. Results: our study showed no statistically significant difference between mean MMO as well as VAS in Group I and II; both showed statistically significant higher mean MMO and VAS than Group III. Significant reduction in pain and swelling in both sub-mucosal, intra-masseteric and intra-muscular but a greater immediate effect on trismus was seen in sub-mucosal and intramasseteric routes Conclusion: It can be concluded that pre-operative dexamethasone injection is an effective pharmacological agent to reduce post-surgical third molar removal sequelae such as pain, swelling and trismus.
INDIAN JOURNAL OF APPLIED RESEARCH, 2023
This double-blind, split-mouth, and randomized study was aimed to compare the efficacy of dexamethasone and ketorolac tromethamine, through the evaluation of pain, edema, and limitation of mouth opening. Thirty-four individuals aged 18-26 years, having bilateral mandibular third molars, in a similar position, were selected. Two different surgical procedures were performed on the same individual by the single surgeon. For an extraction, the individual received 1 capsule of 10 mg ketorolac tromethamine 1 h before surgery and every 8 h for 2 days. For the extraction of the contralateral side, the individual received 1 capsule of 8 mg dexamethasone 1 h before surgery and 1 placebo capsule every 8 h for 2 days. Sodium metamizol, 500 mg, was given as rescue medication in postoperative. Pain was assessed by the Visual Box Scale-11 points (BS-11) at 24 h postoperative. Edema (metric measurement) and the maximum mouth opening (interincisal) were recorded in the pre-operative, 24 h, 48 h, 72 h and 7 days postoperatively. The results showed that both therapeutic treatments used were effective in the postoperative, and there were no statistically significant differences between the groups for the pain and edema variables. However, for the limitation of mouth opening, 24 h and 7 days postoperatively, the dexamethasone group had a lower limitation of mouth opening, behaving better than the ketorolac for this variable in these periods. Due also to the higher margin of safety, the use of dexamethasone as a single dose becomes a more suitable alternative for use in routine surgical extractions of third molars.