Structural Basis for Domain–Domain Communication in a Protein Tyrosine Kinase, the C-terminal Src Kinase (original) (raw)
Probing the Communication between the Regulatory and Catalytic Domains of a Protein Tyrosine Kinase, Csk
Sungsoo Lee
Biochemistry, 2005
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Identification of N-terminal lobe motifs that determine the kinase activity of the catalytic domains and regulatory strategies of Src and Csk protein tyrosine kinases
Alex Brown
2009
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Dynamic Coupling between the SH2 and SH3 Domains of c-Src and Hck Underlies Their Inactivation by C-Terminal Tyrosine Phosphorylation
Benoit Roux
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Dissection of the catalytic and regulatory structure-function relationships of Csk protein tyrosine kinase
Gongqin Sun
Frontiers in Cell and Developmental Biology
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The Tyrosine Kinase Csk Dimerizes through Its SH3 Domain
Patrick Visperas
PLoS ONE, 2009
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Functional Diversity of Csk, Chk, and Src SH2 Domains due to a Single Residue Variation
Keykavous Parang
Journal of Biological Chemistry, 2005
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SH2 Domain-Mediated Interaction of Inhibitory Protein Tyrosine Kinase Csk with Protein Tyrosine Phosphatase-HSCF
Schickwann Tsai
Molecular and Cellular Biology, 2001
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Anatomy of a Structural Pathway for Activation of the Catalytic Domain of Src Kinase Hck
Benoit Roux
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Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase
Natalie Gunn, Renwick Dobson
Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 2011
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Intramolecular Regulatory Interactions in the Src Family Kinase Hck Probed by Mutagenesis of a Conserved Tryptophan Residue
Margaret Porter-Scott
Journal of Biological Chemistry, 1998
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Solution studies of the SH2 domain from the fyn tyrosine kinase: secondary structure, backbone dynamics and protein association
Stephen E Harding
European Biophysics Journal, 1996
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Molecular dissection of the interaction between the SH3 domain and the SH2-Kinase Linker region in PTK6
Han Kim
Biochemical and biophysical research communications, 2007
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Structural biology of protein tyrosine kinases
Sandra Cowan-jacob
Cellular and Molecular Life Sciences, 2006
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A novel, specific interaction involving the Csk SH3 domain and its natural ligand
Alexander Shekhtman
2001
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Identification of csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure
Mauno Vihinen
1997
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Structural biology contributions to tyrosine kinase drug discovery
Sandra Cowan-jacob
Current Opinion in Cell Biology, 2009
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The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity
Anthony Day
Structure, 1997
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C-terminal Src Kinase-homologous Kinase (CHK), a Unique Inhibitor Inactivating Multiple Active Conformations of Src Family Tyrosine Kinases
Nicholas Williamson
Journal of Biological Chemistry, 2006
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Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases
Ryan Mills
Growth Factors, 2010
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Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk‒Src homology 3 domain
Kjetil Taskén
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Binding, Domain Orientation, and Dynamics of the Lck SH3−SH2 Domain Pair and Comparison with Other Src-Family Kinases †
Paul Rosch
Biochemistry, 2005
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Phosphorylation Driven Motions in the COOH-terminal Src Kinase, Csk, Revealed Through Enhanced Hydrogen–Deuterium Exchange and Mass Spectrometry (DXMS)
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Journal of Molecular Biology, 2002
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Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase
Nguyen Nam
Proceedings of The National Academy of Sciences, 2003
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Structural Modes of Stabilization of Permissive Phosphorylation Sites in Protein Kinases: Distinct Strategies in Ser/Thr and Tyr Kinases
Narayanaswamy Srinivasan
Journal of Molecular Biology, 2004
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Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn
Govind Panchamoorthy
Molecular and Cellular Biology, 1994
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Substrate and Docking Interactions in Serine/Threonine Protein Kinases
Radha Akella
Chemical Reviews, 2007
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Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism
Juan Aguilar Alvarado
Journal of Biological Chemistry, 2010
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Determination of the solution structure of the SH3 domain of human p56 Lck tyrosine kinase
Hidekazu Hiroaki
Journal of Biomolecular NMR, 1996
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