Spirometry and volumetric capnography in lung function assessment of obese and normal-weight individuals without asthma (original) (raw)
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Evaluation of Pulmonary Function in Adults with Grade III Obesity
Health, 2017
Pulmonary function studies in obese individuals have alerted the pathophysiological changes due to weight gain. However, these changes are not fully explained yet. Objective: To evaluate and analyze the pulmonary function of obese adults in the city of Manaus (AM, Brazil) and to correlate the parameters of spirometry with weight and BMI. Method: A descriptive cross-sectional study, in which pulmonary function of 22 adults with grade III obesity was evaluated pre and post bronchodilator administration, performed at the Adriano Jorge Hospital Foundation-FHAJ. Results: Of the 22 patients evaluated, 6 were male and 16 were female; mean age was 37.1 ± 7.4 years, with a weight of 134.2 ± 28.6 kg and a BMI of 51.1 ± 9.4 kg/m 2 , corresponding to grade III obesity. Spirometry showed a reduction in values obtained from Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1) and Peak Expiratory Flow (PEF) in relation to those predicted, with 23% of restrictive disorders. There were negative correlations between BMI and PEF, weight and FVC, weight and PEF. The P value for correlation of weight and FEV1 is not statistically significant. Conclusion: Restrictive and obstructive disorders are prevalent in the population with grade III obesity. Correlations between pulmonary function and BMI/weight were negative for this specific population.
Lung function in the absence of respiratory symptoms in overweight children and adolescents
Jornal Brasileiro de Pneumologia, 2014
Objective: To describe lung function findings in overweight children and adolescents without respiratory disease. Methods: This was a cross-sectional study involving male and female overweight children and adolescents in the 8-18 year age bracket, without respiratory disease. All of the participants underwent anthropometric assessment, chest X-ray, pulse oximetry, spirometry, and lung volume measurements. Individuals with respiratory disease were excluded, as were those who were smokers, those with abnormal chest X-rays, and those with an SpO 2 ≤ 92%. Waist circumference was measured in centimeters. The body mass index-for-age Z score for boys and girls was used in order to classify the individuals as overweight, obese, or severely obese. Lung function variables were expressed in percentage of the predicted value and were correlated with the anthropometric indices. Results: We included 59 individuals (30 males and 29 females). The mean age was 11.7 ± 2.7 years. Lung function was normal in 21 individuals (35.6%). Of the 38 remaining individuals, 19 (32.2%), 15 (25.4%), and 4 (6.7%) presented with obstructive, restrictive, and mixed ventilatory disorder, respectively. The bronchodilator response was positive in 15 individuals (25.4%), and TLC measurements revealed that all of the individuals with reduced VC had restrictive ventilatory disorder. There were significant negative correlations between the anthropometric indices and the Tiffeneau index in the individuals with mixed ventilatory disorder. Conclusions: Lung function was abnormal in approximately 65% of the individuals evaluated here, all of whom were overweight. Obstructive ventilatory disorder and positive bronchodilator response predominated.
BMC pulmonary medicine, 2014
There is no consensus regarding obesity repercussions for lung function in children and adolescents. Therefore, the aim of the study was to determine whether obesity is associated with poor physical conditioning and damaged lung function in children and adolescents, and to correlate lung function with six-minute walk test (6MWT) results. This cross-sectional study included 38 obese subjects of both sexes, ranging between 5 and 17 years of age, as well as 56 control subjects paired by sex and age for the 6MWT, and 39 subjects for spirometry. Subjects performed spirometry according to the guidelines of the American Thoracic Society (ATS) and the European Respiratory Society. The obese group repeated spirometry after receiving bronchodilator (BD) treatments. Physical performance was evaluated via the 6MWT according to ATS guidelines. The obese group demonstrated lower forced expiratory volumes in the first second compared with the control group based on forced vital capacity indices (p...
Evaluation of Dynamic Pulmonary Function in Obese Individuals
TAJ: Journal of Teachers Association
Introduction: Obesity is becoming a major health hazard in developed and developing countries. Besides the well-known complication like Diabetes mellitus, hypertension. ischemic heart disease, obesity can affect thorax, diaphragm, abdominal muscles, thereby resulting in altered pulmonary functions. Objective: To evaluate the effects of obesity on lung functions Methods: We studied 208 adults of both sex with the age range of 18 to 60. 104 obese subjects were taken as test group (BMI ≥ 25 Kg/m 2) & 104 non obese individuals (BMT 18.5-24.9 Kg/m 2) as control group. Spirometry was performed by using computerized spirometer. Data were expressed as mean & standard deviations. Data were analysed by the help of SPSS version-16. non pair student's 't' test (P values ≤ .05 were considered significant) Pearson correlation analysis & multiple linear regression tests were applied. Results: FVC% (mean & standard deviation), in obese group (Group A) and non obese group (Group B) were 73.42±8.24, 84.05±5.94 respectively. FEV1% (mean & standard deviation), in obese group (Group A) and non obese group (Group B) were 74.65±7.29. 84.22±5.95 respectively. FEV1/FVC% (mean & standard deviation), in obese group (Group A) and non obese group (Group B) were 101.30±9.87, 99.57±11.50 respectively. PEF% (mean & standard deviation), in obese group (Group A) and non obese group (Group B) were 65.98±14.21. 93.53±13.21 respectively. There are statistically significant differences of spirometry results in absolute values and in percentage predicted between two groups, except FEV1/FVC. There were also significant negative correlation between obesity indices (BMI. WC) and spirometric variables except FEV1/FVC%. Conclusion: Obesity independently affects pulmonary functions.
Sao Paulo medical journal = Revista paulista de medicina, 2018
Excess trunk body fat in obese individuals influences respiratory physiological function. The aims of this study were to compare volumetric capnography findings (VCap) between severely obese patients and normal-weight subjects and to assess whether there is any association between neck circumference (NC), waist-hip ratio (WHR) and VCap among grade III obese individuals. Analytical observational case-matched cross-sectional study, University of Campinas. This cross-sectional study compared VCap variables between 60 stage III obese patients and 60 normal-weight individuals. In comparison with the normal-weight group, obese patients presented higher alveolar minute volume (8.92 ± 4.94 versus 6.09 ± 2.2; P = < 0.0001), CO2 production (278 ± 91.0 versus 209 ± 60.23; P < 0.0001), expiratory tidal volume (807 ± 365 versus 624 ± 202; P = 0.005), CO2 production per breath (21.1 ± 9.7 versus 16.7 ± 6.16; P = 0.010) and peak expiratory flow (30.9 ± 11.9 versus 25.5 ± 9.13; P = 0.004). Th...
Small airway function in obese individuals with self-reported asthma
ERJ Open Research, 2020
Diagnosis of asthma in obese individuals frequently relies on clinical history, as airflow by spirometry may remain normal. This study hypothesised that obese subjects with self-reported asthma and normal spirometry will demonstrate distinct clinical characteristics, metabolic comorbidities and enhanced small airway dysfunction as compared with healthy obese subjects.Spirometry, plethysmography and oscillometry data pre/post-bronchodilator were obtained in 357 obese subjects in three groups as follows: no asthma group (n=180), self-reported asthma normal spirometry group (n=126), and asthma obstructed spirometry group (n=51). To assess the effects of obesity related to reduced lung volume, oscillometry measurements were repeated during a voluntary inflation to predicted functional residual capacity (FRC).Dyspnoea was equally prevalent in all groups. In contrast, cough, wheeze and metabolic comorbidities were more frequent in the asthma normal spirometry and asthma obstructed spirome...
Saudi Journal of Nursing and Health Care, 2022
The body mass index (BMI) is commonly used in the assessment of obesity and overweight; however, its use in the diagnosis of adverse effects of obesity is questioned. This study aims to explore the agreement between the BMI and the calculated body fat percentage (BF%) in detecting obesity-induced ventilatory abnormalities. We carried out a cross-sectional study on a random sample of 150 healthy male students, aged 17 to 25, with a mean age of 20.8 ± 2.6 years. We measured the BMI, BF%, and pulmonary function of each participant. The students were classified into overweight-obese and normal groups based on the BMI and the BF% results. The Chi-square test was performed to analyze differences between the groups. About one-fifth of all participants had a fat mass ≥ 20%, among which 90% fulfilled the BMI definition of overweight and obesity (p < 0.05). The comparison between the two BF% groups showed that 20% of the overweight-obese group had a significant reduction in FEV1 (p= 0.025,...
Impact of obesity on peak expiratory flow rate in different age groups
Background: Obesity is a state of excess adipose tissue mass. As adipose tissue accumulates in excess amounts a variety of adaptations/alterations in cardiorespiratory structure and function occur even in the absence of co-morbidities. The pulmonary disorders due to obesity results in increased mortality and morbidity. So, the study was to examine the effect of obesity on Peak Expiratory Flow Rate in different age groups. Methods: 100 Healthy males with BMI 30 kg/m 2 were classified as obese and divided into three groups depending upon their age. 100 Healthy males with BMI of 18.50–24.99 kg/m 2 were taken as controls. Anthropometric parameters were recorded and Body mass index was derived. Peak Expiratory Flow Rate (PEFR) were recorded on a computerized spirometer. ANOVA was used for multiple group comparisons and student's t-test for two group's comparison. Pearson's correlation coefficient was used to measure the relationship between the measurements. Results: In our study PEFR showed a significant decrease in obese subjects compared to non-obese subjects. There was statistically significant decrease in PEFR in obese subjects compared to non-obese subjects in all groups. Study shows the correlation between body mass index and PEFR and BMI which showed a statistically significant negative correlation. Conclusion: In our study BMI had an inverse relationship with PEFR in obese when compared to the normal weight subjects. Thus it is evident from the present study that obesity significantly affects the pulmonary functions which may give rise to long term complications and may lead to early morbidity and mortality.
The Effect of Body Mass Index on Spirometric Parameters in Children with Asthma
Medical Archives, 2016
Aim: Asthma and obesity represent one of the most crucial public and health problems of modern society that frequently begin in childhood and have some mutual elements of risk. Abdominal distribution of connective tissue is important determinant which brings to decrease of lungs function. Multiple influence of overweight on function of the lungs would clearly manifest over reduction of forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC). Method: Examining was conducted at Pediatric Clinic of University Clinical Hospital Tuzla during the year 2013/2014. Research included 60 children with diagnosed asthma who were in relation to BMI were divided in 3 groups. The first group was children with BMI ranging from 5 to 85 percentile, the second were children with 85 to 95 percentile and the third was 95 percentile. By prospective study, compared identical pulmonary variable for all three age group of asthma patients were analyzed, the children with normal body mass a well as the overweight and the obese. Results: At the beginning of testing, the frequency of normal spirometric findings was significantly lower in the obese group in comparison with other two observed groups (p<0,05). The only cases of mixed and restrictive disorder of ventilation were registered in the obese group of tested at the beginning of the examined (p<r0,001). Conclusion: When being compared the values of spirometric parameters before and after the research, the only significant difference was in the obese group, the values after tests were significantly higher, with the exception of relation FEV1/FVC, that had the same distribution of values before and after research. However, the group with normal body mass and overweight, had all the spirometric parameters with equal distribution before and after research (p>0,05 for all measurements).