Different Faces of Sinonasal Mass Lesions (original) (raw)
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Histopathological Patterns of Sinonasal Masses: A Hospital-Based Study
Journal of Evolution of Medical and Dental Sciences, 2016
BACKGROUND Sinonasal masses are one of the commonest cause of nasal obstruction with or without nasal discharge. Sinonasal masses may show diverse histopathological patterns. The sinonasal masses may be non-neoplastic lesions like nasal polyps either inflammatory or allergic type, traumatic lesions, granulomatous lesions or neoplastic lesions. Neoplasms of sinonasal masses form a wide spectrum like angiofibroma, capillary haemangioma at one end while squamous cell carcinoma at the other end of the spectrum. Benign neoplastic lesions arising from nasal cavities, paranasal sinuses and nasopharynx may threaten the patients because of their high recurrence rate and propensity for malignant potential. Any masses, which are seen in the area of nasal cavities and paranasal sinuses are termed as "sinonasal masses." Histopathological examination is the only means of determining the nature and patterns of these sinonasal masses, i.e. non-neoplastic versus neoplastic. AIMS AND OBJECTIVES A hospital-based study to determine the histopathological patterns of sinonasal masses. MATERIALS AND METHODS The present study was based on histopathological analysis of 120 specimens of sinonasal masses presented at Pathology
The Utility of Clinicopathological Correlation of Sinonasal Masses in a Tertiary Hospital
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Sinonasal masses are commonly seen lesions in ENT practice with multiple aetiological factors. We wanted to study the clinico-pathological features of nasal mass specimens in a tertiary hospital and evaluate the utility of routine histopathological examination of the surgically removed nasal tissue specimens. METHODS All the histologically examined specimens of patients clinically presenting with nasal or sinonasal lesions over a period of one year were retrospectively studied and analyzed. RESULTS Out of total 36 patients with masses, 21 were males (58.3 %) and 15 (41.7 %) were females. The age ranged from 10 to 75 years with a mean age of 31.4 years and maximum patients were in the third decade (37.5 %). The most common presenting clinical symptom was nasal obstruction that was seen in 33 patients (91.6 %). Computed tomography (CT) scan was done in 94.5 % of cases prior to the surgical intervention. One fifth of the sinonasal lesions were neoplastic as per histopatholog...
CLINIC-PATHOLOGICAL PROFILE OF SINONASAL MASSES
A wide majority of lesions in the nose and the paranasal sinuses present as polypoidal mass in the nasal cavity. The Inflammatory conditions, infections, chronic rhino sinusitis, benign lesions and even malignancies can also present as nasal polyps. Early stage of malignancies in the nose is often misdiagnosed inadvertently. This is because malignancies too present as mass in the nose that mimics benign lesions and often associated with chronic rhino sinusitis. The present study was undertaken to know the clinic-pathological profile of sinonasal masses. The study group included 102 patients with nasal polypoidal masses, all patients were subjected to detailed history and clinical examination. All necessary investigations were done at greater accuracy. The final diagnosis was made after the histopathological examination of the excised masses. Depending on the final diagnosis, all masses were divided into non-neoplastic and neoplastic groups. Total 102 patients who presented with nasal polypoidal masses, of which 89 turned out to be non-neoplastic lesions and 13 were neoplastic, study showed that non-neoplastic lesions are very more common than neoplastic lesions. The Male patients were more prone to the formation of lesions when compared with non-neoplastic lesions. The nasal polyps were formed eighty-one percent. The study can found that, there is a high chance of discrepancy between the clinical and histopathological diagnosis.
2016
Introduction: Neoplasms of the sinuses and nasal cavity account for 0.2–0.8 % of all carcinomas. The present study was carried out to find out correlation of clinical, radiological and histopathological diagnosis of sinonasal masses. Material and Methods: The present study was carried out on 60 patients of any age and sex randomly selected who presented with sinonasal masses in the department of Otorhinolaryngology and Pathology in Guru Gobind Singh Medical College and Hospital, Faridkot. These cases were subjected to routine hematological and biochemical evaluation, nasal endoscopy, xray paranasal sinuses/ CT scan and biopsy. Tissues were routinely processed for histopathological sections of 5 micron thickness and were stained by hematoxylin and eosin stain. Special staining by reticulin, von gieson, PAS and masson’strichrome were undertaken whenever applicable. The data so obtained was compiled, analyzed and valid conclusion drawn. Results: In present study, histopathology showed ...
Uncommon and Atypical Sinonasal Masses: Diagnostic and Therapeutic Challenges
An International Journal Clinical Rhinology, 2012
Introduction Sinonasal masses are a wide range of pathologies ranging from simple nasal polyps to rare tumors like esthesioneuroblastomas. Early symptoms of all of them are similar to common nasal and sinus problems, hence, producing a delay in diagnosis. Materials and methods All the patients presenting with sinonasal masses in the Department of ENT and Head/Neck Surgery, SRMS Institute of Medical Sciences, Bareilly, were included in the study. The study was carried out between January 2007 and December 2011. Detailed history and ENT examination were recorded. Radiological investigation was carried out in the form of computed tomographic (CT) scan of nose and paranasal sinuses. Final diagnosis was made by histopathological examination either before instituting any form of treatment or by a postsurgical biopsy where surgery was carried out. Immunohistochemistry was done in some cases as deemed necessary by the pathologist. Thus, their modes of presentation, radiological and histopat...
International Journal of Otorhinolaryngology and Head and Neck Surgery
Background: Purpose of study was to evaluate clinical, radiological, pathological correlation of sinonasal masses, to correlate age and sex with etiology of sinonasal masses and to evaluate percentage of patient having malignancy.Methods: This was a hospital based prospective observational study. In this study total numbers of 69 cases of sinonasal mass were selected from those patients who were admitted in department of otorhinolaryngology and head and neck surgery SAMC and PGI Indore MP from June 2019 to August 2021.Results: Sinonasal masses are more common in 4th to 6th decade, males, farmers and lower socioeconomic status. Most common presented symptom with sinonasal mass was nasal obstruction. Patients shows polypoidal mass in nasal endoscopy, which was most common finding. Most of the patients radiological scan shows the opacity. 26.1% cases were neoplastic and rest non neoplastic. These rules however, may be broken in sinonasal imaging. The relative number of non-neoplastic a...
Journal of Evolution of Medical and Dental Sciences, 2016
BACKGROUND Mass in the nasal cavity is frequently encountered in routine ENT practice. The histopathological profiles of these masses are diverse and diagnosis can often be challenging for the clinician and the pathologist. MATERIALS AND METHODS A one-year observational study was conducted in a tertiary care centre to study the clinicopathological profile of sinonasal mass. RESULTS A total of 34 cases were included in the study which included 22 males and 12 females. The most common presenting complaints were nasal obstruction (88.2%) followed by epistaxis (44.1%). Though majority of the patients presented within six months of onset of symptoms, about 35.3% of the patients presented within six to twelve months of the onset of symptoms. Sinonasal polyps (47.1%) were the most common histological diagnosis while squamous cell carcinoma of the maxilla was the most common malignancy (17.6%), followed by sinonasal lymphoma and melanoma (5.9% each) and olfactory neuroblastoma (2.9%). 73% of the lesions were amenable to surgical treatment. CONCLUSION The treatment of sinonasal lesions depend on the histological profile and the diagnosis of the same can often be a challenging task. One has to be aware of the differential diagnosis and rule them out by proper histological evaluation.
Clinico-pathological spectrum of sinonasal masses: a tertiary care hospital experience
International Journal of Otorhinolaryngology and Head and Neck Surgery
INTRODUCTION Sinonasal masses (SNM) are a fairly common clinical entity that occurs amongst patients of all age groups and are encountered routinely in ENT outpatient departments. They encompass a very wide range of pathologies ranging from non-neoplastic to neoplastic in nature. 1 Their presenting features are diverse and depend upon the type, spread and extent of the primary disease. Accordingly, the patients may have nasal features (obstruction, discharge, nasal mass, epistaxis, smell abnormalities), features of oro-facial involvement (palatal or buccal swelling, loose teeth, facial pain and swelling), orbital features (epiphora, proptosis, diplopia), aural features (fullness, hearing impairement), and/or metastatic neck nodes. 2 These masses can be congenital or acquired. Congenital masses such as dermoid cysts, glioma and encephaloceles are predominantly midline swellings, and may present either intranasally or extranasally. 3,4 Acquired sinonasal masses can be inflammatory including allergic, traumatic, granulomatous or neoplastic (benign and malignant) in nature. 5 Aquired pathologies presenting with sinonasal ABSTRACT Background: Sinonasal masses (SNM) are a fairly common clinical entity that occurs amongst patients of all age groups. There symptoms and signs frequently overlap, hence a diagnostic dilemma exists. A correct diagnosis is prudent for instituting correct treatment and expecting recovery. The purpose of this retrospective analysis was to decipher and study the various pathologies that present as sinonasal masses. Methods: A retrospective analysis done on 80 patients of SNM who presented to the Department of ENT, Subharti Medical College and Hospital, Meerut from May 2016 to April 2017. Their biodata, clinical profile and histolopathological diagnosis were analyzed. Results: SNM were male predominant and were non-neoplastic in 53 cases (66.25%). Nasal obstruction was the most common presenting feature (71 cases, 88.75%). Nasal polyps are the most commonly encountered SNM. Nonneoplastic SNM were common in the age group of 11 to 40 years. Benign SNM were common during the 2 nd to 4 th decade of life, while malignant SNM were common from 5 th decade onwards. Conclusions: SNM constitute a very wide spectrum of differential diagnoses. They have a male predominance and majority are non-neoplastic. Nasal polyps are the most commonly encountered SNM, seen during 2 nd to 4 th decade of life, while squamous cell carcinoma is the most commonly encounterd malignancy, generally from 5 th decade onwards. Surgery is the treatment of choice.
Clinico-pathological and radiological assessment of benign nasal masses
International Journal of Otorhinolaryngology and Head and Neck Surgery
A variety of neoplastic, non-neoplastic and inflammatory conditions involve the sinonasal cavity and these are encountered in day to day clinical practice. Incidence of these lesions is often stated to be between 1% and 4% of the population. 1 Sinonasal masses can be divided into two main categories: non neoplastic and neoplastic, which in turn are further divided into benign and malignant. Benign neoplasia of the nose and paranasal sinuses is relatively not uncommon. The benign nasal masses include nasal polypi, inverted papillomas, osteomas, haemangiomas, angiofibromas, meningocoel and meningoencephalocoele. The prevalence rate of nasal polyposis is about 2%. 2 Antrochoanal polyp is the most common choanal polyp arising from one of the paranasal sinuses. 3 Various pathologal events ranging from nonneoplastic to malignant sinonasal tumors may mimic a simple mass. Common causes of nasal obstruction are inflammatory polyps, with a prevalence of 4% in general population. 4 Benign tumors are relatively common, but malignant neoplasms are rare, relaying to 0.2-0.8% of all ABSTRACT Background: Sinonasal masses are uni or bilateral with variable and with multiple etiological factors. Benign masses are common in comparison to malignant in this region. Some of the benign masses e.g. juvenile angiofibroma and inverted papilloma cause local bony destruction. Preoperative radiological assessment is desirable for proper surgical Management. The purpose of the study was to assess the clinical and radiological findings of sinonasal masses and the correlation of the clinical and radiological findings with the histopathology. Methods: This prospective study was carried out on 50 cases if intra nasal masses. After clinical examination, these patients were subjected to radiology. The parameters assessed were the origin, extension, involvement of adjacent structure. Subsequently, all the cases were subjected to surgery i.e. polypectomy, medial maxillectomy, excision with the help of nasal endoscope. Thereafter, the histopathological findings were correlated with clinical and radiological findings. Results: Total 50 cases of intra nasal benign masses were included in the study. Among them 36 (72%) cases were of nasal polyps, out of which 29 (80.5%) were inflammatory polyps and 7 (19.4%) were allergic polyps. Among inflammatory polyps, 23 (79.3%) were males and 6 (20.69%) were females. Among allergic polyps 4 (57.14%) were males and 3 (42.85%) were females. The other findings were 5 (10%) cases of angiofibroma, 5 (10%) cases on inverted papilloma, 3 (6%) cases of haemangioma and 1 (2%) cases of chondrosarcoma. Conclusions: Considering the result obtained, the most common sinonasal lesions were inflammatory polyps. Others in order in order of frequency were allergic polyp, angiofibroma, inverted papilloma, haemangioma and chondrosarcoma.
Benign Sinonasal Masses: A Clinicopathological and Radiological Profile
Kathmandu University Medical Journal, 2014
Background Benign nasal and paranasal sinus masses are commonly encountered in clinical practice. Though benign, certain nasal polyps, fungal sinusitis, hemangiomas and fibro-osseous tumors can present with locally destructive features and deformities, mimicking malignancies at once. Objective This study was carried out to recognize the great variety of benign nasal lesions and their frequency in our region. Methods A retrospective chart analysis of cases presenting as mass in nose and paranasal sinus that underwent surgery over three years duration at our institute was done. A provisional diagnosis was made after clinical assessment and radiological investigations, but the final diagnosis was established after histopathological examination. Results A total 331 cases presented as masses in nose and paranasal sinus presented during the period. The clinicopathological examination aided by endoscopic and imaging studies revealed the non neoplastic benign masses in 293 and neoplastic ma...