Lipomannan and Lipoarabinomannan from a Clinical Isolate of Mycobacterium kansasii: NOVEL STRUCTURAL FEATURES AND APOPTOSIS-INDUCING PROPERTIES (original) (raw)

This study investigates the lipomannan (LM) and lipoarabinomannan (LAM) extracted from a clinical isolate of Mycobacterium kansasii, focusing on their structural characteristics and biological effects. LAM and LM structures were thoroughly analyzed, revealing novel features that differ from other mycobacterial species. Additionally, the study assesses the impact of these structures on apoptosis in human macrophages, contributing to a clearer understanding of the virulence mechanisms of M. kansasii and its implications in pathogenicity and disease progression.