The correlation between colposcopy, cervical cytology and histopathology in the diagnosis and management of cervical lesions: a cross sectional study (original) (raw)
Related papers
Comparative evaluation of colposcopy, cytology and histopathology for diagnosis of cervical lesions
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2019
Background: Cervical cancer is the fourth most frequent cancer globally in women with an estimated 570,000 new cases and 311,000 deaths in 2018 representing 6.6% of all female cancers. To correlate the cytology, colposcopy and histopathology of cervical lesions in patients attending gynaecology OPD in a tertiary care centre, Ghaziabad.Methods: 208 women were enrolled from Gynaecology OPD of Santosh Medical College and Hospital, Ghaziabad, irrespective of their chief complaints. Women aged 19-80 years were included in the study group. Those with pregnancy and already diagnosed or treated with CIN, Cervical cancer or Cervical HPV infection were excluded from the study. PAP-smear was taken for all the patients followed by colposcopy without waiting for PAP-smear report. Cervical biopsy was taken from patients with abnormal colposcopic findings (90 patients).Results: Majority of women were in age group 30-39 years. 37.5% had unhealthy, 21.6% had hypertrophied cervix and only 9.1% had no...
THE PROFESSIONAL MEDICAL JOURNAL, 2016
The aim of our study is to compare the efficacies of Pap smear cytology, colposcopy and histopathology, in diagnosis of cervical diseases. Study Design: Cross sectional cohort study. Period: One year from June 2013 to June 2014. Setting: Tertiary care hospital in Karachi, Pakistan. Method: The patient population n=145 consisted of women ranging from age 18 to 80 years old, who had come to the outpatient clinics for a variety of symptoms. Pap smear, colposcopy and histopathology was done for women who had symptoms like recurrent vaginal discharge, postcoital bleeding and other diseases of the cervix. Findings were noted on a proforma and all the patients signed a duly informed consent. Data was analyzed using SPSS version 23. Results: The mean age was 45 +/-9 years (between 24-75 years), the parity was 5 +/-4, normal colposcopy findings were found in n= 66 women, while abnormal findings were found in n=79 women. In the abnormal colposcopic finding group n=63 had abnormal histopathology (p<0.001) abnormal histopathology was found in n=11 women who had normal colposcopic findings (16.67% false negative), the calculated sensitivity and specificity of colposcopy was determined to be 86% and 79%. For pap smear abnormality was found in n= 49 patients, out of which n=29 had abnormal findings on histopathology as well. And for colposcopy and pap smear out of n= 78 patients who had abnormal colposcopic findings, abnormal pap smear was found in only n= 28 patients. And out of those who had normal colposcopy n= 67, n= 21 had abnormal pap smear (False positivity of 31.34%) similarly out of those who had normal pap smear n= 96, n= 44 had abnormal histopathology (false negativity of 45.83%). The calculated sensitivity and specificity of pap smear was 38.8% and 71.8% respectively. Conclusion: We have concluded that there is a strong correlation between findings of colposcopy and histopathological diagnosis, but when it comes to the diagnosis made by pap smear and colposcopy and pap smear and histopathology the correlation is weak and not consistent.
International journal of health sciences
Introduction–Colposcopy is the diagnostic method for cervical cancer. It involves visualization and examination of cervix, vagina and vulva with the aid of a colposcope. Similar to pap smear, colposcopy is also a non-invasive method but is expensive and thus it is used as typically to assess the presence, location, size, extent, as well as type of pre-cancer or cancer. Also, it is helpful in guiding the appropriate site for taking the biopsy for histopathological examination.Objective- To study the colposcopic findings of cervical lesions in patients and to differentiate between benign and malignant cervical lesions. Also, correlating the colposcopic findings with histopathological findings. Material and methods- The present study entitled “Study of Colposcopic and Histopathological Correlation for Cervical Lesions at Tertiary Care Centre” was conducted in Department of Obstetrics and Gynecology on a total of 250 females. Data was compiled and correlation between the findings of co...
Journal of Dhaka Medical College, 2013
Objective: To correlate Paps smear and colposcopic finding of cervix with histopathological report of abnormal area of cervix in a group of patient attending a tertiary hospital. Methods: It was a cross-sectional prospective study done in one year period from January to December 2007 in Colposcopy Clinic of Institute of Child and Maternal Health (ICMH) Hospital, Dhaka. The study carried out including fifty two female patients having clinically unhealthy cervices as in the form of hypertrophy, erosion, congestion or bleeds on touch or having positive pap smear found during P/V or P/S examination, attending gynaecology out patient department of ICMH Hospital after fulfilling all the inclusion criteria. Result: The present study showed a correlation between cervical cytology and colposcopically directed biopsy, the correlation was accurate within one grade in 39 of 51 cases (76.16%) (as cytology was not done in one case). Other studies showed cytologic accuracy (within one level of hi...
Colposcopic evaluation of cervical lesions: a prospective study
International Journal of Clinical Trials, 2014
cervix occupies the top rank or second among cancers in women in developing countries. So that, there is an urgent need for initiation of community screening and educational programs within the source for the control and prevention of cervical cancer in India. 4 Papanicolaou (Pap) smears are used to screen for cervical cancer, here the "screening for cancer" means looking for cancer before a person has symptoms. There are no organized screening programs in any province or region of India. Screening of asymptomatic women is practically absent, even among otherwise well-organized health care programs of the industrial and military sectors. 5 Resource constraint has been a major hurdle in organizing screening programs. It has been estimated that in India, even with
Role of Colposcopy in the Evaluation of Unhealthy Cervix and Cervical Intraepithelial Neoplasia
Journal of Evidence Based Medicine and Healthcare, 2020
BACKGROUND Invasive cancer of cervix is preventable because it has a long pre-invasive phase, cervical cytology screening is possible, and the treatment of pre-invasive lesions is effective. There are various methods available for screening of cervical precancerous and cancerous lesions like Visual Inspection by Acetic Acid (VIA), Visual inspection by Lugol's Iodine (VILI), conventional pap smear, liquid based cytology, colposcopy and HPV DNA testing. But, negative cytology does not rule out cervical intraepithelial lesions (CIN) completely. In this study we have studied patients with symptoms, abnormal appearing cervix, and patients with abnormal cytology by colposcopy to detect intraepithelial neoplasia of cervix. METHODS In this cross-sectional observational study of 149 subjects, women attending outpatient department of Obstetrics and Gynaecology who were symptomatic for recurrent and persistent vaginal discharge, postcoital bleeding, menstrual abnormalities were examined by per speculum examination and cervical cytology obtained. In indicated patients, colposcopy was done and colposcopic directed biopsy of lesions was taken for evaluation and the results compared. RESULTS Colposcopy showed accurate estimation in 57.89% cases, over estimation in 36.84% cases and under estimation in 5.26% cases. Sensitivity of colposcopy in our study was 98.30%. Specificity of colposcopy in present study was 57.30%. Positive predictive value of colposcopy in our study was found to be 68.75%, negative colposcopy value was 96.66%. Prevalence of CIN in our study group was found to be 39.43%. CONCLUSIONS Colposcopy was found to be useful in understanding the morphology of the cervical lesions, both of the benign and neoplastic and this was very helpful in planning their management. In spite of less specificity and less positive predictive value in our study, a detailed colposcopic evaluation of cervix with a guided biopsy is recommended as an important diagnostic method for the detection of precancerous lesions and early cervical cancer.
Correlation of colposcopic findings with biopsy in cervical cancer screening
International Journal of Clinical Obstetrics and Gynaecology, 2020
Aim: to correlate the colposcopic findings with biopsy in cases of abnormal cervical cytology Materials and Methods: This was a prospective clinical study conducted among 300 women who fulfilled the selection criteria were conducted in the Department of Obstetrics and Gynaecology at Muzaffarnagar Medical College & Mahesh hospital from the November 2017 to November 2019. Patients who had pathological cervical appearance or Pap smear results of ASCUS, AGUS, LSIL or HSIL were referred to colposcopy. Results: Majority (40.0%) women were between 30-39 years of age group. Histopathology confirmed chronic cervicitis in 5 (9.1%) cases, 35 (63.6%) women with CIN I, 12 (21.8%) with CIN II, 3 (5.5%) with CIN III. The colposcopy and histopathology findings correlated in 90.9% cases. Conclusion: study demonstrated correlation between colposcopy and histology. Women with clinical diagnosis of unhealthy cervix should be evaluated by cytology to detect any premalignant or malignant lesions.
2013
Objectives: To determine the correlation between cytology, colposcopy and histopathology, individually and in combination, in high-risk patients for detection of early cancer of the cervix. Materials and methods: A total of 200 high-risk patients in the age groups of 35 to 60 years were included in the study. Pap smear, colposcopy and colposcopically directed biopsies were taken from the suspicious area. Results: Sensitivity, specificity and positive predictive value of Pap smear are 65.2, 96.3 and 89.3% respectively. Correlation between cytology and colposcopy was 81%, between colposcopy and histopathology was 90.6%, between cytology, colposcopy and histopathology was 90.6% and between cytology, colposcopy and histopathology was 87.3%. Conclusion: Combination of various methods increases the diagnostic accuracy over that of each method separately.
2015
The objective was to assess the correlation of pap smear and colposcopy in relation to histopathological findings in detection of premalignant lesions of cervix. A total of 200 women with lesions of cervix were recruited for the study. Pap smear and colposcopy was performed in all the patients. Final correlation of pap smear and colposcopy were based on histopathology. Majority of patients in our study presented with complains of white discharge 119 (59.5%) out of 200 women. Followed by complains of post coital bleeding (15.5%), irregular menstrual cycles (10.5%) and intermenstrual bleeding(10.5%). In our study sensitivity of pap smear was lower(50%) than colposcopy which had high sensitivity(96.42%) and specificity of pap smear was higher (86.62%) than colposcopy (39.53%) respectively. Pap smear, colposcopy and directed cervical biopsy together are useful and complementary in arriving at a correct diagnosis. Benign cervical erosions respond well to local/ systemic antibiotics. Prem...