Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now? (original) (raw)

This paper discusses the advancements and challenges in the field of cytokine gene transfer for tumor inhibition and therapy. It highlights the engineering of tumor cells to produce cytokines, termed as Tumor Cytokine Cells (TCCs), which can potentially induce systemic immunity against tumors. The review emphasizes the necessity for a deeper understanding of the immune mechanisms involved, the importance of standardizing experiment data presentation, and the future directions for enhancing the effectiveness of this therapeutic approach.