Evaluation of the Efficacy of Saccharomyces cerevisiae Cell Wall to Ameliorate the Toxic Effects of Aflatoxin in Broilers (original) (raw)

2003, International Journal of Poultry Science

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Effects of Yeast Glucomannan and Sodium Bentonite on the Toxicity of Aflatoxin in Broilers

Revista Brasileira de Ciência Avícola, 2015

The aim of this study was to evaluate the efficacy of a yeast glucomannan (YG) and sodium bentonite (SB) in reducing the toxicity of aflatoxin for broilers fed a diet naturally contaminated with aflatoxin. In total, 300 7-day-old Ross 308 broilers were randomly assigned to 10 dietary treatments, consisting of a diet with no aflatoxin (positive control), a diet naturally contaminated with 250 ppb aflatoxin (negative control), and eight aflatoxin-contaminated diets supplemented with different SB and YG and their combinations. Serum biochemical parameters and liver pathological changes were investigated when broilers were 42 days old. The birds fed the negative control diet presented lower uric acid, cholesterol, and triglyceride levels and higher in AST and ALT activities compared with the positive control group. In addition, negative-control birds also showed significant histopathological changes (p<0.05), including slight to moderate hydropic degeneration and/or fatty changes (8 cases), bile-duct hyperplasia (7 cases), periportal fibrosis (5 cases), cells infiltration (4 cases), congestion (3 cases) as well gross pathological changes. The addition of YG and SB to the aflatoxin-contaminated diet partially alleviated the negative effects of aflatoxin. However, the supplementation 0.1% YG alone to the aflatoxin-contaminated diet significantly prevented the adverse effects of aflatoxin on serum biochemical parameters and pathological liver changes and was found to be more effective than other treatments.

Low Level of Aflatoxin in Broiler at Experimental Conditions. Use of Cell Wall Yeast as Adsorbent of Aflatoxin

Archives of Veterinary Science, 2003

Este estudo foi realizado para avaliar a eficácia da parede celular de Saccharomyces cerevisiae (PCSC) como inibidor dos efeitos tóxicos da aflatoxina em frangos de corte de 1 a 42 dias de idade. Foram utilizados 320 frangos distribuídos em quatro tratamentos com quatro repetições de 20 aves cada: T1- controle; T2 – 0.1% PCSC; T3 – 500 ppb de aflatoxina; T4 – 0.1% PCSC + 500 ppb de aflatoxina. Os parâmetros avaliados foram consumo de ração; ganho de peso; conversão alimentar; peso relativo de fígado, rins e bursa de Fabricius. O nível de Aflatoxina da dieta afetou (P0,05) outros parâmetros de desempenho aos 21 e 42 dias de idade. A PCSC melhorou a conversão alimentar das aves expostas ou não à aflatoxina aos 42 dias de idade. A aflatoxina e/ou PCSC da dieta não afetaram o peso relativo dos órgãos avaliados. Não foram observadas interações entre aflatoxina e PCSC. Os resultados demonstram que, nos níveis utilizados no presente estudo, a aflatoxina não causa efeitos deletérios às aves...

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