The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels (original) (raw)
Biological Evidence That SOCS-2 Can Act Either as an Enhancer or Suppressor of Growth Hormone Signaling
Nicos Nicola
Journal of Biological Chemistry, 2002
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SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine
Sandra Nicholson
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SOCS2 negatively regulates growth hormone action in vitro and in vivo
Ian Street, Nicos Nicola
Journal of Clinical Investigation, 2005
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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation
David De Souza
Molecular and cellular biology, 2002
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Ubiquitin System-Dependent Regulation of Growth Hormone Receptor Signal Transduction and Effects of Oxidative Stress
Julia Schantl
From Classical Biochemistry to Human Diseases, 2002
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A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation
Andrew Brooks
Oncogene, 2017
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Growth Hormone Preferentially Induces the Rapid, Transient Expression of SOCS-3, a Novel Inhibitor of Cytokine Receptor Signaling
Nils Billestrup
Journal of Biological Chemistry, 1998
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17β-Estradiol positively modulates growth hormone signaling through the reduction of SOCS2 negative feedback in human osteoblasts
Gianfranco Fraschini, Isabella Villa
Bone, 2013
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The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins
Kazuhiro Iwai
FEBS Letters, 2006
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Growth Hormone Regulation of SOCS-2, SOCS-3, and CIS Messenger Ribonucleic Acid Expression in the Rat*
amilcar morales
Endocrinology, 1999
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Running head: SOCS upregulation participates in stem cell mobilization
Antonio Bernad
2006
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Mechanism of Inhibition of Growth Hormone Receptor Signaling by Suppressor of Cytokine Signaling Proteins
Nils Billestrup
Molecular Endocrinology, 1999
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Growth Hormone Receptor Regulation in Cancer and Chronic Diseases
Julia Schantl
Frontiers in Endocrinology
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Growth hormone regulates the expression of UCP2 in myocytes
Tetsuya Tagami
Growth Hormone & IGF Research, 2016
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GH directly stimulates UCP3 expression
Tetsuya Tagami
Growth Hormone & IGF Research, 2018
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Expression of SOCS1, SOCS2, and SOCS3 in growth hormone-stimulated skin fibroblasts from children with idiopathic short stature
Fernanda Morales
Journal of Pediatric Endocrinology and Metabolism, 2012
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SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer
G. Norstedt, Guido Jenster, Pernilla Wikström
Carcinogenesis, 2014
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Impaired JAK-STAT signal transduction contributes to growth hormone resistance in chronic uremia
Pouneh Nouri, Ralph Rabkin
Journal of Clinical Investigation, 2001
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Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase
Christina Aaen, Stine Smedegaard
Journal of Biological Chemistry, 2014
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Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptor
Ida Chen
Biochemical Journal, 2003
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Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions
amilcar morales
Cytokine & Growth Factor Reviews, 2006
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Lack of Socs2 Expression Causes the High-Growth Phenotype in Mice
Juan F Medrano
Genomics, 2001
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Mutation of the SHP-2 Binding Site in Growth Hormone (GH) Receptor Prolongs GH-Promoted Tyrosyl Phosphorylation of GH Receptor, JAK2, and STAT5B
Nils Billestrup
Molecular Endocrinology, 2000
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The SOCS Box of SOCS-1 Accelerates Ubiquitin-dependent Proteolysis of TEL-JAK2
Toshio Kitamura
Journal of Biological Chemistry, 2001
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Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis
gent gent
Proceedings of The National Academy of Sciences, 2002
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