The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress (original) (raw)

REVIEW OF NRF2-REGULATED GENES INDUCED IN RESPONSE TO ANTIOXIDANTS

editor ijmrhs

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The Nrf2Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

Ha Nguyen

Journal of Biological Chemistry, 2009

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Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases

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Free Radical Research, 2010

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Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues and energy status, and pathways through which it attenuates degenerative disease

Albena Dinkova-kostova

Free radical biology & medicine, 2015

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Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

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Molecular Aspects of Medicine, 2011

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The Nrf2-Keap1 Signalling Pathway: Mechanisms of ARE transcription regulation in antioxidant cellular defence

azman Abdullah

International Journal of PharmTech Research

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Translational control of nrf2 protein in activation of antioxidant response by oxidants

Lena Shevelev

2007

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Nrf2 as a modulator of oxidative stress

Yassir Al-Mulla Hummadi

Al-ʻulūm al-ṣaydalāniyyaẗ, 2022

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Review Nrf2: A MASTER REGULATOR OF CELLULAR DEFENSE MECHANISM AND A NOVEL THERAPEUTIC FACTOR

Ghulam Zahra Jahangir

2017

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Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels

Takafumi Suzuki

Molecular and Cellular Biology, 2013

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Nrf2–ARE signaling in cellular protection: Mechanism of action and the regulatory mechanisms

ansuman chatterjee

Journal of Cellular Physiology, 2019

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Redox activation of Nrf2 & NF-κB: A double end sword?

Mabel Buelna

Cellular Signalling, 2013

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L 11 . 2 Role of Nrf 2 transcription factor in regulation of cellular response against oxidative stress

Claudine Kieda

2008

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Introduction to Special Issue on “Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases”

Albena Dinkova-kostova

Free Radical Biology and Medicine, 2023

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Nrf2-Keap1 Activation, A Promising Strategy in the Prevention of Cancer

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Free Radicals and Antioxidants, 2016

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Molecular basis of the Keap1-Nrf2 system

Takafumi Suzuki

Free radical biology & medicine, 2015

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Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered

Vỹ Ngô

International Journal of Molecular Sciences, 2021

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Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-κB

Alvin Chia

Biochemical Pharmacology, 2010

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Nrf2, the Master Regulator of Anti-Oxidative Responses

Andreas Von Knethen

International Journal of Molecular Sciences

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Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

Tin Khor

Biochemical Pharmacology, 2008

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Nrf2 Amplifies Oxidative Stress via Induction of Klf9

Katerina Leonova

Molecular Cell, 2014

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Modulation of Nrf2/Keap1 pathway by dietary phytochemicals

Ahmed Salah Atia

International Journal of Research in Medical Sciences, 2014

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Toward clinical application of the Keap1–Nrf2 pathway

Takafumi Suzuki

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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

Tommy Johansen

Journal of Biological Chemistry, 2010

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Nrf2 transcriptional derepression from Keap1 by dietary polyphenols

K. Srai

Biochemical and Biophysical Research Communications, 2016

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Emerging Role of Nrf2 in Protecting Against Hepatic and Gastrointestinal Disease

Jose Manautou

Toxicologic Pathology, 2007

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Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

Tetsuro Ishii

Journal of Biological Chemistry, 2000

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Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

Takafumi Suzuki, Akira Kobayashi

… and cellular biology, 2008

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A systems biology perspective on Nrf2-mediated antioxidant response

Courtney Woods

Toxicology and applied pharmacology, 2010

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Role of G12 and G13 as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor†

Sangdun Choi

Mol Cell Biol, 2007

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