Negative feed-forward control of TNF by tristetraprolin (ZFP36) is limited by the mitogen-activated protein kinase phosphatase, DUSP1: implications for regulation by glucocorticoids (original ) (raw )Glucocorticoids Regulate Tristetraprolin Synthesis and Posttranscriptionally Regulate Tumor Necrosis Factor Alpha Inflammatory Signaling
John Cidlowski
Molecular and Cellular Biology, 2006
View PDFchevron_right
Association Between IL-1 β /TNF- α –Induced Glucocorticoid-Sensitive Changes in Multiple Gene Expression and Altered Responsiveness in Airway Smooth Muscle
Hakon Hakonarson
American Journal of Respiratory Cell and Molecular Biology, 2001
View PDFchevron_right
Role of RNA-binding protein tristetraprolin in tumor necrosis factor-α mediated gene expression
Cristiana Stellato
Biochemical and Biophysical Research Communications, 2012
View PDFchevron_right
DUSP1 maintains IRF1 and leads to increased expression of IRF1-dependent genes: A mechanism promoting glucocorticoid-insensitivity
Mahmoud Mostafa
The Journal of biological chemistry, 2016
View PDFchevron_right
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
J. Grooten
Mucosal Immunology, 2015
View PDFchevron_right
Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability
Matthew Brook
Molecular and Cellular Biology, 2001
View PDFchevron_right
Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation
Ivo L Hofacker
Molecular systems biology, 2011
View PDFchevron_right
Restoration of Corticosteroid Sensitivity by p38 Mitogen Activated Protein Kinase Inhibition in Peripheral Blood Mononuclear Cells from Severe Asthma
Amir Hakim
PLoS ONE, 2012
View PDFchevron_right
Allergic Lung Inflammation Required for the Development of Expressed in Resident Lung Cells Is TNF Receptor-Associated Factor 1
Hans Oettgen
2000
View PDFchevron_right
Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: Possible partners in the combat against inflammation
Ilse Beck
Biochemical Pharmacology, 2009
View PDFchevron_right
Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
Magali Mouy
Proceedings of the National Academy of Sciences of the United States of America, 2005
View PDFchevron_right
IL-1β Augments TNF-α–Mediated Inflammatory Responses from Lung Epithelial Cells
Gloria Pryhuber
Journal of Interferon & Cytokine Research, 2009
View PDFchevron_right
Role of transcription factors in inflammatory lung diseases
Ifty rahman
1998
View PDFchevron_right
Corticosteroid Inhibition of Growth-Related Oncogene Protein- via Mitogen-Activated Kinase Phosphatase-1 in Airway Smooth Muscle Cells
Kian Chung
The Journal of Immunology, 2007
View PDFchevron_right
Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients
Brian O'Connor , Chris Corrigan
Journal of Allergy and Clinical Immunology, 2006
View PDFchevron_right
Cytokines Alter Glucocorticoid Receptor Phosphorylation in Airway Cells
Omar Tliba
American Journal of Respiratory Cell and Molecular Biology, 2012
View PDFchevron_right
Long-acting β2-agonists promote glucocorticoid-mediated repression of NF-κB by enhancing expression of the feedback regulator, TNFAIP3
Mahmoud Mostafa
American journal of physiology. Lung cellular and molecular physiology, 2016
View PDFchevron_right
Transcriptional Regulation of Inflammatory Genes Associated with Severe Asthma
Rachel Hall-Clifford
Current Pharmaceutical Design, 2011
View PDFchevron_right
Post-transcriptional regulation of pro-inflammatory gene expression
Danièle Noël
Arthritis research, 2000
View PDFchevron_right
Molecular basis of chronic inflammation in lung diseases: new therapeutic approach
Jan Braszko , Robert Mroz
Journal of physiology and pharmacology: an official journal of the Polish Physiological Society
View PDFchevron_right
Impaired Dual-Specificity Protein Phosphatase DUSP4 Reduces Corticosteroid Sensitivity
Kazuhiro Ito
Molecular pharmacology, 2017
View PDFchevron_right
TNF-α as a promising therapeutic target in chronic asthma: a lesson from rheumatoid arthritis
Cristina Russo
Clinical Science, 2005
View PDFchevron_right
Persistent Activation of Nuclear Factor–κB Signaling Pathway in Severe Uncontrolled Asthma
Giovanni Bonsignore
American Journal of Respiratory and Critical Care Medicine, 2003
View PDFchevron_right
The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself
Matthew Brook
Journal of Biological Chemistry, 2004
View PDFchevron_right
p38 Mitogen-activated protein kinase–induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
Kian Chung
Journal of Allergy and Clinical Immunology, 2002
View PDFchevron_right
Defects of Protein Phosphatase 2A Causes Corticosteroid Insensitivity in Severe Asthma
Kazuhiro Ito
PLoS ONE, 2011
View PDFchevron_right
Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation
achille patrizio caputi
The Journal of Immunology, 2006
View PDFchevron_right
Essential role of NF-κB and AP-1 transcription factors in TNF-α-induced TSLP expression in human airway smooth muscle cells
Naresh Singh Redhu
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2010
View PDFchevron_right
Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10
Valeria Poli
The Journal of Immunology, 2009
View PDFchevron_right