PROSPECTIVE STUDY OF CANNABIS WITHDRAWAL IN CANNABIS-USING ADOLESCENTS (original) (raw)
2008, Journal of The American Academy of Child and Adolescent Psychiatry
Milin and colleagues are to be commended for conducting "the first published prospective study of cannabis withdrawal in adolescents with cannabis dependence seeking treatment that is not confounded by other co-morbid substance use disorders" 1 (p. 178) . The authors tested two hypotheses: 1) "a withdrawal syndrome with clinically significant and measureable symptoms will follow abrupt cessation of cannabis use;" and 2) "the intensity of the withdrawal syndrome will be dependent on the quantity of cannabis used, frequency of exposure, length of cannabis dependence, and/or age at onset of daily cannabis dependence and mental health status" 1 (p 175) . Results showed that adolescents seeking treatment for cannabis dependence exhibit clinically significant withdrawal symptoms and concluded that cannabis-dependent adolescents may be particularly vulnerable to physiological symptoms that occur with cannabis withdrawal.
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