Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element (original) (raw)

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor

Sandro Rusconi

The EMBO Journal, 1987

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Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor

Paul Lavender

Molecular Endocrinology, 1992

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Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo

Sam Okret

Proceedings of the National Academy of Sciences, 1981

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Homodimer formation is rate limiting for high affinity binding by the glucocorticoid receptor

Mona Nemer

1992

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Characterization of human glucocorticoid receptor complexes formed with DNA fragments containing or lacking glucocorticoid response elements

John Cidlowski

Biochemistry, 1989

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Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements

Torleif Härd

Journal of Biomolecular NMR, 1991

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Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA

John Cidlowski

Proceedings of the National Academy of Sciences, 1987

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Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains

Sam Okret

Proceedings of the National Academy of Sciences, 1982

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Evaluation of the Role of Ligand and Thermal Activation on Specific DNA Binding by in Vitro Synthesized Human Glucocorticoid Receptor

John Cidlowski

Molecular Endocrinology - MOL ENDOCRINOL, 1991

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Affinity of interactions between human glucocorticoid receptors and DNA: at physiologic ionic strength, stable binding occurs only with DNAs containing partially symmetric glucocorticoid response elements

John Cidlowski

Biochemistry, 1990

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A functional glucocorticoid-responsive unit composed of two overlapping inactive receptor-binding sites: evidence for formation of a receptor tetramer

Miguel Beato

Molecular and cellular biology, 1994

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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

Miles Pufall

Science, 2009

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The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Miles Pufall

Nature Structural & Molecular Biology, 2013

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Characterization and sequence-specific binding to mouse tumor virus DNA of purified activated human glucocorticoid receptor

Oddmund Bakke

Biochemistry, 1987

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Glucocorticoid Receptor Homodimers and Glucocorticoid-Mineralocorticoid Receptor Heterodimers Form in the Cytoplasm through Alternative Dimerization Interfaces

robert hache

Molecular and Cellular Biology, 2001

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Unspecific DNA binding of the DNA binding domain of the glucocorticoid receptor studied with flow linear dichroism

K. Dahlman

FEBS Letters, 1989

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Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA

Rolf Boelens

Journal of Molecular Biology, 2000

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Involvement of a low molecular weight component(s) in the mechanism of action of the glucocorticoid receptor

Max H Cake

Biochemical and Biophysical Research Communications, 1976

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Structural Determinants of a Glucocorticoid Receptor Recognition Element

Steven Nordeen

Molecular Endocrinology, 1990

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Abrogation of Glucocorticoid Receptor Dimerization Correlates with Dissociated Glucocorticoid Behavior of Compound A

Donita Africander

Journal of Biological Chemistry, 2010

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A Single Amino Acid Change in the First Zinc Finger of the DNA Binding Domain of the Glucocorticoid Receptor Regulates Differential Promoter Selectivity

John Cidlowski

Journal of Biological Chemistry, 2004

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Antibodies to Steroid Receptor Deoxyribonucleic Acid Binding Domains and their Reactivity with the Human Glucocorticoid Receptor

John Cidlowski

Molecular Endocrinology, 1988

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Functional analysis of the purified glucocorticoid receptor

Ann-charlotte Wikström

Journal of Steroid Biochemistry, 1986

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Glucocorticoid receptor binding to calf thymus DNA. 2. Role of a DNA-binding activity factor in receptor heterogeneity and a multistep mechanism of receptor activation

Stoney Simons

Biochemistry, 1990

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RNA binding to the untransformed glucocorticoid receptor

Ioannis Economidis

European Journal of Biochemistry, 1988

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Differences in Nuclear Retention Characteristics of Agonist-Activated Glucocorticoid Receptor May Determine Specific Responses

Adali Pecci

Experimental Cell Research, 2002

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Molecular genetic dissection of glucocorticoid receptor function in vivo

J. Tuckermann

Zeitschrift für Rheumatologie, 2000

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A Novel Point Mutation in the DNA-Binding Domain (DBD) of the Human Glucocorticoid Receptor Causes Primary Generalized Glucocorticoid Resistance by Disrupting the Hydrophobic Structure of its DBD

Nicolas Nicolaides

The Journal of Clinical Endocrinology & Metabolism, 2013

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