Age-related variations in the neuroendocrine control, more than impaired receptor sensitivity, cause the reduction in the GH-releasing activity of GHRPs in human aging (original) (raw)

Low Hexarelin dose and pyridostigmine have additive effect and potentiate to the same extent the GHRH-induced GH response in man

Roberta Giordano

Clinical Endocrinology, 1997

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Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects

S. Grottoli

The Journal of Clinical Endocrinology & Metabolism, 1994

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Mechanisms underlying the negative growth hormone (GH) autofeedback on the GH-releasing effect of hexarelin in man

L. Di Vito

Metabolism, 1997

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Hexarelin, a potent GHRP analogue: Interactions with GHRH and clonidine in young and aged dogs

B. Imbimbo

Peptides, 1995

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Pyridostigmine partially restores the GH responsiveness to GHRH in normal aging

Mario Nicolosi

European Journal of Endocrinology, 1990

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Comparisons among old and new provocative tests of GH secretion in 178 normal adults

S. Grottoli

European Journal of Endocrinology, 2000

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Acute administration of hexarelin stimulates GH secretion during day and night in normal men

Marco Cappa

Clinical Endocrinology, 1997

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Acute cardiovascular and hormonal effects of GH and hexarelin, a synthetic GH-releasing peptide, in humans

Maria Rosa Valetto

Journal of Endocrinological Investigation, 1999

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The GH, prolactin, ACTH and cortisol responses to Hexarelin, a synthetic hexapeptide, undergo different age-related variations

L. Di Vito

European Journal of Endocrinology, 1997

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Hexarelin-induced growth hormone response in short stature. Comparison with growth hormone-releasing hormone plus pyridostigmine and arginine plus estrogen

Graziano Grugni

Journal of Endocrinological Investigation, 1999

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Pubblicazione 15 Difference in growth hormone response to growth hormone-releasing hormone

Antonio Giovanni Solimando

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Hexarelin [His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH2], a new GH-releasing peptide, is biologically active in male and female rats

B. Imbimbo

Endocrine

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Interaction of the growth hormone releasing peptide hexarelin with somatostatin

H. Koppeschaar

Clinical Endocrinology, 1997

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Low Dose Hexarelin and Growth Hormone (GH)-Releasing Hormone as a Diagnostic Tool for the Diagnosis of GH Deficiency in Adults: Comparison with Insulin-Induced Hypoglycemia Test 1

Chiara Cosci, Maurizio Gasperi

The Journal of Clinical Endocrinology & Metabolism, 1999

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GH-related and extra-endocrine actions of GH secretagogues in aging

V. Locatelli

Neurobiology of Aging, 2002

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Circulating non-22 kDa growth hormone isoforms after a repeated GHRH stimulus in normal subjects

Alejandro Vela

Growth Hormone & IGF Research, 2005

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In VivoSemiquantification of Hypothalamic Growth Hormone-Releasing Hormone (GHRH) Output in Humans: Evidence for Relative GHRH Deficiency in Aging*

Ariel Barkan

The Journal of Clinical Endocrinology and Metabolism, 1999

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Effect of simultaneous administration of GHRH (1–40) and TRH on GH, PRL and TSH secretion in normal man

Roberto Attanasio

Journal of Endocrinological Investigation, 1986

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Effects of GH on the Aging Process in Several Organs: Mechanisms of Action

Jesus Tresguerres

International Journal of Molecular Sciences, 2022

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d-Lys-GHRP-6 does not modify the endocrine response to acylated ghrelin or hexarelin in humans

Flavia Prodam

Neuropeptides, 2007

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Pharmacokinetics and pharmacodynamics of GH: dependence on route and dosage of administration

Christian Strasburger

European Journal of Endocrinology, 2007

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The role of cholinergic tone in modulating the growth hormone response to growth hormone-releasing hormone in normal man

Angela Girelli

Metabolism, 1991

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Growth hormone-releasing activity of hexarelin in humans

L. Benso

European Journal of Clinical Pharmacology, 1994

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Endogenous growth hormone (GH)-releasing hormone is required for GH responses to pharmacological stimuli

Ariel Barkan

Journal of Clinical Investigation, 1996

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The Impact of Cranial Irradiation on GH Responsiveness to GHRH Plus GH-Releasing Peptide-6

Sandra Pekic Djurdjevic

The Journal of Clinical Endocrinology & Metabolism, 2002

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The negative GH auto-feedback in childhood: Effects of rhGH and/or GHRH on the somatotroph response to GHRH or hexarelin, a peptidyl GH secretagogue, in children

Maria Rosa Valetto

Journal of Endocrinological Investigation, 2000

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Lack of effect of hexarelin on TRH-induced TSH response in normal adult man

B. Imbimbo

Journal of Endocrinological Investigation, 1998

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Aging-Related Growth Hormone (GH) Decrease Is a Selective Hypothalamic GH-Releasing Hormone Pulse Amplitude Mediated Phenomenon

Ariel Barkan

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2001

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Mechanism of action of Hexarelin. I. Growth hormone-releasing activity in the rat

V. Locatelli

European Journal of Endocrinology, 1996

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Differences in Serum GH Cut-Off Values for Pharmacological Tests of GH Secretion Depend on the Serum GH Method

Mariana Costanzo

Hormone Research in Paediatrics, 2006

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Growth hormone and aging

Jesus Tresguerres

Homo-journal of Comparative Human Biology, 2003

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GH-releasing activity of hexarelin, a new growth hormone releasing peptide, in infant and adult rats

V. Locatelli

Life Sciences, 1994

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