Bacteriological Profile of Ear Infections and Its Antibiotic Susceptibility Pattern in Tertiary Care Hospital Navi Mumbai (original) (raw)
Related papers
https://www.ijhsr.org/IJHSR\_Vol.6\_Issue.3\_March2016/11.pdf, 2016
Introduction: Chronic suppurative otitis media (CSOM) is the most common infection of the ear characterized by recurrent, purulent discharge from the middle ear through a nonintact tympanic membrane. Its incidence has remained relatively higher in developing countries Aim/Objectives: This study was carried out in department of Microbiology, Dr.S.C.G.M.C, Nanded to determine bacteriological profile and its antibiotic susceptibility in patients with CSOM Materials & Methods: A total of 470 patientsaged 2-60 years admitted to ENT ward from July 2014 to April 2015 were studied. Ear swabs were taken and cultured aerobically on blood agar and Mac Conkeyagar. The organisms isolated were identified by standard microbiological methods and antibiotic sensitivity pattern was determined Results: Out of 470 patients, 245(52.12%) were female and 225(47.87%) were male. Peak prevalence of otitis media was documented in age group 2-10 years (39.41%). Amongst 470 ear swabs, 460(97.87%) were culture positive and 30(6.52%) were having 2 isolates. Pseudomonas aeruginosa (37.95%) was the commonest isolate followed by Staphylococcus aureus (21.83%), Coagulase Negative Staphylococcus (18.16%), Klebsiella pneumoniae (15.51%) and Escherichia coli (8.36%). Antibiotics sensitive to P. aeruginosa were Imipenem (100%), Gentamicin (65.2%) and Tobramycin (61.7%) and those resistant were Ceftazidime (71.6%) and Piperacillin (59%). Both K. pneumoniae and E. Coli species showed highest sensitivity to Amikacin (96.8%) and Ciprofloxacin (65.3%) and resistance to Amoxyclav (62.2%), Cefotaxime (61.8%) and Ceftriaxone (61.3%). Amongst Gram positive isolates, Vancomycin (100%), Clindamycin (64.3%) and Cefoxitin (53.9%) were highly sensitive and Penicillin (11.2%) was most resistant drug Conclusion: Routine use of topical antibiotics for any case of CSOM as empirical therapy must be reviewed and judicial use of antibiotics is recommended to minimise antibiotic resistance
European Journal of Medical and Health Sciences
Children are more susceptible to ear infection than adults worldwide especially in developing countries. In Bangladesh like other developing countries antibiotics is a common choice of treatment in an ear infection. This study was sought to determine causative agents both in right and left ear infection and their antibacterial susceptibility pattern from patients with an ear infection. Specimens of ear discharge were collected aseptically using a sterile swab and cultured on MacConkey's agar, blood agar and chocolate agar. After inoculating on appropriate culture media bacterial isolates were identified by their colony morphology, culture characteristics, Gram reaction and biochemical tests. In this study, a total of 70 positive cases of patients were included. Among these 27 (38.6%) were male, and 43(61.4%) were female. The prevalence of ear infection was significantly high in females (61.4%) than males (38.6%). The predominant bacterial isolates from positive culture were Staphylococcus aureus 43(61.4%), followed by Pseudomonas spp., 13 (18.6%), Streptococcus spp., 8(11.4%), Proteus spp., 5(7.2%), and Klebsiella spp., 1(1.4%). The antibacterial agent like Amikacin and Gentamicin showed high level of antibacterial effect on all identified bacterial isolates. On the other hand, 98.6% of isolates were found highly resistant to Co-Trimoxazole and Flucoxacillin. Moreover, Streptococcus spp., Proteus spp., Klebsiella spp., and Pseudomonas spp., were highly resistant to multiple drugs (more than 4). A high degree of antibiotic resistance was observed among most of the drugs used in this study. However, Amikacin and Gentamicin were highly effective against the isolated bacterial species. Therefore, culture and susceptibility tests are vital for the appropriate treatment of ear infection.
IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain
Objective: To isolate and identify various bacterial pathogens in positive ear swab cultures of CSOM cases and to determine the antibiotic sensitivity pattern of different bacterial species identified. Study design: Prospective study Setting: J. L. N. Hospital & Research Centre, Bhilai (C.G). Materials and Method: The study was done on the population of Bhilai and surrounding region. A sample size of 120 cases attending the ENT OPD with the diagnosis of Chronic Suppurative Otitis Media and active ear discharge were included in the study. Detailed history, general physical examination, local systemic examination was done along with aural swab for Gram's staining and aerobic bacterial culture and drug sensitivity. The data were then compared with the relevant & available literature. Results: Most of the patients were in the age group of 11-20 years (38.33%), followed by 21-30 years age group (31.67%). More males (60%) were affected by the disease than females (40%). Unilateral (59.16%) infection was more common than bilateral (40.83%). Incidence of monobacterial (90%) etiology was more common than polymicrobial (9.1%). Staphylococcus aureus 67 (51.53%) was the most commonly isolated bacteria followed by the Pseudomonas 26 (20%). Antibiogram showed the most effective drugs in the present study are clindamycin, cotrimoxazole, ciprofloxacin, amikacin, chloramphenicol and ceftazidime Conclusion: Staphylococcus aureus is the most common pathogen isolated, followed by Pseudomonas. Clindamycin was the most effective antibiotic followed by cotrimoxazole, ciprofloxacin, amikacin, chloramphenicol and ceftazidime. Antibiotic sensitivity of the organisms varies according to geographical area and local practice regarding the choice of antibiotics. A continuous and periodic evaluation of microbiological pattern and their antibiotic sensitivity pattern in local area is helpful in prescribing empirical antibiotics for successful treatment of otitis media and thus minimizing its complications and emergence of resistant strains.
IP International Journal of Medical Microbiology and Tropical Diseases, 2022
Nearly 0.065-0.33 billion people suffer from ear infections leading to loss of hearing in 60% of them. As the middle ear is in close proximity to the brain, infections can lead to intracranial complications. Inappropriate use of antibiotics in these situations can lead to multi drug resistant bacterial strains. Hence, the knowledge of commonest bacteria causing these infections along with its susceptibility pattern remains a key to unravel the void left in otological microbiome.: Aretrospective analysis of samples obtained from middle ear infections were analyzed for a period of 4 months (2019) at the Department of Microbiology, SRIHER using Hospital information system. The results of microbiological profile and their susceptibility pattern were tabulated and statistically analyzed.: Out of 325 samples enrolled, 302 samples grew pathogens(GPC:122,GNB:186, Fungi:17 & 23 of them grew more than 1 pathogen). The microbiological profile of 325 pathogens were: Pseudomonas aeruginosa 41.8%...
SpringerPlus, 2016
Ear infection linked with frequent antibiotic prescription, hearing impairment, severe disability and death is a public health threat in developing countries. However, there is scarcity of documented data in the study area. Therefore, this study aimed at determining bacterial etiologic agents and their antimicrobial susceptibility patterns among patients of all age groups referred to Bahir Dar Regional Health Research Laboratory Center. Retrospective data recorded on culture and antimicrobial susceptibility profile were retrieved for analysis. Pus swabs from discharging ears collected and processed for aerobic bacteria culture and susceptibility testing. Of the total 368 pus swab samples processed, 296 (80.4 %) were culture positive. Of which, 289 (97.6 %) were bacteria and 7 (2.4 %) were yeast cells. The proportion of ear infection was higher in males (92.7 %) than females (65 %) (P = 0.014). The frequency of ear infection below 21 years of age was 65.2 %. The predominant isolate was Pseudomonas aeruginosa (29.7 %) followed by Staphylococcus aureus (26.3 %) and Proteus spp. (21.9 %). High level of antimicrobial resistance rates were observed for amoxicillin/clavulanic acid, ampicillin and penicillin whereas ciprofloxacin, ceftriaxone, chloramphenicol, cotrimoxazole, gentamicin and amikacin were found effective against the isolated bacteria. Aerobic bacterial otitis media linked with high levels of resistance against amoxicillin/clavulanic acid and ampicillin is major health problem in the study area. Moreover, considerable level of oxacillin resistant S. aureus suggests the diffusion of methicillin resistant S. aureus in the community. Therefore, treatment of otitis media in the study area needs to be guided by antibiotic susceptibility testing of isolates.
2016
Introduction: Chronic Suppurative Otitis Media (CSOM) takes a lot of time in the hospital outdoors and operation theatres. It is a chronic disease which is associated with irreversible sequelae and serious intracranial and extracranial complications. Henceforth early & effective treatment needs to be instituted to avoid such complications. Materials & Methods: This study was planned at a tertiary care medical college to assess the bacterial etiology and antibiotic susceptibility profile of CSOM cases and to draw comparison with similar studies throughout India over the last four years. Isolation and identification of pathogen was done using aerobic culture followed by standard biochemical tests and antimicrobial susceptibility testing for commonly used antimicrobials. Results: The commonest pathogens isolated were Pseudomonas aeruginosa, Staphylococus aureus, Klebsiella spp., Escherichia coli, Coagulase Negative Staphylococci (CONS) and other gram negative rods mostly showing susceptibility to high end antibiotics like beta lactam-beta lactamase inhibitor, Carbapenems, Fourth generation cephalosporins & Glycopeptides. Conclusion: There is wide variation in antibiotic sensitivity profile over varied geographical areas and populations throughout the country. For better management of this disease, clinical classification as well as antibiotic susceptibility testing of the organisms is essential for making the right choice of antibiotics. The high rate of multiple drug resistance as well as high level of resistance to individual antibiotics is a cause of concern.
International Journal of Otorhinolaryngology and Head and Neck Surgery, 2019
Background: Chronic suppurative otitis media (CSOM) is a common chronic ear disease and a major health problem in developing countries causing deafness and life threatening complications like meningitis and brain abscess. Early and effective treatment based on the knowledge of causative organism and their antibiotic sensitivity is essential for immediate clinical recovery. Methods: Total of 152 clinically diagnosed patients with CSOM safe were enrolled in the study and two swab of the discharge ear were obtained from each patient under aseptic precaution. Microbiological study was done according to standard operative guidelines. Results: Out of 152 patients 93 male and 59 were female, majority of the patient seen below 30 year of age. Most common organism found was Staphylococcus aureus (43.2%) and Pseudomonas aeruginosa (27.9%). Staphylococcus aureus was sensitive to vancomycin (98%) and linezolide (100%) and Pseudomonas aeruginosa was found highly sensitive to Imipenem cilastin (84.85%) and Imipenem (66.7%). Conclusions: In our study gram positive Staphylococcus aureus (43.2%) and gram negative bacilli P. aeuroginosa (27.9%) was the most common organism was found and this P. aeruginosa were hospital acquired infections. We found out high resistant to Cefepime, ceftazidime, ciprofloxacin and levofloxacin and aztreonam.
2020
Background: Chronic suppurative otitis media (CSOM) is defined as a persistent infection of the middle ear with a perforated tympanic membrane and draining exudate for more than 6 weeks. Information about the organism responsible for COSM and their antibiotic susceptibility pattern is an important for effective treatment. Aim: This study aims to develop protocol for empirical treatment by determining aerobic bacterial profile and antibiotics susceptibility in patients of chronic suppurative otitis media (CSOM) at a secondary care hospital in North India. Material and Methods: A cross-sectional study was conducted at ENT department of the secondary care hospital in North India on 85 patients, middle ear discharge sample was collected under strict aseptic conditions and antibiotic susceptibility done as per Clinical Laboratory Standards Institute guidelines. Result: 85 ear swabs were collected, and 89 bacterial isolates were identified, of which 62 (72.94%) sample with mono-microbial ...