original ) (raw )In Lncap Cells Inhibition of Bcl-2 by Antisense Oligonucleotides Results in Compensatory Changes Involving Apoptosis, Transcription and Immunoregulation
Marvin Rubenstein
Enliven: Journal of Genetics, Molecular and Cellular Biology, 2014
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In LNCaP Cells Inhibition of BCL-2 by Antisense Oligonucleonucleotides Results in Compensatory Changes in Apoptosis
Peertechz Journals
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Not All Regulators of Apoptosis are Equally Affected by Compensation Following BCL-2 Suppression by Antisense Oligonucleotides: A Review
Marvin Rubenstein
Cancer Science & Research, 2019
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Bispecific Antisense Oligonucleotides have Activity Comparable to Monospecifics in Inhibiting Expression of BCL-2 in LNCaP Cells
Marvin Rubenstein
In Vivo, 2010
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Oligonucleotide suppression of bcl-2 in LNCaP cells is compensated by increased androgen sensitivity, p53 and oncogene activity, and suppressed caspase-3
Marvin Rubenstein
Medical oncology (Northwood, London, England), 2013
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Combination chemotherapy employing bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and bcl-2 for the treatment of prostate tumors
Marvin Rubenstein
Medical Oncology, 2007
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A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells
F. Natt
Clinical cancer research : an official journal of the American Association for Cancer Research, 2000
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Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes
Palma Rocchi
BJU International, 2006
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A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells
Palma Rocchi
Molecular Cancer Therapeutics, 2005
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In LNCaP cells enhanced expression of the androgen receptor compensates for Bcl-2 suppression by antisense oligonucleotides
Marvin Rubenstein
Therapeutic advances in urology, 2011
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Suppression of Bcl-2 by Antisense Oligonucleotides Results in Compensation and Enhanced Tumor Proliferation Involving KI-67
Marvin Rubenstein
Cancer Science & Research: Open Access, 2015
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Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins
Annemarie Ziegler
JNCI Journal of the National Cancer Institute, 2001
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Following Inhibition of BCL-2 by Antisense Oligonucleotides Compensatory Suppression of Apoptosis Involves the Direct Signal Transduction Pathway of LNCaP Cells
Marvin Rubenstein
Open Journal of Apoptosis, 2015
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Altered Oncogene Activity Contributes to Compensation for Antisense Suppression of Bcl-2 and Tumor Resistance
Marvin Rubenstein
Open Journal of Apoptosis, 2015
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Treatment of MCF-7 breast cancer cells employing mono- and bispecific antisense oligonucleotides having binding specificity toward proteins associated with autocrine regulated growth and BCL-2
Marvin Rubenstein
Medical Oncology, 2007
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Differentiated prostatic antigen expression in LNCaP cells following treatment with bispecific antisense oligonucleotides directed against BCL-2 and EGFR
Marvin Rubenstein
Medical oncology (Northwood, London, England), 2012
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No compensation in VEGF expression follows antisense suppression of BCL-2 activity
Marvin Rubenstein
In vivo (Athens, Greece)
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Antisense RNA Down-Regulation of bcl-2 Expression in DU145 Prostate Cancer Cells Does Not Diminish the Cytostatic Effects of G3139 (Oblimersen)
Johnathan Lai
Clinical Cancer Research, 2004
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Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence
Annemarie Ziegler
JNCI Journal of the National Cancer Institute, 1997
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Bax expression remains unchanged following antisense treatment directed against BCL-2
Marvin Rubenstein
Medical Oncology, 2011
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In LNCaP cells enhanced expression of both androgen receptor and costimulatory protein p300 compensate for antisense oligonucleotide suppression of bcl-2
Marvin Rubenstein
Therapeutic advances in urology, 2011
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Contributing to Tumor Resistance
Marvin Rubenstein
2016
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Effect of Antisense Oligonucleotides Directed Against BCL-2 on Immunotherapy Markers PD-1, PD-L1 and CDK-12 IN LNCaP Cells - A Human Derived Prostate Cancer Line Likely Susceptible to Immunotherapy is Altered by Treatment
Marvin Rubenstein
Cancer Science & Research, 2019
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Combined blockade of protein kinase A and bcl-2 by antisense strategy induces apoptosis and inhibits tumor growth and angiogenesis
V. Damiano
Clinical cancer research : an official journal of the American Association for Cancer Research, 2001
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Enhanced expression of bcl-2 following antisense oligonucleotide mediated growth factor deprivation
Marvin Rubenstein
Medical Oncology, 1997
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Effect of Antisense Mediated BCL-2 Suppression on the Expression of the Androgen Receptor and Coactivating p300 and CREB Binding Proteins
Marvin Rubenstein
The Open Access Journal of Science and Technology, 2013
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ARTICLES Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl2 Coding Sequence
Gerd Luedke , Annemarie Ziegler
2000
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ADDITIONAL MECHANISMS BY WHICH NON-TARGETED GENES COMPENSATE FOR SPECIFIC GENE THERAPY DIRECTED TOWARDS BCL-2 IN A PROSTATE CANCER MODEL A Summary
Marvin Rubenstein
SPG BioMed, 2018
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Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides
Helmut Klocker
Cancer Gene Therapy, 2000
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BCL-XL Antisense Treatment Induces Apoptosis in Breast Carcinoma Cells
Stephen Leech
International Journal of Cancer, 2000
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Antitumor efficacy of oblimersen Bcl-2 antisense oligonucleotide alone and in combination with vinorelbine in xenograft models of human non-small cell lung cancer
Gwyn Bebb
Clinical cancer research : an official journal of the American Association for Cancer Research, 2004
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The role of antisense oligonucleotides in the treatment of bladder cancer
Kate Williamson
Urological Research, 2002
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The Effect of Antisense BCL-2 Oligonucleotides on BCL-2 Protein Expression and Apoptosis in Human Bladder Transitional Cell Carcinoma
Neil Anderson
The Journal of Urology, 2001
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