Prediction of depression and psychometric evaluation of the Beck depression Inventory-II (BDI-II) among adults on highly active antiretroviral therapy in Maiduguri (original) (raw)

Prevalence, correlates and under-diagnosis of clinical depression among adults on highly active antiretroviral therapy in a Tertiary Health Institution in northeastern Nigeria

Journal of Public Health in Africa, 2014

Clinical depression is a highly debilitating illness, which is often under-diagnosed and negatively impacts on the quality of life of its sufferers. When it co-exists with other medical conditions, its effect is even more incapacitating. Undiagnosed depression in the context of HIV infection leads to accelerated decline in CD4+ cell counts with concomitant increase in the viral load and poor adherence to the antiretroviral medications which lead to viral mutation and the evolution of resistant strains. This study examined the prevalence of depression, its correlates and the frequency of the diagnosis of the condition among HIV+ subjects on highly active antiretroviral therapy (HAART) by the internists and general physicians at the University of Maiduguri Teaching Hospital in Northeastern Nigeria.

Prevalence of Depression and Associated Factors in HIV-Positive Adults Attending an Antiretroviral Clinic in Jos, Nigeria

2019

Clinical depression has been associated with various chronic disease conditions. The chronic course of HIV, fostered by the use of antiretroviral therapy in infected patients, puts them at risk of developing clinical depression which unfortunately, is often underdiagnosed and therefore undertreated. The study estimated the prevalence of depression and associated factors amongst adult patients receiving antiretroviral therapy in a clinic in Jos, using the PHQ-9 questionnaire. Three hundred and fourteen patients with a mean age of 45 ± 10 years were enrolled in a descriptive cross-sectional study. There were 63 males and 251 females, with mean known duration of HIV infection of 11 ± 4 years. Depression was found to be common in the group. Thirty one percent of the patients had depression, and of these, 83 (85%) had mild depression while 12 (12%) had moderate depression and 3 (3%) had moderately severe depression. The factors associated with depression in these patients were analysed u...

Prevalence of and risk factors for depressive symptoms among people living with HIV/AIDS receiving antiretroviral treatment in Nigeria

Background: Depression is a common mental disorder (CMD) with significant contributions to the burden of disease. It can lead to high social, economic and individual costs because it accounts for onethird of the days missed at work and a fifth of all primary health-care appointment. Objective: We aimed to explore the prevalence of and risk factors for depressive symptoms among people living with HIV/AIDS (PLWHA) receiving antiretroviral treatment (ART) in Kebbi State, Nigeria. Method: A cross-sectional study evaluating adult PLWHA receiving ART in three designated clinical hospitals was conducted. The validated Beck Depression Inventory (BDI) was used to assess depressive symptoms, ineligible participants. Result: Multinomial regression analysis was used to explore the risk factors for depressive symptoms. 348 participants were finally included in all analyses. 40.3% were found to have depressive symptoms with 13.7% having mild depressive symptoms and 26.6% having moderate to severe depressive symptoms. Conclusion: The results of multinomial regression analysis suggested that being married or living with a partner, recent experience of ART-related side effects, and/or history of HCV infection were positively associated with mild depressive symptoms, while increasing age was positively associated with moderate to severe depressive symptoms.

Prevalence of depression and associated factors among HIV/AIDS patients attending antiretroviral therapy clinic at Dessie referral hospital, South Wollo, Ethiopia

International Journal of Mental Health Systems

Introduction Depression is one of the common mental health disorders and predicted to be the second cause of the global health burden by the year 2020. Depression in HIV patients may lead to poor engagement to their HIV care which may finally result in poor treatment outcomes. Therefore, the aim of this study was to assess the prevalence of depression and associated factors among HIV/AIDS patients on ART at Dessie referral hospital. Methods An institution based cross-sectional study was conducted among 395 HIV positive adult patients on antiretroviral treatment from November to January 2019. The study participants were selected by using the systematic random sampling technique among patients who visited the antiretroviral (ART) clinic in the hospital and standardized Patients Health Questionnaire (PHQ-9) was used to measure depression. Descriptive statistics like percentage, median with interquartile range (IQR) was computed and presented in the form of text and table. Binary logist...

Prevalence and Predictors of Major Depression in HIV-Infected Patients on Antiretroviral Therapy in Bamenda, a Semi-Urban Center in Cameroon

PLoS ONE, 2012

Recent blue-ribbon panel reports have concluded that HIV treatment programs in less wealthy countries must integrate mental health identification and treatment into normal HIV clinical care and that research on mental health and HIV in these settings should be a high priority. We assessed the epidemiology of depression in HIV patients on antiretroviral therapy in a small urban setting in Cameroon by administering a structured interview for depression to 400 patients consecutively attending the Bamenda Regional Hospital AIDS Treatment Center. One in five participants met lifetime criteria for MDD, and 7% had MDD within the prior year. Only 33% had ever spoken with a health professional about depression, and 12% reported ever having received depression treatment that was helpful or effective. Over 2/3 with past-year MDD had severe or very severe episodes. The number of prior depressive episodes and the number of HIV symptoms were the strongest predictors of past-year MDD. The prevalence of MDD in Cameroon is as high as that of other HIV-associated conditions, such as tuberculosis and Hepatitis B virus, whose care is incorporated into World Health Organization guidelines. The management of depression needs to be incorporated in HIV-care guidelines in Cameroon and other similar settings.

2014 Factor structure of the Beck Depression Inventory-II among South Africans receiving antiretroviral therapy

Considerable evidence suggests that mood disturbance is common among patients living with HIV and may be an important barrier to anti-retroviral therapy (ART) adherence. Thus the assessment of depressed mood is an important and necessary aspect of the experience of persons living with HIV as it may impact the health status of individuals directly and indirectly. We sought to determine the factor structure of the Beck Depression Inventory (BDI) among a sample of 185 South Africans living with HIV and receiving ART. The mean BDI score was 16.5 (SD 12.15) with a range from 0Á50 (out of a possible 63), indicating on average moderate levels of depression. Cronbach's alpha for the total scale was 0.90. Although the four factors had eigenvalues that were technically above 1.0, only three factors could logically be extracted, the combination of which accounted for 47.29% of the variance. These three factors were Cognitive, Affective and Somatic. The results indicate that the BDI-II is a reliable measure of symptoms of depression among persons living with HIV. The factor structure among South Africans receiving ART is similar to that of other samples, although surprisingly, the item assessing appetite disturbance did not load on any factor. The results of the study suggest that the BDI-II is a useful measure among South Africans living with HIV. In the context of the need to rapidly identify depressed mood among persons receiving ART in public health clinics, the BDI may be a useful instrument. We end the paper with certain cautions associated with routine screening.

Depression and Associated Factors Among Adult HIV/AIDS Patients Attending Antiretroviral Therapy at Wolaita Sodo University Teaching and Referral Hospital, Southern Ethiopia

HIV/AIDS (Auckland, N.Z.), 2020

Background Nearly, 350 million people in the world are currently living with depression. Depression happening in PLHIV leads to alteration of economic productivity, decrease of working abilities, social isolation, physical decline and difficulties in solving problems. This study investigates the burden of depression and associated factors on HIV/AIDS patients attending an ART clinic. Methods An institution-based cross-sectional study was implemented from April 1 to May 30, 2019 on a total of 417 HIV-positive patients. Systematic random sampling technique was used to access the study participants. Interviewer-administered structured questionnaire was used for data collection. Data were entered in to EpiData 3.1 and then were exported into Statistical Package for the Social Sciences (SPSS window version 20) for analysis. Results Four hundred ten (410) respondents participated in the study with a response rate of 98.3%. The burden of depression was 50.5% in this study. Male (AOR=1.53; ...

Prevalence and pattern of depression among HIV positive patients on treatment at the ART clinic of UDUTH , Sokoto , Nigeria

2019

Background: Depression is one of the most frequently observed psychiatric disorder among patients with HIV/AIDS and it has been associated with increased risky behaviors, noncompliance to anti-retroviral treatment, and higher risk for co-morbid survival. Aim: This study was conducted to determine the prevalence and pattern of depression among HIV positive patients on treatment at the ART clinic of UDUTH, Sokoto, Nigeria. Materials and Methods: This was a cross-sectional study among 419 patients (selected by systematic sampling technique) attending the ART clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. A structured interviewer-administered questionnaire was used to collect data on the research variables. Data were analyzed using IBM SPSS version 20 statistical computer software package. Results: Two hundred and twenty-seven (54.2%) of the 419 participants were identified as having depression, with 179 (42.7%) having mild depression, 46 (11.0%) having modera...

PREVALENCE AND SEVERITY OF DEPRESSION AMONG PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS IN YENAGOA, SOUTHERN NIGERIA

Background: Depression is a mental health condition that affects approximately 350 million people worldwide. People living with HIV and AIDS (PLWHA) are at increased risk of developing this condition. Identification of location-specific factors is crucial to minimizing this presentation in this sub-population. Aim: The aim of this study was to measure the prevalence, severity, and associated sociodemographic and comorbidity of depression among people living with HIV and AIDS in a laboratory setting in Yenagoa, southern Nigeria. Methods: This is a cross-sectional study carried out on 282 PLWHA, aged 18 years and over. They receive HIV screening services in the laboratory of the Federal Medical Center, Yenagoa from March to April 2017. Sociodemographic data of respondents and selected comorbidities were collected using a modified structured questionnaire from the World Health Organization STEPS tool. Retrieving CD4+ count results from the laboratory registry, and height, weight, and body mass index (BMI) were measured. The presence of depression was assessed using the Patients Health Questionnaire-9 tool and performed a multivariate logistic regression analysis to identify factors associated with depression with a 95% confidence level. Results: The mean age of the respondents was 40±8.8 years and most of them were females 195 (69.2%). Seventy-five (26.6%) of the respondents were depressed, of whom 10 (13.3%) had severe depression, while 41 (54.7%) had mild depression. The most common symptoms of depression were fatigue (30.1%) and dysphoria (28.7%). There was an association between depression and CD4+ count <350 cells/µL with an adjusted odds ratio (aOR) of 2.04 (95% CI: 1.14-3.63) and underweight with an aOR of 2.56 (95%CI: 1.01-6.47), while HAART with an aOR of 0.38 (95% CI: 0.18-0.84) was associated with decreased odds of developing depression. Conclusion: Depression appeared among a significant proportion of people living with HIV and AIDS in Yenagoa, southern Nigeria, and fatigue was the most common symptom of depression. Lack of HAART, low CD4+ count, and being underweight appear to be the major factors negatively associated with depression. There is therefore a need to ensure people living with HIV and AIDS continue to receive HAART to improve CD4+ count and increase BMI.

The impact of comorbid clinical depression on the health-related quality of life of adults on highly active antiretroviral therapy in Maiduguri, northeastern Nigeria

Indian Journal of Psychological Medicine, 2014

INTRODUCTION Depression is a common psychiatric condition that Background: Globally, depression compromises the quality of life (QOL) of people suffering from it. We assessed the impact of comorbid depression on the health-related quality of life (HRQOL) of adults on highly active antiretroviral therapy (HAART) in northeastern Nigeria in this study. Materials and Methods: Three hundred and three adults on HAART were recruited for this study from the ART clinic of the University of Maiduguri Teaching Hospital in northeastern Nigeria. The depressive disorder module of the Composite international diagnostic interview (CIDI version 3.0) and the WHO quality of life instrument (WHOQOL-BREF) were used for the evaluation of depression and quality of life respectively. Results: The prevalence of depression in this study was 19.8%. The depressed respondents rated their HRQOL poorer than their nondepressed counterparts on the physical, psychological, social relationships and environmental domains as well as the global outcome, as shown by these statistically significant findings