Association of MHC and rheumatoid arthritis. Regulatory role of HLA class II molecules in animal models of RA: studies on transgenic/knockout mice (original) (raw)

HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritis

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Modulation of HLA-DQ-restricted collagen-induced arthritis by HLA-DRB1 polymorphism

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Complementation between HLA-DR4 (DRB1∗0401) and specific H2-A molecule in transgenic mice leads to collagen-induced arthritis

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Implications for Rheumatoid Arthritis HLA-DQ8Transgenic Mice: Collagen-Induced Arthritis in Susceptibility/Protection to CD4 and CD8 T Cells in

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Expression of the H2-E molecule mediates protection to collagen-induced arthritis in HLA-DQ8 transgenic mice: role of cytokines

H. Luthra

International Immunology, 1997

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CD4 and CD8 T Cells in Susceptibility/Protection to Collagen-Induced Arthritis in HLA-DQ8-Transgenic Mice: Implications for Rheumatoid Arthritis

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The Journal of Immunology, 2002

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Polymorphism of the MHC class II Eb gene determines the protection against collagen-induced arthritis

Harvinder Luthra, Eric Zanelli

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Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis

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CD4 and CD8 T Cells in Susceptibility/Protection to Collagen-Induced Arthritis in HLA-DQ8Transgenic Mice: Implications for Rheumatoid Arthritis1

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2002

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An HLA-DRB1∗0402 derived peptide (HV3 65-79) prevents collagen-induced arthritis in HLA-DQ8 transgenic mice

Chella David

Human Immunology, 1999

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MHC Class II Derived Recombinant T Cell Receptor Ligands Protect DBA/1LacJ Mice from Collagen-Induced Arthritis

Arthur Vandenbark

The Journal of Immunology, 2008

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Trans heterodimer between two non-arthritis-associated HLA alleles can predispose to arthritis in humanized mice

Harvinder Luthra

Arthritis & Rheumatism, 2011

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No support for HLA-DQ encoded susceptibility in rheumatoid arthritis

Niek Vries

Arthritis & Rheumatism, 1999

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Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model1

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Breaking T cell tolerance against self-type II collagen in HLA-DR4 transgenic mice and development of autoimmune arthritis

Balik Dzhambazov

Arthritis & Rheumatism, 2010

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Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model

Lucia Mori

The Journal of Immunology, 2003

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Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice

Jonathan Rothbard, L. Fugger

Proceedings of the National Academy of Sciences, 1998

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C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells

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Annals of the rheumatic diseases, 2013

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HLA-DRB1*0402 (DW10) transgene protects collagen-induced arthritis-susceptible H2Aq and DRB1*0401 (DW4) transgenic mice from arthritis

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Journal of immunology (Baltimore, Md. : 1950), 2003

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Differential MHC Class II-Mediated Presentation of Rheumatoid Arthritis Autoantigens by Human Dendritic Cells and Macrophages1

Yu Teng

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Humanized mice as a model for rheumatoid arthritis

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Human leukocyte antigen-DRB1∗1502 (DR2Dw12) transgene reduces incidence and severity of arthritis in mice

H. Luthra

Human Immunology, 1996

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To B or not to B: Role of B cells in pathogenesis of arthritis in HLA transgenic mice

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Journal of Autoimmunity, 2011

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CD74/DQA1 dimers predispose to the development of arthritis in humanized mice

Seetharama Jois

Immunology, 2015

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New humanized HLA–DR4–transgenic mice that mimic the sex bias of rheumatoid arthritis

H. Luthra

Arthritis & Rheumatism, 2006

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