Association of MHC and rheumatoid arthritis. Regulatory role of HLA class II molecules in animal models of RA: studies on transgenic/knockout mice (original ) (raw )HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritis
Chella David
Journal of Clinical Investigation, 1997
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HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis
Gerald Nabozny
Journal of Experimental Medicine, 1996
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Modulation of HLA-DQ-restricted collagen-induced arthritis by HLA-DRB1 polymorphism
Harvinder Luthra
International Immunology, 1998
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Delineating the Role of the HLA-DR4 “Shared Epitope” in Susceptibility versus Resistance to Develop Arthritis
H. Luthra
The Journal of Immunology, 2008
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Complementation between HLA-DR4 (DRB1∗0401) and specific H2-A molecule in transgenic mice leads to collagen-induced arthritis
Harvinder Luthra
Human Immunology, 1999
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Implications for Rheumatoid Arthritis HLA-DQ8Transgenic Mice: Collagen-Induced Arthritis in Susceptibility/Protection to CD4 and CD8 T Cells in
Marshall Behrens
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Expression of the H2-E molecule mediates protection to collagen-induced arthritis in HLA-DQ8 transgenic mice: role of cytokines
H. Luthra
International Immunology, 1997
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CD4 and CD8 T Cells in Susceptibility/Protection to Collagen-Induced Arthritis in HLA-DQ8-Transgenic Mice: Implications for Rheumatoid Arthritis
Harvinder Luthra
The Journal of Immunology, 2002
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Polymorphism of the MHC class II Eb gene determines the protection against collagen-induced arthritis
Harvinder Luthra , Eric Zanelli
Immunogenetics, 1995
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Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis
Takashi Okamoto
Proceedings of the National Academy of Sciences, 2006
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CD4 and CD8 T Cells in Susceptibility/Protection to Collagen-Induced Arthritis in HLA-DQ8Transgenic Mice: Implications for Rheumatoid Arthritis1
Marshall Behrens
2002
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An HLA-DRB1∗0402 derived peptide (HV3 65-79) prevents collagen-induced arthritis in HLA-DQ8 transgenic mice
Chella David
Human Immunology, 1999
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MHC Class II Derived Recombinant T Cell Receptor Ligands Protect DBA/1LacJ Mice from Collagen-Induced Arthritis
Arthur Vandenbark
The Journal of Immunology, 2008
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Trans heterodimer between two non-arthritis-associated HLA alleles can predispose to arthritis in humanized mice
Harvinder Luthra
Arthritis & Rheumatism, 2011
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No support for HLA-DQ encoded susceptibility in rheumatoid arthritis
Niek Vries
Arthritis & Rheumatism, 1999
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Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model1
Kutty Selva Nandakumar
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Breaking T cell tolerance against self-type II collagen in HLA-DR4 transgenic mice and development of autoimmune arthritis
Balik Dzhambazov
Arthritis & Rheumatism, 2010
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Genetic Control of Tolerance to Type II Collagen and Development of Arthritis in an Autologous Collagen-Induced Arthritis Model
Lucia Mori
The Journal of Immunology, 2003
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Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice
Jonathan Rothbard , L. Fugger
Proceedings of the National Academy of Sciences, 1998
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C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells
Kutty Selva Nandakumar
Annals of the rheumatic diseases, 2013
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HLA-DRB1*0402 (DW10) transgene protects collagen-induced arthritis-susceptible H2Aq and DRB1*0401 (DW4) transgenic mice from arthritis
Harvinder Luthra
Journal of immunology (Baltimore, Md. : 1950), 2003
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Differential MHC Class II-Mediated Presentation of Rheumatoid Arthritis Autoantigens by Human Dendritic Cells and Macrophages1
Yu Teng
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Humanized mice as a model for rheumatoid arthritis
Andrew Cope , Chiyoko Sekine , Kayta Kobayashi , Rüdiger Eming , Frances Hall , Grete Sønderstrup
Arthritis research, 2002
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Human leukocyte antigen-DRB1∗1502 (DR2Dw12) transgene reduces incidence and severity of arthritis in mice
H. Luthra
Human Immunology, 1996
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To B or not to B: Role of B cells in pathogenesis of arthritis in HLA transgenic mice
Marshall Behrens
Journal of Autoimmunity, 2011
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CD74/DQA1 dimers predispose to the development of arthritis in humanized mice
Seetharama Jois
Immunology, 2015
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New humanized HLA–DR4–transgenic mice that mimic the sex bias of rheumatoid arthritis
H. Luthra
Arthritis & Rheumatism, 2006
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