Construction of a stress-induced system in Escherichia coli for efficient polyhydroxyalkanoates production (original) (raw)

The study presents a novel stress-induced system in Escherichia coli designed for efficient production of polyhydroxybutyrate (PHB), a biodegradable biopolymer. By engineering E. coli to accumulate PHB without the need for traditional inducers like IPTG, this research demonstrates that recombinant strains can achieve up to 85% PHB of cell dry weight in a short cultivation period. The stress-induced system showcases enhanced responsiveness to environmental changes, paving the way for improved biotechnological applications across various fields.