Synthesis, physico-chemical and antimicrobial screening studies of some transition metal complexes with O:O donor ligands (original) (raw)
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TheScientificWorldJournal, 2013
A series of new coordination complexes of Cu(II), Co(II), Ni(II), Zn(II), Hg(II), Mn(II), and Fe(III) with the Schiff base 3-chloro-N'-[(1E)-(2-hydroxy phenyl)methylene]-6-methoxy-1-benzothiophene-2-carbohydrazide (HL) have been synthesized and characterized by elemental analysis, electrical conductivity measurements, IR spectra, (1)H NMR, mass spectral data, electronic spectra, magnetic susceptibility, ESR spectra, TGA, and Powder XRD data. The Schiff base behaves as tridentate ONO donor ligand and forms the complexes of the type ML2 (metal-ligand) stoichiometry for Cu(II), Co(II), Ni(II), and Mn(II) complexes and ML stoichiometry for Zn(II), Hg(II), and Fe(III) complexes. All the complexes are colored and nonelectrolytes. It is found that Cu(II), Co(II), Ni(II), Mn(II) and Fe(III) complexes have exhibited octahedral geometry whereas Zn(II) and Hg(II) complexes exhibited tetrahedral geometry. The ligand and its metal complexes have been screened for their antibacterial activity...
Asian Journal of Chemistry, 2019
This paper describes the synthesis, spectral studies and antimicrobial properties of the complexes with the formula [M(C30H24N4O2)Cl2], where M = Fe(II), Co(II), Ni(II), Zn(II) and Cu(II). These complexes were prepared by yield effective template condensation of hexamethylenediamine and 2,2-dihydroxyindane-1,3-dione(ninhydrin). The synthesized complexes were characterized by elemental analysis, infrared spectra, thermogravimetric analysis, Mass spectrum, 13C NMR, molar conductance, electronic spectra, magnetic measurements. TGA and X-ray diffraction studies were used to ascertain the crystal structure and thermal stability of the complexes. The antimicrobial properties of complexes against two Gram-positive bacteria and two Gram-negative bacteria were evaluated by Agar well diffusion technique. Streptomycin and chloramphenicol were taken as standard antibiotics. The results shows that some of the complexes have potential to act as antibacterial agents.
Iraqi journal of science, 2020
Binuclear metal complexes of the metal ions Fe (II), Co (II), Ni (II) and Cu (II) were synthesized by the reaction of these metal ions with the imine of benzidine (H2L) as a primary ligand and o-phenylenediammine (OPD) as a secondary ligand in a molar ratio of 2:2:1. The prepared complexes were characterized using CHN elemental analysis, FT-IR, UV-visible, molar conductivity, magnetic susceptibility and TGA-DTA thermogravimetric analysis. All the prepared complexes showed apparent stability and could be stored for months without any appreciable change. According to the results obtained by elemental and spectral analyses, a tetrahedral structure is suggested for all the prepared complexes, except for the copper complex which showed a square planar structure. The antimicrobial activities of these complexes were evaluated against Bacillus spp. (Gram-negative bacteria), Proteus spp. (Gram-positive bacteria) and Aspergillus niger (A. niger, a fungal species). The results showed that all...
2017
A series of Fe(III), Ni(II) and Cu(II) complexes had been synthesized with molecular formula of [Fe(L)(H2 O)2Cl].2H2O, [Ni(L)(H2O)].2H2O and [Cu(L)(H2O)3].2H2O, where L is a Schiff base ligand was derived by condensation of anthranilic acid with 2-hydroxy-benzaldhyde. Structures of the obtained compounds had been characterized using elemental analyses, UV-Vis., FT-IR, magnetic moment and conductivity measurements. Results proposed octahedral geometry for both of Fe(III) and Cu(II) complexes while Ni(II) complex had a square planar geometry. Density Functional Theory (DFT) calculations were performed to confirm the 3D geometry of the compounds and estimate selected electronic parameters (e.g. chemical potential, hardness and electrophilicity index). Moreover free ligand and its metal complexes had been screened for in-vitro antibacterial (Escherichia coli (G-) and Bacillus cereus (G+)) and antifungal (aspergillus fumigatus) activities in terms of the minimum inhibitory concentration ...
Macrocyclic ligands are polydentate ligands containing donor atoms either incorporated or attached to cyclic backbone and showed significance in various biological studies. Tetraaza macrocyclic complexes of transition metals, Ni(II), Cu(II), Fe(III), and Mn(II) were synthesized in methanolic media using template method. These complexes were non-hygroscopic and consist of crystalline solids. Structural identification of these complexes was done using analytical techniques UV-Vis and IR Spectroscopy. The antibacterial activities of macrocyclic complexes (1-6) were screened against both Gram-negative bacteria (Escherichia coli and Vibrio cholerae) and Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus). In the present study we have reported that these synthesized complexes showed slight antibacterial activity except macrocyclic complex (6) which showed moderate antibacterial activity.
2017
A new Schiff base (R,E)-2(dimethylamino)-3-(4-hydroxyphenyl) -N,2,3-trimethyl-N’-(1-ptolylethylidene) butanehydrazide, Tmbh and Mn(II), Ni(II), Co(II), Cu(II) and Zn(II) complexes were synthesized and characterized on the basis of analytical, magnetic, cyclic voltammetric, conducto metric, UV-Visible, TG/DTA, IR, NMR, EPR and mass spectral data. Tmbh acts as a uninegative/neutral bidentate ligand in all the complexes bonding through carbonyl oxygen and azomethine nitrogen. Half field signal observed in the ESR spectrum of Ni(II) complex is indicative of its dimeric nature and the trend in g-values suggests tetragonally distorted octahedral geometries for Co(II), Ni(II) and Cu(II) complexes. All the complexes exhibit irreversible redox behavior. Morphology of Tmbh and the complexes have also been investigated through SEM and powder XRD data. Antimicrobial effects of the ligand and the complexes against the microbes Bacillus subtilis, Escherichia coli, Psuedomonas aeruginosa and Klebs...
2020
The complexes of the type MLXn ,where M=VO(IV), Mn(II), Fe(III), Co(II),Ni(II), Zn(II) and Cd(II) ,X=H 2 O/Cl and L is the schiff base ligand derived from 2,4-dihydroxy -5-acetylacetophenone and 1,4-diaminobutane have been synthesized. All the complexes isolated in solid state, are stable in air and characterized by the elemental analysis, metal content determination, magnetic measurements, thermogravimetric analysis (TGA), IR, and electronic spectral data. The physicochemical data suggest a square pyramidal structure to VO(IV), pseudo octahedral to Cu(II) and an octahedral for Mn(II), Fe(III), Co(II),Ni(II) and Cd(II) complexes. The ligand field parameters have been calculated and related to the electronic environment. The Schiff base and its complexes were screened for their antimicrobial activities against various bacteria and fungi.
Bioinorganic Chemistry and Applications, 2008
The new complexes [M 2 O 5 L 2 (H 2 O) 2 ] · H 2 O (M = Mo, 1; M = W, 2), [RuL 2 (H 2 O) 2 ] · H 2 O (3), [ML 3 ] · xH 2 O (M = Rh, x = 2, 4; M = Ir, x = 1, 5), [RhL 2 (PPh 3 ) 2 ](ClO 4 ) · 2H 2 O (6), [PdL 2 ] · 2H 2 O (7), [PdL(phen)]Cl · H 2 O (8),
Chintan Research Journal (ISSN : 2229-7227\), 2024
In present study the complexes of the type MLXn, where M= Cu(II), Co(II), Ni(II), Zn(II) and X= H 2 O/Cl and L is the schiff base ligand prepared from 2,4-dihydroxy-5-Acetylacetophenone and 1,4-diaminobutane have been synthesized, as they are widely used as chelating ligands in coordination chemistry. All complexes isolated in solid, are stable in air and characterized by the elemental analysis, metal content determination, magnetic measurements, thermo gravimetric analysis (TGA), IR, and electronic spectral data. The physicochemical data suggest a pseudo octahedral structure to Cu(II) and an octahedral for Co(II), Ni(II), and Zn(II) complexes. The ligand field parameters have been calculated and related to the electronic environment. The Schiff base and its complexes were screened for their antimicrobial activities against various microorganisms.