Small solute clearance targets in peritoneal dialysis (original) (raw)

This paper discusses the critical evaluation of small solute clearance targets in peritoneal dialysis (PD) and the necessity of considering these targets in a broader clinical context. It highlights findings from randomized controlled trials that do not support a direct survival advantage from increasing peritoneal small solute clearance, advocating for an integrated assessment of dialysis adequacy that includes other clinical parameters such as hydration status, blood pressure, and nutritional health. The research also underscores the importance of residual renal function and suggests that identical clearance targets can be applied to various forms of peritoneal dialysis.