Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation
Isabelle Six
Oncotarget, 2017
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Roles for the calcium sensing receptor in primary and metastatic cancer
aidan manning
Ejso, 2006
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Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor
Said Kamel, Michel Brazier
Bone, 2009
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Isolation and characterization of a new cell line from a renal carcinoma bone metastasis
Reza Roozafzoon
Anticancer research
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The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases
Philippe Clézardin
Frontiers in Oncology, 2020
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Prostate cancer metastatic to bone has higher expression of the calcium-sensing receptor (CaSR) than primary prostate cancer
Alton Farris
Receptors & clinical investigation
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Calcium Sensing Receptor Modulation for Cancer Therapy
Sudhir Kumar
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Primitive and bone metastatic renal carcinoma cells promote osteoclastogenesis through endothelial cells
Elisabetta Cenni
Anticancer …, 2006
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Bone Metastasis from Renal Cell Carcinoma
oscar valenzuela
International Journal of Molecular Sciences, 2016
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Molecular Pathway for Cancer Metastasis to Bone
Warren Heston
Journal of Biological Chemistry, 2003
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Calcium-Sensing Receptor Antagonist NPS-2143 Inhibits Breast Cancer cell Proliferation, Migration and Invasion via Downregulation of p-ERK1/2, Bcl-2 and Integrin β1 and Induces Caspase 3/7 Activation
Marwah Azaizeh
Advanced Pharmaceutical Bulletin, 2021
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Intracellular Calcium, Endothelial Cells and Angiogenesis
Luca Munaron
Recent Patents on Anti-Cancer Drug Discovery, 2006
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Osteoblasts modulate Ca2+ signaling in bone-metastatic prostate and breast cancer cells
Julia D'Ambrosio
2015
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Role of calcium-sensing receptor in bone biology
Dr. Jawed A siddiqui
Indian Journal of …, 2008
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The calcium-sensing receptor modulates cell adhesion and migration via integrins
Arthur Conigrave
2011
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Calcium-sensing Receptor Modulates Cell Adhesion and Migration via Integrins
Arthur Conigrave
Journal of Biological Chemistry, 2011
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Expression of the calcium receptor in human breast cancer—a potential new marker predicting the risk of bone metastases
Radu Mihai
European Journal of Surgical Oncology the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2006
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Chemotactic and proangiogenic role of calcium sensing receptor is linked to secretion of multiple cytokines and growth factors in breast cancer MDA-MB-231 cells
GUADALUPE MAC�AS CRUZ
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2015
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Extracellular calcium and CaSR drive osteoinduction in mesenchymal stromal cells.
Arlyng González Vázquez
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A temporal examination of calcium signaling in cancer-from tumorigenesis, to immune evasion, and metastasis
Musa Kiyani
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CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment
Youngsook Son
International Journal of Molecular Sciences, 2020
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Molecular Biology of Bone Metastasis
John Chirgwin
Molecular Cancer Therapeutics, 2007
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Calcium-sensing receptor (CaSR) promotes breast cancer by stimulating intracrine actions of parathyroid hormone-related protein
John Wysolmerski
Cancer research, 2016
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Bone Structural Components Regulating Sites of Tumor Metastasis
Scott Guelcher
Current Osteoporosis Reports, 2011
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The calcium sensing receptor: from understanding parathyroid calcium homeostasis to bone metastases
Radu Mihai
Annals of The Royal College of Surgeons of England, 2008
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mTOR inhibitor and bone-targeted drugs break the vicious cycle between clear-cell renal carcinoma and osteoclasts in an in vitro co-culture model
Toni Ibrahim
Journal of Bone Oncology, 2019
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Endothelial Calcium Machinery and Angiogenesis: Understanding Physiology to Interfere with Pathology
Luca Munaron
Current Medicinal Chemistry, 2009
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Cellular and Molecular Mediators of Bone Metastatic Lesions
Michela Rossi
International journal of molecular sciences, 2018
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Renal cell carcinoma in tissue culture secretes nondialyzable product that stimulates bone resorption in organ-cultured mouse calvaria
Börje Ljungberg
Journal of Bone and Mineral Research, 2009
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Implication of the calcium sensing receptor and the Phosphoinositide 3-kinase/Akt pathway in the extracellular calcium-mediated migration of RAW 264.7 osteoclast precursor cells
Michel Brazier
Bone, 2010
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Mitogenic Action of Calcium-Sensing Receptor on Rat Calvarial Osteoblasts
Naibedya Chattopadhyay
Endocrinology, 2004
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Osteosarcoma cell-calcium signaling through tissue factor–factor VIIa complex and factor Xa
Roland Pochet
FEBS Letters, 2007
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