Kinetics of nerve agent hydrolysis by a human plasma enzyme (original) (raw)

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents

Patrick Gillon

Fuel and Energy Abstracts, 2011

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Furthering the Enzymatic Destruction of Nerve Agents

Ilya Elashvili

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Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme

John Cashman

PLoS ONE, 2011

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Enzymatic Hydrolysis of the Chemical Warfare Agent VX and its Neurotoxic Analogues by Organophosphorus Hydrolase

Jan Kolakowski

Biocatalysis and Biotransformation, 1997

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Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review

Richard Sweeney

Toxicology, 2007

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Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

Raanan Margalit

Nature Chemical Biology, 2011

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Stereoselective Hydrolysis of Organophosphate Nerve Agents by the Bacterial Phosphotriesterase

Frank Raushel

Biochemistry, 2010

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Evolved Stereoselective Hydrolases for Broad-Spectrum G-Type Nerve Agent Detoxification

yair simo

Chemistry & Biology, 2012

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Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents

Steve Harvey

Biochemistry, 2012

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Analogues with Fluorescent Leaving Groups for Screening and Selection of Enzymes That Efficiently Hydrolyze Organophosphorus Nerve Agents

Janet Briseño

Journal of Medicinal Chemistry, 2006

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Asymmetric biodegradation of the nerve agents Sarin and VX by human dUTPase: Chemometrics, Molecular Docking and Hybrid QM/MM calculations

Alexandre Alves de Castro

Journal of biomolecular structure & dynamics, 2018

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Catalytic properties of paraoxonase (PON1), a promising catalytic scavenger against poisoning by nerve agents

Denis Josse

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Immobilization of organophosphorus hydrolase for the degradation of organophosphorus nerve agents

soudeh falahati

The Journal of general and applied microbiology, 2016

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Enzymatic Analysis of G- and V-Agents and Their Degradation Products

Ilya Elashvili

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A Rationally Designed Mutant of Plasma Platelet-Activating Factor Acetylhydrolase Hydrolyzes the Organophosphorus Nerve Agent Soman

Richard Sweeney

Biochimica et biophysica acta, 2015

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Rational design of organophosphorus hydrolase with high catalytic efficiency for detoxifying a V-type nerve agent

Young-Su Jeong

Biochemical and biophysical research communications, 2014

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Solvolysis of chemical warfare agent VX is more efficient with hydroxylamine anion: A computational study

Manoj Kesharwani, Shafee Khan, Tusar Bandyopadhyay

Journal of Molecular Graphics and Modelling, 2009

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Progress in the development of enzyme-based nerve agent bioscavengers

Florian Nachon

Chemico-Biological Interactions, 2013

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Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun † , ‡

Philip Potter

Biochemistry, 2007

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Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning

Oksana Lockridge

Journal of Physiology-Paris, 1998

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Structural Insights into the Dual Activities of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase

SAUMIL SHAH

Biochemistry, 2010

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Developing a Bioscavenger Against Organophosphate Nerve Agents

Reed Jacob

2017

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Generic Rapid Analysis of Current and Prospective Nerve Agents and Their Degradation Products

Ilya Elashvili

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A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study

kevin bernal

Molecules, 2021

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Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis

Steve Harvey

Journal of the American Chemical Society, 2013

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A review on analysis methods for nerve agent hydrolysis products

INTAN NADHIRAH BINTI SULAIMAN PP2212067T

Forensic Toxicology, 2019

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Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperatures

Casey Theriot, Amy Grunden

Applied Microbiology and Biotechnology, 2010

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Improving the Catalytic Activity of Hyperthermophilic Pyrococcus horikoshii Prolidase for Detoxification of Organophosphorus Nerve Agents over a Broad Range of Temperatures

Casey Theriot, Amy Grunden

Archaea, 2011

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Improving the Catalytic Activity of HyperthermophilicPyrococcus horikoshiiProlidase for Detoxification of Organophosphorus Nerve Agents over a Broad Range of Temperatures

Amy Grunden

Archaea, 2011

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Innovative Biocatalysts as Tools to Detect and Inactivate Nerve Agents

Ilaria Palchetti

Scientific reports, 2018

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Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX

Eman Ghanem

2007

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The Role of Oximes in the Treatment of Nerve Agent Poisoning in Civilian Casualties

Allister Vale, Timothy Marrs

Toxicological Reviews, 2006

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