Amino acids as regulators of gene expression at the level of mRNA translation (original) (raw)

New functions for amino acids: effects on gene transcription and translation

Scot Kimball

The American journal of clinical nutrition, 2006

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Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation

Miri Stolovich-Rain, Oded Meyuhas

2001

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In vitro activity of human translation initiation factor eIF4B is not affected by phosphomimetic amino acid substitutions S422D and S422E

Sergey Dmitriev

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Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI

Nahum Sonenberg

The EMBO Journal, 2000

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Control of Paip1-Eukayrotic Translation Initiation Factor 3 Interaction by Amino Acids through S6 Kinase

Marie-pierre Bousquet-dubouch

Molecular and Cellular Biology, 2014

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The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

Vinay Pathak

Molecular and Cellular Biology, 1989

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Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine

Martha Stipanuk

Scientific Reports, 2018

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Regulation of mRNA translation by signaling pathways

Philippe P Roux

Cold Spring Harbor perspectives in biology, 2012

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Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

Alan Hinnebusch

Cell, 2009

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Regulation of global and specific mRNA translation by the mTOR signaling pathway

Philippe P Roux

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Regulation of translation initiation factors by signal transduction

Adri Thomas

European Journal of Biochemistry, 1998

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Mechanisms governing the control of mRNA translation

Amit Meller

Physical Biology, 2010

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Phosphorylation of the Eukaryotic Translation Initiation Factor eIF4E Contributes to Its Transformation and mRNA Transport Activities

Ivan Topisirovic

Cancer Research, 2004

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Regulation of gene expression for translation initiation factor eIF-2 alpha: importance of the 3' untranslated region

Elena Urcelay

The Biochemical journal, 1996

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Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation

Scot Kimball

The Journal of nutrition, 2004

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Regulation of internal ribosome entry site-mediated translation by eukaryotic initiation factor-2α phosphorylation and translation of a small upstream open reading …

Maria Hatzoglou

Journal of Biological …, 2002

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Synthesis of the translational apparatus is regulated at the translational level

O. Meyuhas

European Journal of Biochemistry, 2000

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An Oncogenic Role for the Phosphorylated h-Subunit of Human Translation Initiation Factor eIF3

John Hershey

Journal of Biological Chemistry, 2008

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Leucine, Glutamine, and Tyrosine Reciprocally Modulate the Translation Initiation Factors eIF4F and eIF2B in Perfused Rat Liver

Jameel Shah

Journal of Biological Chemistry, 1999

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Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

Philippe P Roux

Proceedings of the National Academy of Sciences, 2008

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Dephosphorylation of the � Subunit of Eukaryotic Translation Initiation Factor 2

Shirish Shenolikar

2002

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mRNA Translation

Denis Feliers

Journal of the American Society of Nephrology, 2006

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Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

Olivia Novac

Proceedings of the National Academy of Sciences, 2005

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Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

HIren patel

Proceedings of the National Academy of Sciences, 1994

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Selection of the 5'-proximal translation initiation site is influenced by mRNA and eIF-2 concentrations

Richard Jackson

European Journal of Biochemistry, 1990

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Control of {alpha} subunit of eukaryotic translation initiation factor 2 (eIF2 {alpha}) …

seyedsobhan kazemi

… and Cellular Biology

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Inhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation

H. Fu, Xuerong Wang

Molecular and Cellular Biology, 2007

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The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans

Charles Samuel

Journal of Biological Chemistry, 1993

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All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5′-terminal oligopyrimidine (TOP) mRNAs

sara caldarola

RNA, 2008

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Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin

Aleksandar Sekulic

Science, 1997

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The eukaryotic translation initiation factor eIF4E wears a “cap” for many occasions

Katherine Borden

Translation, 2016

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Leucine-induced activation of translational initiation is partly regulated by the branched-chain α-keto acid dehydrogenase complex in C2C12 cells

Yoshinobu Ohira

Biochem Biophys Res Commun, 2006

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ERK1/2 map kinase metabolic pathway is responsible for phosphorylation of translation initiation factor eIF4E during in vitro maturation of pig oocytes

Michal Kubelka, A. Susor, Z. Ellederova

Molecular Reproduction and Development, 2008

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