Identification of Bacillus thuringiensis bacterial strain isolated from the mine soil as a robust agent in the biosynthesis of silver nanoparticles with strong antibacterial and anti-biofilm activities (original) (raw)

Biocatalysis and Agricultural Biotechnology

Abstract

Biofilm formation is one of the major problems associated with pathogenic bacteria besides drug resistance. In this study, the potential of the bacterial strain of mine soil in the biosynthesis of silver nanoparticles with antibacterial and anti-biofilm activities was investigated. The study revealed that the isolated Bacillus thuringiensis is an efficient bacterial strain in the biosynthesis of silver nanoparticles. Based on the results, the spherical biosynthesized silver nanoparticles with a 42 nm average size have good antibacterial properties at low concentrations (MIC = 6.25–12.5 μg/mL). Moreover, these nanoparticles not only inhibited the formation of biofilm, but were also able to interfere in biofilm metabolic activity and its degradation. Besides, with increasing concentrations of nanoparticles, degeneration of bacterial biofilm also increased so that the highest rate of bacterial biofilm degeneration (>90%) was observed at 6 μg/mL concentration.

Sadegh Khorrami hasn't uploaded this paper.

Let Sadegh know you want this paper to be uploaded.

Ask for this paper to be uploaded.