Reliability and validity of the German version of the Myositis Activities Profile (MAP) in patients with inflammatory myopathy (original) (raw)
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Clinical Rheumatology, 2014
Objective-The goals of this study were to assess the predictive value of chart abstracted American College of Rheumatology-Functional Status (ACR-FS) with patient reported ACR-FS, and to relate them with measures of muscle function in a single institution cohort of patients with idiopathic inflammatory myopathies (IIMs). Methods-Demographic and clinical data on 102 patients with IIMs regularly followed in the Rheumatology and Neurology Clinics at the University of Kentucky Medical Center between 2006 and 2012 were obtained through retrospective chart review. Clinical and functional status evaluation, muscle performance testing, and body composition measures were performed on a subset of 21 patients. ACR-FS were obtained both by chart abstraction and direct patient report. Spearman's correlations were used to examine the relationship of ACR-FS derived from chart abstraction with direct patient report, as well as the relationship of measures of physical function and body composition with ACR-FS. Results-ACR-FS derived from chart abstraction was significantly correlated with ACR-FS derived from direct patient report (ρ=0.78, p<0.001). ACR-FS derived from chart abstraction was also significantly correlated with patient reported physical function (ρ= −0.71, p<0.001) and physical activity (ρ=−0.58, p<0.05), manual muscle testing (ρ= −0.66, p<0.01
Arthritis & Rheumatism, 2006
Methods. Previously performed FI (n ؍ 287) were analyzed for internal redundancy and consistency, and ceiling and floor effects. Content was evaluated and a preliminary revised FI was developed. To evaluate the construct validity of the preliminary revised FI, it was compared with isokinetic measurements of muscular strength and endurance, the Myositis Activities Profile, disease impact on general wellbeing, and creatine phosphokinase levels. Minor adjustments were made and the revised FI was investigated for interrater reliability and intrarater reliability over a 1-week period. After this, some minor, additional adjustments were made leading to the final version, FI-2. Results. Five tasks were removed from the original FI due to ceiling effects. Performance pace and number of repetitions were modified for the remaining tasks. A moderate correlation (r s ؍ 0.58) was found between the shoulder flexion task of the preliminary revised FI and isokinetic measurements of shoulder flexion endurance. Intraclass correlation coefficient (ICC) for interrater reliability of the revised FI varied from 0.86 -0.99 with no systematic differences. ICC for intrarater reliability varied from 0.56 -0.99 with systematic differences (P < 0.05) between test and retest in 3 of the tasks. The sit-up task was excluded due to low intrarater reliability resulting in the final 7-item FI-2. There was a good correlation between tasks on the right and left side suggesting that the FI-2 could be performed unilaterally. Conclusion. The FI-2 is a valid and reliable outcome measure of impairment for patients with polymyositis or dermatomyositis. It is well tolerated and the unilateral FI-2 requires a maximum of 20 minutes to perform. Further evaluation of sensitivity to change and testing in healthy individuals needs to be conducted.
Reliability of the Adult Myopathy Assessment Tool in Individuals With Myositis
Arthritis Care and Research, 2015
Objective. The Adult Myopathy Assessment Tool (AMAT) is a 13-item performance-based battery developed to assess functional status and muscle endurance. The purpose of this study was to determine the intrarater and interrater reliability of the AMAT in adults with myositis. Methods. Nineteen raters (13 physical therapists and 6 physicians) scored videotaped recordings of patients with myositis performing the AMAT for a total of 114 tests and 1,482 item observations per session. Raters rescored the AMAT test and item observations during a followup session (mean ؎ SD 19 ؎ 6 days between scoring sessions). All raters completed a single, self-directed, electronic training module prior to the initial scoring session. Results. Intrarater and interrater reliability correlation coefficients were >0.94 for the AMAT functional subscale, endurance subscale, and total score (all P < 0.02 for H o , <0.75). All AMAT items had satisfactory intrarater agreement (kappa statistics with Fleiss-Cohen weights, with values w ؍ 0.57-1.00). Interrater agreement was acceptable for each AMAT item (؍ 0.56-0.89) except the sit up (؍ 0.16). The standard error of measurement and 95% confidence interval range for the AMAT total scores did not exceed 2 points across all observations (AMAT total score range 0-45). Conclusion. The AMAT is a reliable, domain-specific assessment of functional status and muscle endurance for adult subjects with myositis. Results of this study suggest that physicians and physical therapists may reliably score the AMAT following a single training session. The AMAT functional subscale, endurance subscale, and total score exhibit interrater and intrarater reliability suitable for clinical and research use.
2004
for the International Myositis and Clinical Studies Group (IMACS) y Objective. To devise new tools to assess activity and damage in patients with idiopathic myopathies (IIM). Methods. An international multidisciplinary consensus effort to standardize the conduct and reporting of the myositis clinical trials has been established. Two tools, known as the myositis intention to treat index (MITAX) and the myositis disease activity assessment visual analogue scale (MYOACT), have been developed to capture activity in patients with IIM. In addition, the myositis damage index (MDI) has been devised to assess the extent and severity of damage developing in different organs and systems. These measures have been reviewed by the myositis experts participating in the International Myositis Assessment and Clinical Studies (IMACS) group and have been found to have good face validity and to be comprehensive. The instruments were assessed in two real patient exercises involving patients with adult dermatomyositis and inclusion body myositis. Results. The reliability of MITAX, MYOACT and MDI, measured by the intraclass correlation coefficient among the physicians, and the inter-rater reliability, as assessed by variation in the physicians' rating of patients, was fair to good for most aspects of the tools. Reliability and inter-rater agreement improved at the second exercise after the participants had completed additional training. Conclusions. The MITAX, MYOACT and MDI tools, which are now undergoing validity testing, should enhance the consistency, comprehensiveness and reliability of disease activity and damage assessment in patients with myositis.
Disability in patients with idiopathic inflammatory myopathies
Archives of the Balkan Medical Union
L'invalidité chez les patients aux myopathies inflammatoires idiopathiques Introduction. Les myopathies inflammatoires idiopathiques (MII) sont un groupe hétérogène de troubles caractérisé par une faiblesse musculaire chronique, une faible endurance musculaire et des infiltrats de cellules inflammatoires dans les tissus musculaires, avec des lésions organiques et des conséquences multiples et invalidantes. Le but de l'étude était de déterminer le degré d'invalidité chez les patients atteints de myopathies inflammatoires idiopathiques selon l'échelle de Rankin dans une cohorte moldave. Méthodes. Nous avons effectué une étude transversale de décembre 2015 à décembre 2018, dans laquelle ont été inclus des patients avec des MII. Les données démographiques et cliniques ont été collectées à l'aide d'un questionnaire spécifique, indiquant notamment le statut d'emploi et la dose d'entretien de corticostéroïdes. Pour estimer le degré d'incapacité fonctionnelle et d'invalidité au moment de l'enquête, nous avons appliqué l'échelle de Rankin modifiée, avec des scores ABSTRACT Introduction. Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of disorders, characterized by chronic muscle weakness, low muscle endurance and by the presence of inflammatory cell infiltrates in muscle tissue, with organ damage and disability. The objective of the study was to determine the degree of disability in a Moldavian cohort of patients with idiopathic inflammatory myopathies, by Rankin's scale. Methods. We performed a cross-sectional study, from December 2015 to December 2018, in which were included patients with IIMs. Demographic and clinical data were collected using a special questionnaire, including employment status, upholding dose of corticosteroids. In order to estimate the degree of functional disability at the time of the research, we applied the modified Rankin's scale, with possible scores from 0-no disability to 5-totally dependent. Results. 65 IIMs patients were enrolled in the study. Male to female ratio was 1:3.3, the patients' mean age was 50.2±11.7 years, the mean disease duration 95.2±6.89 months. According to modified Rankin's
Development of the sporadic inclusion body myositis physical functioning assessment (sIFA)
Muscle & Nerve, 2016
INTRODUCTION: Sporadic inclusion body myositis (sIBM) is a progressive idiopathic inflammatory myopathy characterized by atrophy and weakness of proximal and distal muscle groups resulting in a loss of independence and the need for assistive devices and supportive care. To assess treatment benefit of new therapies, a patient-reported outcome measure of physical function was developed. METHODS: The tool was rigorously developed in accordance with the U.S. Food and Drug Administration (FDA) Patient Report Outcomes (PRO) Guidance. A single-visit, observational study was conducted. Standard qualitative analytical methods were employed to analyze interview data and generate questionnaire items. RESULTS: Twenty concept elicitation and 19 cognitive debriefing interviews were conducted, and 6 expert physicians were consulted. The tool consists of 11 items scored on a 0-10 numerical rating scale. Subjects completed the questionnaire utilizing either paper or electronic administration.
Muscle & nerve, 2016
To assess self-reported physical functioning in patients with sporadic inclusion body myositis (sIBM), the sIBM Physical Functioning Assessment (sIFA) was developed. This research establishes the validity, reliability, and responsiveness of the sIFA in patients with sIBM. Data from 3 small, noninterventional, observational studies were analyzed. Several measures of physical function were included to assess validity. Reliability (Cronbach alpha, test-retest intraclass correlations), construct validity (correlations, analyses of variance), and responsiveness (effect size estimates) were evaluated. Cronbach alphas (range=0.86-0.91) and test-retest reliability (0.91) were highly satisfactory. Correlations with other measures provided evidence of convergent validity. sIBM patients able to walk without assistive devices scored significantly better on the sIFA (means=36.0-47.05) than those who require power mobility or wheelchairs (means=54.9-71.5), demonstrating the discriminating ability...