Porphyromonas Gingivalis: Biofilm Formation, Antimicrobial Susceptibility of Isolates from Cases of Localized Aggressive Periodontitis (Lap) (original) (raw)

Background: No information is available on the antimicrobial sensitivity pattern and guidelines for oral antibiotic therapy for Yemeni patients for those with localized aggressive periodontitis (LAP) due to Porphyromonas gingivalis, a condition that often requires complementary antibiotic treatment. Aim: The primary aim of the current study was to examine the antibiotic patterns and the potential relationship between P. gingivalis biofilm formation and the incidence of antibiotic resistance of clinical isolates on a group of antibiotics commonly used in oral/systemic therapy. Subjects and Methods: The study included 30 clinically diagnosed patients, and 30 strains of P. gingivalis were isolated from them. Microbial sampling, isolation, and identification of bacteria were performed using culture methods appropriate to anaerobic species. Biofilm production was evaluated by the phenotypic method, that is, tissue culture methods (TCPM). Also; each isolate was tested against 12 antibiot...