Ethnobotanical and antibacterial potential of Salvadora persica l: A well known medicinal plant in Arab and Unani system of medicine (original) (raw)
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Thamar University Journal of Natural & Applied Sciences
Fresh samples of Salvadora persica were collected from Hudiadah province at 23/2/2011 . They include steams ,roots, and leaves . The ethanolic and aqueous extracts were prepared as w/v . (2.5, 5, 10 )% for three plants parts . The microbial samples were collected from privet dentists clinics in Thamar province by mouth swab and mouth washing methods . S. aureu s S. mutans, , and C. albicans were isolated and a pure cultures were prepared to each microbes for farther studies .The effect of different parts of plant showed high antimicrobial activity of root extract followed by stem and leaves extracts and the antimicrobial effecacy concern positively with concentration. The ethanol extract showed more antimicrobial activity than hot water extract.
American Journal of Plant Sciences, 2018
Many efforts have been devoted to studying the inhibitory effect of Salvadora persica (Miswak) on oral microorganisms. However, information regarding its antibacterial activity against other human pathogens is rare. Particularly, against Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The purpose of this piece of work was to evaluate the antioxidant power and in vitro antibacterial activities of Salvadora persica extract against the three bacterial clinical isolates mentioned above. Therefore, the action of Salvadora persica extract on the three germs, studied via the aromatograms method, has given an inhibition zone 20, 18 and 14 respectively on Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The methanol extract of Salvadora persica using Soxhlet has given an output of 19%. The antioxidant evaluation, which was performed using the DPPH (1,1-diphenyl-2-picryl-hydrazyl), free radical scavenging method, indicated that the methanol extract showed good antioxidant efficiency (IC50 = 15.47 mg/ml) compared to ascorbic acid with (IC50 = 0.097 mg/ml).
Journal of clinical and diagnostic research : JCDR, 2016
Twigs of Salvadora persica (Miswak) plant are being used as a means of oral hygiene since ages for brushing teeth. Though clinical research and trials have shown promising results on effectiveness of Miswak, but some reports are conflicting. To evaluate the antimicrobial activity of crude aqueous and alcoholic extracts of Salvadora persica (Miswak) against the common microbial pathogens causing dental caries and periodontitis. A prospective study of one year duration was conducted in Yenopoya dental and medical college, Mangalore. The twigs of Salvadora persica were collected and alcoholic and aqueous extracts were prepared using standard techniques. The antimicrobial properties of the extracts against common oral pathogens like Streptococcus mutans, Streptococcus mitis, Candida albicans, Lactobacillus acidophilus, Prevotella intermedia, & Peptostreptococcus were performed by agar well diffusion method and two fold broth dilution method. No significant results was obtained when wate...
Journal of Oral Biology and Craniofacial Research, 2014
Aims: The use of natural plant extracts in pharmacology, medicine and dental hygiene has found a growing interest in modern scientific research. Salvadora persica is a natural tree whose fibrous branches have been approved by the World Health Organization for oral hygiene. Periodontitis is a highly prevalent adult gingival disease that leads to bone destruction and connective tissue attachment loss. The aim of this research was assessment the antimicrobial activities of methanolic extract of Salvadora persica (miswak) on isolated strains from the oral fluid. Methods: In practical section, 50 female university students (21.4 AE 1 year) participated in the study. Based on examination by a periodontist, they were grouped into (Group I, n ¼ 21) and (Group II, n ¼ 29) i.e. with and without periodontitis respectively. Their un-stimulated saliva samples were obtained in sterile tubes. While three bacterial genera, Staphylococcus, Streptococcus and Lactobacillus were identified in all subjects, Enterococcus and Escherichia were only detected in Group I. Results: A statistically significant difference in colonization levels between the two groups was observed. The effect of methanolic extract of S. persica against oral bacterial strains isolated from saliva was investigated using agar disc diffusion and microdilution methods. Although methanolic extract of S. persica was effective on growth inhibition of all strains, it was significantly more effective on Gram positive bacteria than Gram negative ones. Conclusions: Effective substances present in S. persica extracts, exhibit a broad range of antibacterial activity and affect almost all bacterial species regardless of the Gram-staining nature.
The Antibacterial and Antioxidant Effect of Salvadora persica on Antibiotic Resistant Strains
American Journal of Plant Sciences, 2018
Many efforts have been devoted to studying the inhibitory effect of Salvadora persica (Miswak) on oral microorganisms. However, information regarding its antibacterial activity against other human pathogens is rare. Particularly, against Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The purpose of this piece of work was to evaluate the antioxidant power and in vitro antibacterial activities of Salvadora persica extract against the three bacterial clinical isolates mentioned above. Therefore, the action of Salvadora persica extract on the three germs, studied via the aromatograms method, has given an inhibition zone 20, 18 and 14 respectively on Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The methanol extract of Salvadora persica using Soxhlet has given an output of 19%. The antioxidant evaluation, which was performed using the DPPH (1,1-diphenyl-2-picryl-hydrazyl), free radical scavenging method, indicated that the methanol extract showed good antioxidant efficiency (IC50 = 15.47 mg/ml) compared to ascorbic acid with (IC50 = 0.097 mg/ml).
Malaysian Journal of Science Health & Technology, 2022
Salvadora persica is widely used in dental field to improve dental health and promote dental hygiene. Although sodium hypochlorite is highly recommended and regarded as the most effective irrigant in root canal treatment to eliminate bacteria, it can cause harm to patients manifested by severe pain, rapid swelling and also obstruct breathing airway. However, it is believed that the chemical composition of Salvadora persica helps to treat and act as an antibacterial agent in root canal therapy. This study aims to obtain the crude compound from Salvadora persica by using the freeze drying method and to compare the antibacterial activity of the Salvadora persica and sodium hypochlorite against Enterococcus faecalis in aerobic condition. Antibacterial activity results showed that 150 mg/ml of Salvadora persica give comparable effect with sodium hypochlorite against Enterococcus faecalis. It is believed that 60% of alcoholic Salvadora persica extraction is an effective antimicrobial agen...
Materials, 2022
This study aimed to test the biocompatibility and antibacterial properties of Salvadora persica (S. persica) extract, a natural product, as an intracanal medication in comparison with calcium hydroxide (Metapaste, META BIOMED, Cheongju, Korea). The pH values of both materials were tested. The biocompatibility of S. persica extract and Metapaste was determined using light microscopy and MTT assays. The antibacterial action was tested using the zone of bacterial inhibition on four common bacterial species. In addition, intracanal medication was administered using 68 extracted single-rooted teeth contaminated with Enterococcus faecalis (E. faecalis), and the percentage reduction in colony count (% RCC) at 1, 3, and 7 days was measured. The extension of activity for both materials was assessed using histological sections and scanning electron microscopy. S. persica was found to be acidic in nature. Both materials showed significantly lower cell viability than the positive control cells ...