Evaluation of clinical and radiological outcomes of mineral trioxide aggregate and calcium hydroxide as indirect pulp capping agents in the treatment of deep carious lesion of permanent teeth (original) (raw)

Evaluation of mineral trioxide aggregate and calcium hydroxide cement as pulp-capping agents in human teeth

Journal of …, 2008

This study evaluated the histomorphologic response of human dental pulps capped with mineral trioxide aggregate (MTA) and Ca(OH) 2 cement (CH). Pulp exposures were performed on the occlusal floor of 40 human permanent premolars. After that, the pulp was capped either with CH or MTA and restored with composite resin. After 30 and 60 days, teeth were extracted and processed for histologic exam and categorized in a histologic score system. The data were subjected to Kruskal-Wallis and Conover tests (␣ ϭ .05). All groups performed well in terms of hard tissue bridge formation, inflammatory response, and other pulpal findings. However, a lower response of CH30 was observed for the dentin bridge formation, when compared with MTA30 and MTA60 groups. Although the pulp healing with calcium hydroxide was slower than that of MTA, both materials were successful for pulp capping in human teeth. (J Endod 2008;34:1-6)

A randomized clinical trial on the use of medical Portland cement, MTA and calcium hydroxide in indirect pulp treatment

Clinical Oral Investigations, 2013

Objectives Studies on indirect pulp treatment (IPT) show varying success rates of 73 to 97 %. The necessity of reopening the cavity and the question of the optimal capping material is still under debate. The aim of this prospective in vivo study was to compare the clinical and microbiological outcomes of mineral trioxide aggregate (MTA), medical Portland cement, and calcium hydroxide on the dentin-pulp complex of permanent and primary teeth treated with two-step IPT. Materials and methods In 86 regular patients (51 % men; 49 % women; age 17.2 years ±13.8), one deep carious lesion each was treated with incomplete caries removal, randomly selected capping with either calcium hydroxide (n =31), medical Portland cement (29) or white MTA (26), and re-entry (6.3 months ±1.0). Clinical (color, humidity, and consistency of dentin) and microbiological (Lactobacilli/Mutans Strep. counts) parameters were recorded at the first and second treatment. Results The IPT had a high success rate of 90.3 % regardless of the material used (p =0.72). The arrested lesions showed consistently darker, dry, and therefore, sclerotic dentine (p <0.05) as well as a decrease in bacterial counts at re-entry (Lactobacilli p =0.01/Mutans Strep. p =0.07). Conclusions The findings of this study support the use of the IPT as a treatment for deep carious lesions preferably with nonresorbing materials such as MTA or medical Portland cement. Clinical relevance The findings of this study could promote the improvement of the IPT as a one-step treatment of deep carious lesions when the remaining demineralized dentin would be sealed with durable restorations.

Clinical evaluation of mineral trioxide aggregate and biodentine as direct pulp capping agents in carious teeth

Journal of Conservative Dentistry, 2017

Background: Root canal treatment has been a routine treatment option for carious exposure of the dental pulp. In the context of minimally invasive dentistry, direct pulp capping (DPC) procedure with a reliable biomaterial may be considered as an alternative provided the pulp status is favorable. Mineral trioxide aggregate (MTA), a bioactive cement with excellent sealing ability and biocompatibility is capable of regenerating relatively damaged pulp and formation of dentin bridge when used as DPC agent. Biodentine is comparatively a new biomaterial claimed to possess properties similar to MTA and is currently explored for vital pulp therapy procedures. Aim: The aim of the present study was to evaluate the clinical response of pulp-dentin complex after DPC with MTA and biodentine in carious teeth. Subjects and Methods: Twenty-four permanent molars with carious exposure having no signs and symptoms of irreversible pulpitis were selected and assigned to one of the two groups, Group I-MTA and Group II-biodentine. Patients were recalled at 3 weeks, 3 months, and 6 months for clinical and radiographic evaluation. Fisher's exact test was used along with Chi-square test for statistical analysis. Results: Over a period of 6 months, MTA and biodentine showed 91.7% and 83.3% success rate, respectively, based on the subjective symptoms, pulp sensibility tests, and radiographic appearance. Conclusion: MTA and biodentine may be used as DPC agents when the pulpal diagnosis is not more than reversible pulpitis.

Comparative Evaluation of Effectiveness of Calcium Hydroxide, MTA, and TheraCal LC in Indirect Pulp Capping in Primary Molars: In Vivo Study

˜The œjournal of contemporary dental practice, 2024

Aim: This investigation aimed to observe the effects of Dycal, mineral trioxide aggregate (MTA), and TheraCal LC, as indirect pulp-capping materials in primary molars. Materials and methods: About 75 children with lower primary molars aged between 4 and 7 years suggested for IPC were selected and randomly allocated into: Group I-Dycal, group II-MTA, and group III-TheraCal LC. An immediate postoperative radiograph was taken after the procedure. Recall examination was done after 3 and 6 months for clinical and radiographic assessment. The radiographs were digitized, and the amount of thickness of dentin was assessed using Corel Draw software. The values were tabulated and subjected to paired t-tests and independent t-tests for intra and intergroup analysis, respectively. The p-value < 0.05 was considered statistically significant. Results: There was a statistically significant increase in dentin thickness in the first 3 months compared to the 6-month follow-up. At the end of the research phase, TheraCal LC had more tertiary dentin deposited than MTA, followed by Dycal. Conclusion: TheraCal LC can be a reliable indirect pulp-capping agent in primary teeth. Clinical significance: Indirect pulp capping (IPC) is a very extensively employed treatment regimen to manage extensive caries. For many decades, calcium hydroxide has been regarded as the benchmark of pulp capping materials. With several advancements in materials for restoration, TheraCal LC a resin-modified, light-cured calcium silicate-filled liner serves as a pulp-capping agent and dentin protector, promoting pulp healing and preserving vitality as an obstacle cum protector of the dental pulp complex.

A Comparative Study between Mineral Trioxide Aggregate and Calcium Hydroxide as Pulp Capping Agents in Dog's Teeth

Dental research journal, 2008

Introduction: This study was carried out in order to compare mineral trioxide aggregate (MTA) and dycal in dog's teeth as pulp capping agents. Methods: After general and local anesthesia forty-two teeth of three dogs were used. In each tooth a class V cavity was prepared and the pulp was exposed using No.1 round bur. Then the exposed area was capped using either MTA or calcium hydroxide and the rest of the cavity was restored by amalgam. Radiographic image was taken before the procedure and after 4, 8 , and 12 weeks. The animals were sacrificed at 4, 8, and 12 weeks and the teeth were prepared for H&E staining. The pulps of the teeth were evaluated for inflammation, necrosis, and formation and thickness of calcified bridge. Histologic data were analyzed by Kruskal Wallis, ², Cochran, and Friedman tests. Results: Histopathologic results showed that in four weeks, MTA had significant differences with calcium hydroxide in the presence and thickness of calcified bridge (p=0.046) as well as inflammation (p= 0.014) and hyperemia (p=0.014). Eight weeks MTA specimens showed significant difference in thickness of calcified bridge (p=0.008). Twelve weeks after pulp capping, the amount of necrosis and chronic inflammation were higher in dycal specimens; however, there was no significant difference between two experimental groups. Radiographic evaluation did not show any periapical lesion, internal and external resorption, or widening of periodontal ligament in none of the teeth at all time intervals. Conclusion: Based on the result of this study, MTA showed to be a more reliable material as pulp capping agent in comparison with calcium hydroxide.

To Compare the Effectiveness of Biodentine versus Mineral Trioxide aggregate as Direct Pulp Capping agent in carious exposed permanent tooth

Pakistan Journal of Medical and Health Sciences

Aim: To compare the effectiveness of Biodentine versus mineral trioxide aggregate as direct pulp capping agent in carious exposed permanent tooth Study Design: Randomized controlled trial Placeand duration: Operative Dentistry, Department of de’Montmorency College of Dentistry / Punjab Dental Hospital, Lahore From 29-07-16 to 30-01-17 Methods: Sample size of 75 in each group (using non-probability) calculated using 80 percent power, 5% level of significance with expected percentage of effectiveness (lack of periapical radiolucency) among groups i.e. 92.68%19 in Biodentine group vs. 78%20 in mineral trioxide group aggregate as direct pulp capping agent. Data was entered and analyzed with IBM SPSS 20. Level of significance was kept at p-value ≤ 0.05. Results: Total 150 patients, 82 are male and 68 are female. The age of patients was 18-45 years. The Mean and SD of age of patients is 30±7.916. In group I, 57(75%) showed efficacy and 18(25%) showed failure of efficacy while in group II ...

Mineral Trioxide Aggregate (MTA) vs Calcium Hydroxide in Direct Pulp Capping -Literature Review

Iris Publishers LLC, 2018

Direct pulp-capping is a treatment for exposed vital pulp involving the placement of a dental material over the exposed area to facilitate both the formation of protective barrier and the maintenance of vital pulp. Direct pulp capping has been used as an alternative approach to the maintenance of vital pulp so that many tooth extractions and root canal treatments could have been avoided through the conservative approach of direct pulp capping. For this purpose different kinds of materials used such as Zinc Oxide Eugenol, Glass Ionomer (GI), Resin Modified Glass Ionomer (RMGI), Adhesive systems, Calcium Hydroxide, Mineral Trioxide Aggregate (MTA) and Bio dentine. The MTA clinically performed more effective than conventional Calcium Hydroxide liner as a direct pulp capping material, showed higher success rate than dycal. MTA easier to use clinically as a direct pulp capping material. MTA provided better long term results more effective than Calcium Hydroxide in maintaining long-term vitality. MAT significantly less toxic, less pulpal inflammations. MTA more predictable than dycal in formation of dentin barrier and superior than Calcium Hydroxide in dentinogenetic process in human pulp. MTA is more effective and superior comparing the Calcium Hydroxide as a direct pulp capping material, showed higher success rate with favorable outcomes in maintaining long term tooth vitality and easier to use in pulp capping. MTA is less toxic, less pulpal inflammation capping compared to Calcium Hydroxide. MTA superior and in dentinogenic process and more predictable hard tissue barrier formation.

MTA and calcium hydroxide for pulp capping

Journal of Applied Oral Science, 2005

This study evaluated the biocompatibility of mineral trioxide aggregate (MTA) after direct capping of exposed pulp tissue in dog's teeth. Class I cavities were prepared in 26 teeth from 3 adult dogs. MTA was applied over the exposed pulp in 13 teeth and paste of calcium hydroxide plus distilled water (control) was applied in the remaining 13 teeth. After 90 days, the animals were killed; the maxilla and mandible were dissected and sectioned to obtain individual roots. The samples were processed histologically. The pulp and periapical response observed with the use of MTA was similar to that of calcium hydroxide paste. In all specimens, there was a dentin bridge obliterating the exposure, an intact odontoblastic layer, no inflammatory cells, normal connective pulp tissue, normal apical and periapical regions and no bone tissue changes. Similar to calcium hydroxide, MTA presented excellent response when used for direct pulp capping.

Evaluation of two mineral trioxide aggregate compounds as pulp-capping agents in human teeth

International Endodontic Journal, 2009

Aim The present randomized, controlled prospective study evaluated the histomorphological response of human dental pulps capped with two grey mineral trioxide aggregate (MTA) compounds. Methodology Pulp exposures were performed on the occlusal floor of 40 human permanent pre-molars. The pulp was capped either with ProRoot (Dentsply) or MTA-Angelus (Angelus) and restored with zinc oxide eugenol cement. After 30 and 60 days, teeth were extracted and processed for histological examination and the effects on the pulp were scored. The data were subjected to Kruskal-Wallis and Conover tests (a = 0.05). Results In five out of the 40 teeth bacteria were present in pulp tissue. No significant difference was observed between the two materials (P > 0.05) in terms of overall histological features (hard tissue bridge, inflammatory response, giant cells and particles of capping materials). Overall, 94% and 88% of the specimens capped with MTA-Angelus and ProRoot, respectively, showed either total or partial hard tissue bridge formation (P > 0.05). Conclusions Both commercial materials ProRoot (Dentsply) and MTA-Angelus (Angelus) produced similar responses in the pulp when used for pulp capping in intact, caries-free teeth.