Screening an Archetypal Collection of Microorganisms for the Presence of Unexplored Antimicrobial Compounds (original) (raw)

Background WHO estimates that more than 700.000 people die every year as a result of drug-resistant infections. To tackle this problem and change the current trend, it is necessary to design advanced strategies for drug discovery and to promote early-stage research activities finalized at the development of new drugs (World Health Organization 2015). New information In this study, we present the results of the preliminary screening of a library of microorganisms, collected from different environmental settings. Approximately 300 strains of the culture collection were tested on solid medium for inhibition of growth of three tester ‡ ‡ ‡ § ‡ ‡