Oral Changes in Patients with Sickle Cell Anemia of Dentistry Interest (original) (raw)

Oral Findings in Sickle Cell Anemia Patient -A Case Report

Case Reports in Odontology, 2021

Sickle cell disease is an autosomal recessive disorder of blood with defective RBCs that assume sickle shape, have short lifespan leading to vascular occlusion that can affect any organ in the body. It can show a variety of oral manifestations affecting the soft tissues and teeth. Dental pulp could show aseptic necrosis without any trauma or caries or restoration of the involved tooth. In this case report, we present a case of dento-alveolar abscess formation of the left mandibular molar in a patient with sickle cell disease. It had a sudden onset, the involved molar had only enamel caries and the lesion subsided with a course of antibiotics. Our patient also had enamel hypomineralization of maxillary incisors.

Oral Health Status of Sickle Cell Anaemia Patients – A Case Control Study

IOSR Journals , 2019

Objective: To evaluate the oral hygiene status of Sickle cell anaemia (SCA) patients and control group using Oral Hygiene Index Simplified (OHI-S), Decayed Missing Filled Tooth (DMFT) index and Decayed Missing Filling Surface (DMFS) index. To compare oral hygiene status of SCA patients with control group. To counsel and educate SCA patients, control group children and their parents/guardians. Material and Method: Descriptive survey was conducted A total of 86 patients were included in SCA group and 88 in control group. DMFT and OHIS was recorded. Result: A significant difference in DMFT and DMFS indices was found between SCA and control group (p<0.01 and p<0.001) respectively. The OHI-S of SCA and control group was similar. No Significant difference was there in mean DMFT, DMFS & OHI-S scores with respect to sex and age in AS pattern of SCA. Significant difference was only found in mean DMFT score in age group of SS pattern. 5-10 (3.5000) age group is having significantly more caries rate when compared with 11-15(1.3333) and 16-20(1.8000) age group (p=0.02). Conclusion: SCA patients are more prone to caries than control group. Severity of the disease does not affect the prevalence of dental caries.

Dental Complications of Sickle Cell Disease

JBR Journal of Interdisciplinary Medicine and Dental Science, 2014

Sickle cell is a complex inherited molecular disorder of hemoglobin structure. Recurrent painful vaso-occlusive crises are its hallmark. In addition, it is associated with chronic hemolytic anemia and its consequences that often require blood transfusion. Moreover, infection and progressive organ and tissue damage result in several morbidities and increased mortality. Almost all body organs and tissues are affected including the nervous, cardiopulmonary, hepatobiliary, gastrointestinal, musculoskeletal, genitourinary, endocrine and dermatologic systems. Although most of these systems are relatively well described and studied, a few other systems have been neglected. Most common among these is the otolaryngological and dental systems despite the fact that patients and providers are aware that dental problems among patients with sickle cell disease are common and are often associated with other complications of the disease. This review describes the known dental complications of sickle cell disease with the hope that it may generate more studies and clinical trials on this neglected aspect of sickle cell disease.

Orofacial Manifestation and Dental Management of Sickle Cell Disease: A Scoping Review

Anemia

Aims. Sickle cell disease (SCD) is an upcoming global health problem with rapid progress in therapy especially since 2017. However, systematic reviews found no clinical trials on the dental treatment of sickle cell disease (SCD). This article aims to outline the oral features of the sickle disease and discuss oral management strategies that can serve as guidelines for dental professionals. Material and Methods. A comprehensive literature review was conducted using PubMed, Google Scholar, and Web of Science. The search strategies were developed to cover publications from January 2010 to March 2020. With the help of keywords, multiple abstracts were identified. These abstracts were further reviewed, which included the information about the SCD manifestation, particularly about the oral health features. Based on all these articles and clinical experience, a narrative review was constructed, which summarizes all the aspects of the oral manifestation in people with SCD. Results. The resu...

Oral considerations in the management of sickle cell disease: a case report

Oral health and dental management, 2012

The phenomenon of erythrocyte sickling observed in sickle cell anaemia is responsible for ischaemia and tissue infarction compromising several organs and systems including the mouth and face. This brief paper reports the case of a 17- year-old female with a complicated sickle cell anaemia, hypertension and paraplegia (after an ischaemic stroke at the age of six years). Oral examination revealed the absence of tooth 12, fractures of teeth 11, 21 and 22 (from trauma), active caries lesions in the enamel of teeth 36, 37 and 46, mucosal pallor, and a smooth tongue. Oral radiographs revealed bone rarefaction and trabecular bone coarsening. Dental surgeons and physicians should be aware of the general and oral abnormalities that can be present in individuals with sickle cell anaemia to allow for preventive measures and implementation of effective treatment options.

Treatment of dental complications in sickle cell disease

Protocols, 1996

Background Sickle cell disease is the most common single gene disorder and the commonest haemoglobinopathy found with high prevalence in many populations across the world. Management of dental complications in people with sickle cell disease requires special consideration for three main reasons. Firstly, dental and oral tissues are affected by the blood disorder resulting in several oro-facial abnormalities. Secondly, living with a haemoglobinopathy and coping with its associated serious consequences may result in individuals neglecting their oral health care. Finally, the treatment of these oral complications must be adapted to the systemic condition and special needs of these individuals, in order not to exacerbate or deteriorate their general health. Guidelines for the treatment of dental complications in this population who require special care are unclear and even unavailable in many aspects. Hence this review was undertaken to provide a basis for clinical care by investigating and analysing the existing evidence in the literature for the treatment of dental complications in people with sickle cell disease. Objectives To assess methods of treating dental complications in people with sickle cell disease. Search methods We searched the Cochrane Haemoglobinopathies Trials Register, compiled from electronic database searches and handsearching of journals and conference abstract books.

Is sickle cell anemia a risk factor for severe dental malocclusion?

Brazilian Oral Research, 2015

The aim of this study was to investigate possible associations between sickle cell anemia (SCA) and the severity of dental malocclusion (MO). This was a retrospective cohort study of 93 individuals with SCA (G1) and 186 individuals without the disease (G2). SCA patients were randomly selected by a simple draw from patients treated in the Centro de Hematologia e Hemoterapia do Maranhão (HEMOMAR) in northeastern Brazil. Patients aged between 16 and 60 were included after being tested for the hemoglobin S gene. G2 consisted of individuals living in the same residence as the patients. The Dental Aesthetic Index (DAI), as well as some morphological deviations not included in DAI, were used for the orthodontic evaluation of MO. Poisson regression with robust variance adjustment was employed to estimate relative risk (RR). In the multivariate analysis, SCA was associated with moderate (RR = 1.36) and very severe MO (RR = 8.0). SCA is correlated with anterior tooth loss (RR = 1.94), anterior spacing (RR = 1.66), overjet (RR = 1.87), anterior crossbite (RR = 1.94), and open bite (RR = 1.94). Thus, SCA is a risk factor for moderate and very severe MO.

Oral Rehabilitation of Patient with Sickle Cell Anemia and Dental Anomaly: Case Report

Egyptian Dental Journal, 2017

Sickle cell anemia patients with dental anomalies represent a difficult challenge for the prosthetic dentist. Proper treatment planning with the medical and dental management of these patients are important prerequisites for successful results. This case report describes a full-mouth rehabilitation of a sickle cell anemia patient with worn-down dentition including the treatment planning, medical consultation, correction of vertical dimensions of occlusion, preparation, and restoration with porcelain fused to metal crowns.

Sickle cell disease and dental treatment

Journal of the Irish Dental Association

Sickle cell disease (SCD) and sickle cell trait (SCT) are found most frequently in individuals of African, Middle Eastern and Indian ethnicity. Population migration has made this disease more common worldwide, including Ireland. We present an overview of this disease, focusing on management and practical implications for dental practitioners.