Astrocytes Couple Synaptic Activity to Glucose Utilization in the Brain (original) (raw)

Role of astrocytes in coupling synaptic activity to glucose utilization

Luc Pellerin

International Congress Series, 2002

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Cellular Mechanisms of Brain Energy Metabolism. Relevance to Functional Brain Imaging and to Neurodegenerative Disordersa

Luc Pellerin

Annals of the New York Academy of Sciences, 1996

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Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex

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Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy

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The Journal of neuroscience, 2003

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Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

Luc Pellerin

Proceedings of the National Academy of Sciences, 1994

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Cellular Bases of Brain Energy Metabolism and Their Relevance to Functional Brain Imaging: Evidence for a Prominent Role of Astrocytes

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CrossTalk opposing view: lack of evidence supporting an astrocyte-to-neuron lactate shuttle coupling neuronal activity to glucose utilisation in the brain

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Glucose Tightly Controls Morphological and Functional Properties of Astrocytes

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Higher Transport and Metabolism of Glucose in Astrocytes Compared with Neurons: A Multiphoton Study of Hippocampal and Cerebellar Tissue Slices

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Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle

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Changes in cytosolic glucose level in ATP stimulated live astrocytes

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Regional glucose metabolism and glutamatergic neurotransmission in rat brain in vivo

Anant Bahadur Patel

2004

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GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission

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Proceedings of the National Academy of Sciences, 2003

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[(18)F]FDG PET signal is driven by astroglial glutamate transport

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Why glucose transport in the brain matters for PET

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Trends in Neurosciences, 2005

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Activity-dependent regulation of energy metabolism by astrocytes: An update

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Glutamate mediates acute glucose transport inhibition in hippocampal neurons

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Astrocytes as metabolic suppliers to support neuronal activity and brain functions

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Positron emission tomography imaging of regional cerebral glucose metabolism

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How Astrocytes Feed Hungry Neurons

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In vivo synaptic density relates to glucose metabolism at rest in healthy subjects, but is strongly modulated by regional differences

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Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes

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Stability of regional cerebral glucose metabolism in the normal brain measured by positron emission tomography

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Neighborly interactions of metabolically-activated astrocytes in vivo

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Neuroenergetics: Astrocytes Have a Sweet Spot for Glucose

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Effects of fluctuating glucose concentrations on oxidative metabolism of glucose in cultured neurons and astroglia

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Glucose deprivation depolarizes plasma membrane of cultured astrocytes and collapses transmembrane potassium and glutamate gradients

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Brain metabolic sensing and metabolic signaling at the level of an astrocyte

Anna Hadjihambi

Glia, 2017

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Neuronal–glial glucose oxidation and glutamatergic–GABAergic function

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Frontiers in cellular neuroscience, 2013

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Astroglial Contribution to Brain Energy Metabolism in Humans Revealed by 13C Nuclear Magnetic Resonance Spectroscopy: Elucidation of the Dominant Pathway for Neurotransmitter Glutamate Repletion and Measurement of Astrocytic Oxidative Metabolism

Kevin Behar

2000

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