Structural Basis For HIV-1 DNA Integration in the Human Genome (original) (raw)
Human immunodeficiency virus integration complexes are active following ordered addition of wild type integrase, viral DNA, and LEDGF/p75
Jacob Russo
View PDFchevron_right
An Unusual Helix Turn Helix Motif in the Catalytic Core of HIV-1 Integrase Binds Viral DNA and LEDGF
Richard Maroun
PLoS ONE, 2009
View PDFchevron_right
X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293) - an initial glance of the viral DNA binding platform
Joan Zugay-Murphy, Vinod Sardana
Journal of Molecular Biology, 2000
View PDFchevron_right
Structural and Functional Role of INI1 and LEDGF in the HIV-1 Preintegration Complex
Marc Ruff
PLoS ONE, 2013
View PDFchevron_right
Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes
Ryan Reinke
The EMBO Journal, 2001
View PDFchevron_right
Major and Minor Groove Contacts in Retroviral Integrase−LTR Interactions
Colleen Jonsson
Biochemistry, 1999
View PDFchevron_right
Integrase and integration: biochemical activities of HIV-1 integrase
Dinu Eric
…, 2008
View PDFchevron_right
Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry
susana vioque rocha
Scientific Reports, 2016
View PDFchevron_right
DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2
D. Van Gent
Nucleic Acids Research, 1991
View PDFchevron_right
Oligomerization within Virions and Subcellular Localization of Human Immunodeficiency Virus Type 1 Integrase
Caroline Petit
1999
View PDFchevron_right
HIV-1 Integrase and Virus and Cell DNAs: Complex Formation and Perturbation by Inhibitors of Integration
Richard Maroun
Neurochemical Research, 2010
View PDFchevron_right
HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells
Goedele Maertens
Journal of Biological Chemistry, 2002
View PDFchevron_right
Integrase-LEDGF/p75 complex triggers the formation of biomolecular condensates that modulate HIV-1 integration efficiency in vitro
Julien Batisse, Claire Batisse
View PDFchevron_right
Integrase Mutants Defective for Interaction with LEDGF/p75 Are Impairedin Chromosome Tethering and HIV-1Replication
Catherine Dargemont
Journal of Biological Chemistry, 2005
View PDFchevron_right
Cellular co-factors of HIV-1 integration
Linos Vandekerckhove
Trends in Biochemical Sciences, 2006
View PDFchevron_right
Quantitative analysis of HIV-1 preintegration complexes
ilker öztop
Methods, 2009
View PDFchevron_right
HIV-1 integrase and virus and cell DNAs: complex formation and perturbation by inhibitors of integration. Neurochem Res 35: 888–893
Zeina Hobaika
2010
View PDFchevron_right
Integrase mutants of human immunodeficiency virus type 1 with a specific defect in integration
Chris Farnet
Journal of Virology, 1994
View PDFchevron_right
Interaction between HIV-1 Rev and Integrase Proteins: A BASIS FOR THE DEVELOPMENT OF ANTI-HIV PEPTIDES
Amnon Hizi
Journal of Biological Chemistry, 2007
View PDFchevron_right
Defining the DNA Substrate Binding Sites on HIV-1 Integrase
Irene Weber
Journal of Molecular Biology, 2009
View PDFchevron_right
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
Goedele Maertens
Nature Structural & Molecular Biology, 2005
View PDFchevron_right
HIV-1 cDNA Integration: Requirement of HMG I(Y) Protein for Function of Preintegration Complexes In Vitro
Chris Farnet
Cell, 1997
View PDFchevron_right
Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding
Larry Miercke
Proceedings of the National Academy of Sciences, 2000
View PDFchevron_right
Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
Mark Andrake
PLoS ONE, 2011
View PDFchevron_right
The Human Polycomb Group EED Protein Interacts with the Integrase of Human Immunodeficiency Virus Type 1
Sébastien VIOLOT
Journal of Virology, 2003
View PDFchevron_right
Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding
Goedele Maertens
Nucleic Acids Research, 2014
View PDFchevron_right
A Three-dimensional Model of the Human Immunodeficiency Virus Type 1 Integration Complex
Jerome Wielens
Journal of Computer-Aided Molecular Design, 2005
View PDFchevron_right
Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition
Chris Farnet
Journal of virology, 1997
View PDFchevron_right
Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase
Xiaojian Yao
Virology Journal, 2010
View PDFchevron_right
Genetic Analyses of DNA-Binding Mutants in the Catalytic Core Domain of Human Immunodeficiency Virus Type 1 Integrase
Hina Ghory
Journal of Virology, 2005
View PDFchevron_right
Identification of the LEDGF/p75 Binding Site in HIV-1 Integrase
Marc De Maeyer
Journal of Molecular Biology, 2007
View PDFchevron_right
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
Paul Kellam
Genes & Development, 2007
View PDFchevron_right