Extending platelet storage: safety and quality considerations (original) (raw)

2009, ISBT Science Series

AI-generated Abstract

This study discusses the limitations of current platelet storage practices, focusing on the phenomena of platelet storage lesion (PSL), which adversely affects the quality and function of stored platelets. It examines the factors influencing PSL, including storage duration, temperature, platelet concentration, and container characteristics. The implications for transfusion practices, particularly concerning bacterial contamination and platelet function, are addressed, with recommendations for extending storage times and improving transfusion safety and efficacy.