original ) (raw )Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen
Megan Sykes
Biology of Blood and Marrow Transplantation, 1999
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Immuno-intervention for the induction of transplantation tolerance through mixed chimerism
Megan Sykes
Seminars in Immunology, 2011
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Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation
Ayse Atasoylu
Blood, 1991
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Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and tolerance
Boris Nikolic
Transplant International, 2002
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Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning
John Mordes
Journal of Clinical Investigation, 2003
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Addition of Cyclophosphamide to T-cell Depletion–Based Nonmyeloablative Conditioning Allows Donor T-cell Engraftment and Clonal Deletion of Alloreactive Host T-cells After Bone Marrow Transplantation
Paula Chilton
Transplantation, 2007
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Immunological importance of chimerism in transplantation: new conditioning protocol in BMT and the development of chimeric state
K. Rajczy
Human Immunology, 2000
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Production of Donor T Cells Is Critical for Induction of Donor-Specific Tolerance and Maintenance of Chimerism
Paula Chilton
Journal of Immunology, 2004
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Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model
Michael Murphy
Journal of Clinical Investigation, 2000
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Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies
Pratik Multani
Biology of Blood and Marrow Transplantation, 2000
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Bone marrow chimerism and transplantation tolerance
Boris Nikolic
Current Opinion in Immunology, 1997
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Combined host-conditioning with CTLA4-Ig, tacrolimus, anti-lymphocyte serum, and low-dose radiation leads to stable mixed hematopoietic chimerism
Si Pham
Experimental Hematology, 2001
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Cutting Edge: Administration of Anti-CD40 Ligand and Donor Bone Marrow Leads to Hemopoietic Chimerism and Donor-Specific Tolerance Without Cytoreductive Conditioning
Christian Larsen
The Journal of Immunology, 2000
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Induction of classical transplantation tolerance in the adult
Stephen Cobbold
Journal of Experimental Medicine, 1989
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Effects of non-major histocompatibility antigens on acute graft-versus-host reaction after allogeneic bone marrow transplantation
Kazuya Iwabuchi
Bone Marrow Transplantation, 1997
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Immune Reconstitution Kinetics following Intentionally Induced Mixed Chimerism by Nonmyeloablative Transplantation
JungHoon Shin
PLOS ONE, 2015
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Induction of Permanent Mixed Chimerism and Skin Allograft Tolerance Across Fully MHC-Mismatched Barriers by the Additional Myelosuppressive Treatments in Mice Primed with Allogeneic Spleen Cells Followed by Cyclophosphamide
ichiro shimizu
The Journal of Immunology, 2000
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High-level allogeneic chimerism achieved by prenatal tolerance induction and postnatal nonmyeloablative bone marrow transplantation
Michael Hsieh
2002
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Mechanisms of Tolerance Induction by Hematopoietic Chimerism: The Immune Perspective
Haval Shirwan
STEM CELLS Translational Medicine
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Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: The importance of overcoming intrathymic alloresistance
Abrar N
Biology of Blood and Marrow Transplantation, 2001
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Anti-NK cell treatment induces stable mixed chimerism in MHC-mismatched, T cell-depleted, nonmyeloablative bone marrow transplantation
Satoshi Takahashi
Experimental Hematology, 2004
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Effects of Transient Donor Chimerism on Rejection of MHC-Mismatched Vascularized Composite Allografts in Swine
Curtis Cetrulo
Vascularized Composite Allotransplantation, 2015
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An MHC-Defined Primate Model Reveals Significant Rejection of Bone Marrow After Mixed Chimerism Induction Despite Full MHC Matching
A. Page
2010
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Induced regulatory T cells in allograft tolerance via transient mixed chimerism
Robert Colvin
JCI insight, 2016
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Allogeneic Hematopoietic Stem-Cell Transplantation, Mixed Chimerism, and Tolerance in Living Related Donor Renal Allograft Recipients
Varsha Trivedi
Transplantation Proceedings, 2005
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Chimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
Brenda Sandmaier
Leukemia, 2006
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Stable Mixed Hematopoietic Chimerism in Dogs Given Donor Antigen, CTLA4Ig, and 100 cGy Total Body Irradiation Before and Pharmacologic Immunosuppression After Marrow Transplant
Jan Maciej Zaucha
Blood, 1999
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Mixed chimerism induced without lethal conditioning prevents T cell– and anti-Galα1,3Gal–mediated graft rejection
Megan Sykes
Journal of Clinical Investigation, 1999
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Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning
Stephen Cobbold
BMC Immunology, 2006
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Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce durable complete chimerism and sustained remis...
Michael Maris
Blood, 2003
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Apoptotic Donor Leukocytes Limit Mixed-Chimerism Induced by CD40-CD154 Blockade in Allogeneic Bone Marrow Transplantation
Christian Larsen
Biology of Blood and Marrow Transplantation, 2006
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Chimerism and Tolerance Induction in Kidney Transplantation
Lorenzo Gallon
Nephron, 2015
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Donor-specific tolerance in a murine model: the result of extra-thymic T cell deletion?
Jose Vingerhoed
Transplant Immunology, 2003
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Immune monitoring of transplant patients in transient mixed chimerism tolerance trials
Megan Sykes
Human Immunology
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