Diagnosis and management of carotid body tumor: a report of seven cases (original) (raw)

Carotid body tumors: a case series and review of the literature

Annals of vascular surgery, 2017

Paragangliomas of the head and neck are rare vascular tumors derived from the paraganglia tissues originating from the neural crest. They are usually benign and hyper-vascularized. Diagnosis is relatively easy in condition to consider it in evaluating every lateral neck mass. We made a retrospective study of the records of ten patients who presented with carotid body tumors at the Vascular surgery department of the Military Hospital Avicenne in Marrakech during the period between 2008 and 2013. Epidemiologic, etiologic, diagnostic and therapeutic features were analyzed. The average age of our patients was 35,4 years (26 to 55 years), with a male predominance (sex-ratio: 2,33). We noted seven cases of isolated carotid locations and three cases of multiple locations. A slow growing neck mass was the main clinical presentation. Other signs were pain, dysphonia, dizziness, headache and tinnitus. Physical examination showed, in most cases, a neck nontender mass with side to side mobility...

Carotid body tumor: a case report and literature review

Journal of Radiology Case Reports, 2019

The carotid body is the largest collection of paraganglia in the head and neck and is found on the medial aspect of the carotid bifurcation bilaterally. Carotid body tumors are rare neoplasms arising from the chemoreceptor cells of the carotid bulb. We report a case of carotid body tumor in a 42year-old female, who presented with painless, pulsatile, gradually progressive lateral neck swelling. The diagnosis is suspected on the basis of history, clinical and radiological examination findings and a successful surgical excision of the tumor is performed. Histopathological examination confirms the diagnosis of carotid body tumor. We also present brief literature about carotid body tumors in terms of its clinical and imaging presentation, evaluation, and management. CASE REPORT Carotid body tumors (CBTs), also known as paragangliomas or chemodectomas, are rare neuroendocrine neoplasms which arise near the carotid bifurcation within glomus cells derived from the embryonic neural crest. The reported incidence of CBTs is 1-2 per 100,000 [1]. CBTs are rare chemical receptor tumors which accounts for 0.6% of the head and neck tumors in humans. The CBT is usually benign with the incidence of malignant tumors below 10% [2]. The majority of these tumors are asymptomatic and initially noticed by inspection and palpation of neck swelling during the physical examination, or more commonly as incidental findings on radiological imaging studies. Nonetheless, the most observed symptoms are a pain, dysphagia, and autonomic dysfunction in symptomatic cases [3], [4]. Clinical presentation of the tumor is an asymptomatic slow growing mass in neck. However, they can produce symptoms due to pressure and local invasion of the surrounding tissue. Most commonly involved are hypoglossal nerve, glossopharyngeal nerve, vagus nerve and sympathetic chain [5]. Clinical history, examination, and radiological diagnosis are the keystones to diagnosis and management. Ultrasound, Computed tomography (CT) and Magnetic resonance imaging (MRI) are useful radiological tools in diagnosis. Yet Angiography is essential to study about the vascular anatomy [6]. Thus, in order to prevent local invasion and metastasis, early surgical excision is considered a primer curative treatment option for the treatment of CBTs. In this paper, we report a case of CBT which was successfully treated with complete surgical excision and review the literature.

Carotid body tumor: retrospective analysis on 22 patients

Sao Paulo Medical Journal, 2014

CONTEXT AND OBJECTIVE: Carotid body tumors, or chemodectomas, are the most common head and neck paragangliomas, accounting for 80% of the cases. They may present minor symptoms; however, they deserve special attention in order to achieve accurate diagnosis and adequate treatment. The objectives of this study were to show the approach towards chemodectomas and evaluate the complications of the patients treated surgically without previous embolization.DESIGN AND SETTING: Retrospective study on chemodectomas followed up at the Head and Neck Surgery Service, Department of Surgery, Unicamp.METHODS: Twenty-two patients were evaluated between 1983 and 2009. The diagnosis was based on clinical findings and imaging methods. The epidemiological characteristics, lesion characteristics, diagnostic methods, treatment and complications were analyzed.RESULTS: The paragangliomas were classified as Shamblin I (9%), II (68.1%) and III (22.7%). Angiography, magnetic resonance imaging and computed tomo...

Clinical characteristics and remedies in 45 Iranians with carotid body tumors

Acta medica Iranica, 2012

Carotid body tumors (CBTs) are rare, slow-growing tumors that should be considered in evaluating every lateral neck mass. This single center study was performed to define demographic features, clinical characteristics and remedies of Iranian patients with CBT. A retrospective review of prospectively collected data was done on 45 patients with 50 CBTs who have been referred to Sina Hospital, Tehran, Iran, during a 10-year period, were investigated in this study. The demographic characteristics, clinical and pathologic features, imagings, preoperative treatments, surgical approach and complications were analyzed. The study group predominantly consisted of females (82%). Age of diagnosis was 18 to 75 years old. Five patients had bilateral CBT. Family history of CBT was positive in seven patients. Most of CBTs were ≤ 3cm in size. All of the patients presented with a neck mass, mostly without pain (84%). Other symptoms included vertigo 4%, dysphasia 4% and tinnitus 2%. There was no patie...

Diagnosis and surgical treatment of carotid body tumor: A report of 18 cases

Journal of Cardiovascular Disease Research, 2010

Objective: To summarize the experience in the diagnosis and treatment of carotid body tumor (CBT). Materials and Methods: CBT in 18 cases was confi rmed by digital subtraction angiography (DSA). Resection of the tumor under the carotid adventitial plane was performed in 10 cases, the tumor with the external carotid artery in fi ve cases, and the tumor with the internal and external arteries at the same time in three cases. Results: Neither death nor any major complications occurred in all the 18 cases. Our follow-up of the 18 patients revealed neither recurrence nor metastasis. Conclusion: DSA is the gold standard for the diagnosis of CBT. After confi rmation, thorough preoperative examination, suffi cient preoperative preparation, and correct surgical approaches can result in satisfactory surgical effects.

Carotid body tumors: challenging complexity of diagnosis and surgical treatment

Kulak Burun Bogaz Ihtisas Dergisi Kbb Journal of Ear Nose and Throat, 2003

Objectives: To evaluate the patients treated for carotid body tumors and the problems encountered during diagnosis and treatment. P a t i ents and Methods: The study included eight patients (5 females, 3 males; mean age 50 years; range 36 to 68 years) who underwent surgery for carotid body tumors. Diagnosis was confirmed by power Doppler ultrasonography and computed tomography or magnetic resonance imaging in all patients. Angiography was performed in three patients to evaluate vascularity and to perform embolization before surgery. Two patients had previously undergone biopsy elsewhere. The mean follow-up was 15 months (range 2 to 36 months). Res u l t s : The size of the tumors varied from 3 cm to 11 cm. In two patients the tumors were found to extend to the skull base. Ligation of the external carotid artery and the common carotid artery was performed in five patients and in one patient, respectively. Surgery-associated injuries given to the internal carotid artery in two patients were repaired by sutures. The 10th cranial nerve was dissected in two patients who had undergone a prior biopsy. They developed cord paralysis and hoarseness postoperatively. Resection of the 11th cranial nerve in one patient resulted in shoulder pain and drop shoulder. The 12th cranial nerve was repaired end-toend by neurorrhaphy in two patients. They exhibited significant improvement in nerve functions a year after surgery. Conclusion: The larger the tumor is, the more difficult the resection is, and the more injuries are caused to the surrounding nerves and vessels.

“Carotid body tumour: A case report”

IOSR Journal of Pharmacy and Biological Sciences, 2014

Carotid body tumours are rare, slowly growing benign neoplasm arising from paraganglionic cells at the region of carotid bifurcation. They are the rare tumours of head and neck region derived from neural crest. We report here a case of carotid body tumour which was successfully treated surgically.

Carotid Body Tumor - A Case Reports

University Heart Journal, 2012

Carotid body tumor, an extra-adrenal paraganglioma, represents an uncommon entity arising in chemoreceptor tissue located at the carotid bifurcation. They commonly present as asymptomatic neck masses and careful preoperative evaluation is required to find out the functional and vascular status of these tumours. An unusual case of a large (70 × 50 × 45 mm) carotid body tumor of Shamblin type III in a 50 year old male is being presented here. The evaluation, management and the final outcome of this case of carotid body tumour is being reported here. DOI: http://dx.doi.org/10.3329/uhj.v8i1.11670 University Heart Journal Vol. 8, No. 1, January 2012

Carotid body tumors: a subject review and suggested surgical approach

Journal of Neurosurgery, 1986

✓ Carotid body tumors are a rare but potentially difficult surgical entity. Their pathology, physiology, and natural history are reviewed along with surgical results reported in the literature. A surgical approach for removal of these tumors is presented which differs significantly from the recommended techniques in that emphasis is placed on intraoperative monitoring of cerebral blood flow, the selective use of shunts, a tumor-adventitial plane of dissection, preservation of the carotid artery complex, and mobilization of the parotid gland. Thirteen cases using these techniques are reviewed. The mortality rate and the incidence of cerebrovascular sequelae were both 0%. The major morbidity consisted of injury to the lower cranial nerves in five patients (39%) with tumors larger than 5 cm in length.