Respiratory virus infections (original) (raw)
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Respiratory Viruses; Today’s Troubled Agents, Candidates for Marker of Diagnosis and Prognosis
Indian Journal of Applied Research, 2011
Objective: The aim was to describe the clinical and epidemiologic characteristics of patients with lower respiratory tract infection (LRTI) who were hospitalized to the Pediatric Infection Department in Istanbul due to respiratory viruses from October 2010 through May 2011. Material and Methods: Details of the 156 patients who were hospitalized were recorded. Respiratory viruses were confirmed in specimens using real-time reverse transcriptase-polymerase-chain-reaction (RT PCR) assay. Results: Respiratory agents were detected in 48 (30.8%) of 156 children with LRTI. Fifty seven patients (36.5%) were female, 99 (63.5%) were male and the median age was 28.2 ±42.1 months. A single agent was identified in 41 (% 85) children, and multiple agents in 7 (%15). Influenza virus was the most common pathogen (31.2%), followed by rinovirus (20.8%), bocavirus (14.5%),coronavirus (10.4%), parainfluenza virus (8.3%), metapneumovirus (8.3%) and respiratory syncytial virus (6.2%).
Respiratory Tract Viral Infections
Elsevier eBooks, 2003
ADV, adenovirus; Flu, influenza virus; HRV, human rhinovirus; PIV, parainfluenza virus; RSV, respiratory syncytial virus. *Viruses were detected by isolation in cell culture or by antigen detection with immunofluorescence. Serology for some viruses was used in addition to viral isolation.
Revista română de boli infecţioase, 2023
In the period 2020-2022 as a result of epidemiological measures specific to the COVID-19 pandemic (protective mask, online teaching activity, social distancing) we witnessed a considerable decrease in the number of cases of respiratory viroids in children. With the lifting of prophylactic measures that coincided with the start of physical teaching activities and the onset of the cold season, we have been confronted in pediatric wards with an increase in the incidence of virological infections in the pediatric population. In this article we aim to analyze the particularities of respiratory virological diseases in children in the season 2022-2023 both from the etiological and epidemiological point of view and the characteristic clinical forms of the disease. We conducted a retrospective clinical study of cases admitted to the Clinical Departments of Infectious Diseases-Pediatrics of the National Institute of Infectious Diseases "Prof. Dr. Matei Bals" in the period October 2022-March 2023. During this period, we recorded 3.012 cases of respiratory virology in children, which represents the majority of pediatric pathology admitted (72,9 %). The peak incidence of respiratory virology occurred in December (688 cases). From the etiological point of view, most cases were SARS-CoV-2 infections, followed by influenza (predominantly type A), then a smaller number of infections with respiratory syncytial virus (RSV), rhinovirus, adenovirus, metapneumovirus. The most common clinical form of the disease was moderate (66.9%), with severe forms accounting for 10.5%. All pediatric cases of respiratory virology admitted to our wards have evolved favorably, with no deaths.
Viral Coinfection in Childhood Respiratory Tract Infections
2014
Introduction: The introduction of molecular techniques has enabled better understanding of the etiology of respiratory tract infections in children. The objective of the study was to analyze viral coinfection and its relationship to clinical severity. Methods: Hospitalized pediatric patients with a clinical diagnosis of respiratory infection were studied during the period between 2009 and 2010. Clinical and epidemiological data, duration of hospitalization, need for oxygen therapy, bacterial coinfection and need for mechanical ventilation were collected. Etiology was studied by multiplex PCR and low-density microarrays for 19 viruses. Results: A total of 385 patients were positive, 44.94% under 12 months. The most frequently detected viruses were RSV-B: 139, rhinovirus: 114, RSV-A: 111, influenza A H1N1-2009: 93 and bocavirus: 77. Coinfection was detected in 61.81%, 36.36% with two viruses, 16.10% and 9.35% with three to four or more. Coinfection was higher in 2009 with 69.79 vs 53.88% in 2010. Rhinovirus/RSV-B on 10 times and RSV-A/RSV-B on five times were the most detected coinfections. Hospitalization decreased with greater number of viruses (P<.001). Oxygen therapy was required by 26.75% (one virus was detected in 55.34% of cases). A larger number of viruses resulted in less need for oxygen (P<.001). Ten cases required mechanical ventilation, four patients with bacterial coinfection and five with viral coinfection (P=.69). Conclusions: An inverse relationship was found between the number of viruses detected in nasopharyngeal aspirate, the need for oxygen therapy and hospitalization days. More epidemiological studies and improved quantitative detection techniques are needed to define the role of viral coinfections in respiratory disease and its correlation with the clinical severity.
Respiratory Infections by virus: a review properties
Journal of Immunology Research & Reports
The understanding of the causes and risk factors of respiratory diseases can go to the early treatments and prevention of the complications that are so prevalent in these pathologies. There are a variety of types of respiratory virus that are capable of respiratory disease begin. Rhinovirus, influenza, respiratory syncytial virus (RSV), adenovirus and coronavirus are capable of beginning of a common influenza to pneumonia, bronchitis and asthma. One of the important questions in the actual days is to relation the respiratory viral infection with the bronchial hyperresponsiveness? The mechanisms that cause sibilance, the relation between autonomic nervous system and viral infection, the association virus and respiratory diseases and the treatment there is in nowadays are relevant matters. In this work it was pretend to explore explanations about these themes in the scientific literature
Virology Journal, 2012
Acute respiratory infections are a major cause of morbidity in children both in developed and developing countries. A wide range of respiratory viruses, including respiratory syncytial virus (RSV), influenza A and B viruses, parainfluenza viruses (PIVs), adenovirus, rhinovirus (HRV), have repeatedly been detected in acute lower respiratory tract infections (LRTI) in children in the past decades. However, in the last ten years thanks to progress in molecular technologies, newly discovered viruses have been identified including human Metapneumovirus (hMPV), coronaviruses NL63 (HcoV-NL63) and HKU1 (HcoV-HKU1), human Bocavirus (HBoV), new enterovirus (HEV), parechovirus (HpeV) and rhinovirus (HRV) strains, polyomaviruses WU (WUPyV) and KI (KIPyV) and the pandemic H1N1v influenza A virus. These discoveries have heavily modified previous knowledge on respiratory infections mainly highlighting that pediatric population is exposed to a variety of viruses with similar seasonal patterns. In t...