Solitary fibrous tumor of the parapharyngeal space: MR imaging findings (original) (raw)
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Solitary fibrous tumor of the parapharyngeal space
Ear, nose, & throat journal, 2007
Solitary fibrous tumors are benign neoplasms of mesenchymal origin. They usually arise from the visceral or parietal pleura and peritoneum, although they have been found in many areas throughout the body. We report a case of solitary fibrous tumor of the parapharyngeal space. Microscopically, the tumor contained spindle cells with areas of marked hypercellularity without a definitepattern. Consistent with a benign lesion, there were few mitoses and no necrosis. The tumor cells stained strongly positive for CD34 and vimentin. At the 2-year follow-up, the patient was well and free of local and/or distant disease.
Extensive solitary fibrous tumor of the retropharyngeal space
Head & Neck, 2006
Background. Solitary fibrous tumor (SFT) is a rare neoplasm whose histologic diagnosis poses significant problems in differential diagnosis. Although most of these neoplasms arise at the level of the pleura, there have also been reports of extrapleural origins. The most frequent localization in the head and neck region is in the nasal cavity.
Solitary Fibrous Tumor of the Larynx
Otolaryngology-head and Neck Surgery, 2005
Background True mesenchymal, non-cartilaginous neoplasms of the larynx are rare. Extrapleural solitary fibrous tumor (SFT) is a localized neoplasm characterized by proliferation of thin-walled vessels and collagen-producing cells and is considered within the ''hemangiopericytoma-solitary fibrous tumor'' spectrum. SFT primary in the larynx is exceptional. Design Case report set in a comparison with other cases reported in the English literature (MEDLINE 1966(MEDLINE to 2007. Results A 49year old white male presented with difficulty breathing, progressive over the past 2 years. He denied dysphagia and weight loss. Past medical history was significant for asthma. He denied cigarette smoking or alcohol abuse. There were no cervical deformities on physical exam. Fiberoptic laryngoscopy was performed upon stabilization of respiratory function. A smooth, round, submucosal mass measuring 2.3 cm in greatest diameter arising from the inferior surface of left true vocal cord was causing near total obstruction of the endolaryngeal space. The mass was excised. The surface mucosa was intact and unremarkable. A cellular, spindle cell neoplasm was arranged in loose fascicles, associated with heavy collagen fiber deposition. The collagen was wiry and heavy. Cells were bland with cytoplasmic extensions. The nuclei were vesicular to hyperchromatic and elongated with inconspicuous nucleoli. Vessels were prominent and delicate, with patulous spaces. Mitotic figures were easily identified, but atypical forms were not present. The cells were strongly and diffusely immunoreactive with CD34 and bcl-2, while non-reactive with cytokeratin, EMA, actin, ALK-1, S100, desmin, and CD117. These findings confirmed a diagnosis of extraplural solitary fibrous tumor. Without further disease, the patient is alive without evidence of disease, 12 months after surgery. Conclusions The characteristic histologic pattern of solitary fibrous tumor can be noted in extrapulmonary locations. Development in the larynx is uncommon, but the tumor presents as a polypoid mass with characteristic histologic and immunophenotypic features. Conservative local excision is the treatment of choice to yield an excellent prognosis.
Solitary fibrous tumor of the larynx: Literature review and a case presentation
Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2016
Introduction: Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, which is traditionally seen as a pleural mass, but can also occur in other locations. Although SFTs are very rare in the head and neck region, they have been reported in the orbit, nasal cavity, paranasal sinus, nasopharynx, parapharyngeal space, thyroid gland, and larynx. Laryngeal involvement has been previously reported in only 11 cases. Case report: The case is here presented of a 57-year-old male with complaints of progressive hoarseness and difficulty in breathing which had been ongoing for 1 year. By direct laryngoscopy the mass which was oriented from the right vocal cord was totally excised. Discussion: The clinical, radiological and histopathological findings are reported here, with a review of literature, to comprise the twelfth case of laryngeal solitary fibrous tumor.
Solitary fibrous tumor of the larynx: report of two new cases
Jornal Brasileiro de Patologia e Medicina Laboratorial, 2014
Solitary fibrous tumor is a rare neoplasm. Few cases have been described in the head and neck area, and less than 11 were located in the larynx. We described two new cases of solitary fibrous tumor of the larynx. A man, 64-year-old, and a woman, 77-year-old, both with submucosal and nodular supraglottic lesions, were submitted to surgical treatment and both showed CD-34 and bcl-2 immunoreactivity and S-100 and smooth-muscle actin negativity. After 24 and 22 months of postoperative follow-up, respectively, they did not show signs of active disease.
Role of MRI in Evaluation of Parapharyngeal Masses: Correlation with Histopathological Findings
Journal of Medical Science And clinical Research, 2018
Introduction: Parapharyngeal space is one of potential fascial planes of head and neck, that may become involved by various pathological processes. The aim of study was to establish diagnostic value of MRI for detection, characterization and localization of parapharyngeal masses and correlating these with histopathological findings which will be of great help for surgeon to adopt right choice of surgical approach and non operative management by superior diagnostic value of MRI and minimize surgical morbidity, as well as risk of surgical recurrence. Materials and Methods: The study was conducted for this purpose in 30 patients from all age groups, of either sex, having parapharyngeal masses suspected clinically or ultrasonographically. Results: The MRI findings positively correlated with histopathology and has superior diagnostic value for detection, characterization and localization of parapharyngeal masses. Out of total 30 patients, 16.67% had origin primarily from paraphayngeal space and 50% had secondary extension to parapharyngeal space. Rest 33.34% had no extension to parapharngeal space. Male have more incidence as 20 male and 10 female. Male have maximum incidence in 5 th decade of life while female have almost equal incidence in 3 rd , 4 th and 5 th decade. Most common presenting complain was neck swelling and parotid gland (70%) was most common involved. Conclusions: MRI almost correctly differentiated all benign and malignant lesions and almost correctly characterized all lesions and excellent regarding tissue content and was in agreement with the histopathological diagnosis.
Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2019
Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pleura and barely reported in parapharyngeal space. SFT is often misdiagnosed due to its microscopic resemblance to several other spindle cell tumors; however, there are specific diagnostic features on MRI and immunohistochemical.We herein report a case of a 65-year-old male patient with SFT arisen in the parapharyngeal space completely resected through a transoral approach. Also, a comprehensive review of previously published cases and case series of parapharyngeal space SFTs and hemangiopericytoma (HPC) reported globally in English up to August 2018 using the PubMed/Medline databases was presented. In addition to the current case, there are thirteen SFTs and thirteen HPCs reported cases. All cases were presented and analyzed. Males are predominantly affected. Actually, 23% of HPCs reported cases presented with the histological indicator of aggressive behavior while none of SFTs reported ...
Solitary fibrous tumor of the larynx: a case report and review of the literature
Archives of pathology & laboratory medicine, 2006
Solitary fibrous tumors are relatively rare mesenchymal neoplasms that were originally described as pleural- or peritoneal-based lesions. Although they were considered a form of mesothelioma, subsequent investigation failed to reveal mesothelial differentiation. Characterization of their histologic and immunohistochemical features, as well as identification in a multitude of nonmesothelial-based locations has further served to distinguish these lesions from the more diffuse and aggressive mesothelioma. Reports of solitary fibrous tumor in the larynx are extremely rare. We report a case of solitary fibrous tumor of the larynx in a 38-year-old man.
Clinical Imaging, 2013
Although neurofibroma is a common soft tissue tumor of the head and neck, neurofibroma of the oropharynx is extremely rare. Here, we report a case of neurofibroma of the palatine tonsil. Magnetic resonance imaging was useful in demonstrating the location of the tumor as well as its well-defined appearance. The present case showed a target sign; the tumor exhibited peripheral hyperintensity and central hypointensity on T2-weighted images, reflecting its characteristic zonal anatomy.