Tissue culture of cat retinal pigment epithelium (original) (raw)

This research presents a method for culturing retinal pigment epithelium (RPE) cells from normal rat eyes, examining their morphological characteristics and lysosomal enzyme activities. The study demonstrated that RPE cells maintained normal features in vitro and showed significantly higher activities of arylsulfatase A and B compared to cat peripheral leukocytes and skin fibroblasts. The cultured RPE cells provide a model for investigating retinal diseases, particularly those impacting RPE function.