TOPPITS: Trial Of Proton Pump Inhibitors in Throat Symptoms. Study protocol for a randomised controlled trial (original) (raw)

A randomised, placebo controlled trial of extra-oesophageal reflux treatment in the management of upper respiratory symptoms. [TOPPITS: Trial of Proton Pump Inhibitors in Throat Symptoms]

Jan Lecouturier

http://isrctn.org/>, 2014

View PDFchevron_right

Continuous Versus On-Demand Proton Pump Inhibitor Treatment for Laryngopharyngeal Reflux: A Randomized Clinical Trial

Adang Bachtiar

International Journal of Applied Pharmaceutics

View PDFchevron_right

Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT

Jan Lecouturier

Health Technology Assessment, 2021

View PDFchevron_right

CONTINUOUS VERSUS ON-DEMAND PROTON PUMP INHIBITOR TREATMENT FOR LARYNGOPHARYNGEAL REFLUX: A RANDOMIZED CLINICAL TRIAL Original Article

International Journal of Applied Pharmaceutics (IJAP)

International Journal of Applied Pharmaceutics, 2019

View PDFchevron_right

Predictors of response to short-term proton pump inhibitor treatment in laryngopharyngeal reflux patients

Nora Šiupšinskienė

The Journal of Laryngology & Otology, 2008

View PDFchevron_right

Proton pump inhibitors effect on the quality of life of patients with laryngopharyngeal reflux

Susyana Tamin

Oto Rhino Laryngologica Indonesiana, 2022

View PDFchevron_right

Systematic review and meta-analysis: proton pump inhibitors slightly decrease the severity of chronic cough

Mahmoud Obeidat

Scientific reports, 2024

View PDFchevron_right

Are persistent throat symptoms atypical features of gastric reflux and should they be treated with proton pump inhibitors?

Janet Wilson

BMJ (Clinical research ed.), 2014

View PDFchevron_right

A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease

Jennifer Forero

Canadian Journal of Gastroenterology and Hepatology, 2019

View PDFchevron_right

A clinical study of symptomatic profile and response in objective and subjective parameters to proton pump inhibitor in laryngopharyngeal reflux

angshuman dutta

International Journal of Otorhinolaryngology and Head and Neck Surgery

View PDFchevron_right

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: a single-arm (pre and post) quasi-experimental study

Mahmoud Ragaee

The Egyptian Journal of Otolaryngology

View PDFchevron_right

Oropharyngeal pH Testing Does Not Predict Response to Proton Pump Inhibitor Therapy in Patients with Laryngeal Symptoms

Michiel Bove

The American journal of gastroenterology, 2016

View PDFchevron_right

Meta‐analysis: comparing the efficacy of proton pump inhibitors in short‐term use

B. Van Hout

Alimentary Pharmacology & Therapeutics, 2003

View PDFchevron_right

Recent effectiveness of proton pump inhibitors for severe reflux esophagitis: the first multicenter prospective study in Japan

Koji Nakada

Journal of clinical biochemistry and nutrition, 2015

View PDFchevron_right

Effect of Proton Pump Inhibitors in the Treatment of Laryngopharyngeal Reflux

IOSR Journals

View PDFchevron_right

Management of Reflux Symptoms with Over-the-Counter Proton Pump Inhibitors: Issues and Proposed Guidelines

Peter Layer

Digestion, 2009

View PDFchevron_right

Proton Pump Inhibitors Versus Solitary Lifestyle Modification in Management of Laryngopharyngeal Reflux and Evaluating Who is at Risk: Scenario in a Developing Country

Anoop Saraya

Clinical Medicine Insights: Ear, Nose and Throat, 2014

View PDFchevron_right

Validation of a short questionnaire in English and French for use in patients with persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy: The PASS (Proton pump inhibitor Acid Suppression Symptom) test

SERGIO ESCOBEDO

View PDFchevron_right

Proton Pump Inhibitor Therapy for Suspected GERD-Related Chronic Laryngitis: A Meta-Analysis of Randomized Controlled Trials

Thomas Havas

The American Journal of Gastroenterology, 2006

View PDFchevron_right

On-Demand Therapy with Proton Pump Inhibitors for Maintenance Treatment of Nonerosive Reflux Disease or Mild Erosive Esophagitis: A Systematic Review and Meta-Analysis

Colin Howden

Gastroenterology research and practice, 2018

View PDFchevron_right

Pharyngeal pH measurements in patients with laryngeal symptoms prior to and during proton pump inhibitor therapy

Charles Pope

Gastroenterology, 2000

View PDFchevron_right

Pharyngeal pH measurements in patients with respiratory symptoms before and during proton pump inhibitor therapy

Pablo Omelanczuk

American Journal of Surgery - AMER J SURG, 2001

View PDFchevron_right

Unexpected consequences of proton pump inhibitor use

Kenneth Altman

Otolaryngology - Head and Neck Surgery, 2009

View PDFchevron_right

Poor effectiveness of proton pump inhibitors in non-erosive reflux disease: the truth in the end!

Carmelo Scarpignato

Neurogastroenterology & Motility, 2012

View PDFchevron_right

Systematic review of proton pump inhibitors for the acute treatment of reflux oesophagitis

Steve Edwards

Alimentary Pharmacology and Therapeutics, 2001

View PDFchevron_right

Rabeprazole Is Effective in Treating Laryngopharyngeal Reflux in a Randomized Placebo-Controlled Trial

Manwa Ng

Clinical Gastroenterology and Hepatology, 2010

View PDFchevron_right

Systematic review: proton pump inhibitors (PPIs) for the healing of reflux oesophagitis – a comparison of esomeprazole with other PPIs

Steve Edwards

Alimentary Pharmacology and Therapeutics, 2006

View PDFchevron_right

Proton pump inhibitors in gastroesophageal reflux disease: a custom-tailored therapeutic regimen

Antonio Gamiz, Adolfo Saez, Juan Lopez-alvarenga

Revista Española de Enfermedades Digestivas, 2012

View PDFchevron_right

Effects of a proton pump inhibitor on laryngeal irritation in patients with laryngopharyngeal reflux

Mehmet Kulekci

Ent updates, 2015

View PDFchevron_right

Key Considerations From a Health Authority Perspective When Proton Pump Inhibitors Are Used to Treat Gastroesophageal Reflux Disease (GERD) and Their Implications

Phumzile Skosana

Cureus

View PDFchevron_right

The Role of Proton Pump Inhibitors in Gastro-oesophageal Reflux Disease

Ronnie Fass

Drugs, 2004

View PDFchevron_right

Effectiveness of proton pump inhibitors in nonerosive reflux disease

Ronnie Fass

Clinical Gastroenterology and Hepatology, 2004

View PDFchevron_right

Is Proton Pump Inhibitor Therapy for Reflux Esophagitis Sufficient?: A Large Real-world Survey of Japanese Patients

Koji Nakada

Internal Medicine, 2013

View PDFchevron_right

Clinical features and therapeutic responses to proton pump inhibitor in patients with severe reflux esophagitis: A multicenter prospective observational study

Koji Nakada

JGH Open, 2020

View PDFchevron_right

Comparison of the Degree of Duodenogastroesophageal Reflux and Acid Reflux Between Patients Who Failed to Respond and Those Who Were Successfully Treated With a Proton Pump Inhibitor Once Daily

Ronnie Fass

The American Journal of Gastroenterology, 2009

View PDFchevron_right